ENSG00000178773

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000268720 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding protein_coding 17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 0.8590843 2.5772530 0.0000000 0.2615218 0.0000000 -8.0152773 0.01885833 0.056575 0.000000 -0.056575 0.66997627 0.02188994 FALSE TRUE
ENST00000319518 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding protein_coding 17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 1.0659709 0.7497068 1.4370768 0.7497068 0.2184237 0.9296268 0.27685833 0.017700 0.400300 0.382600 0.02188994 0.02188994 FALSE TRUE
ENST00000564421 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding protein_coding_CDS_not_defined 17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 2.2930515 6.2228750 0.0000000 0.7285020 0.0000000 -9.2837540 0.09340833 0.136400 0.000000 -0.136400 0.18925066 0.02188994 FALSE TRUE
MSTRG.11742.11 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding   17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 1.9722948 5.6743882 0.1803140 0.5153627 0.1138352 -4.9005512 0.06135000 0.124625 0.045800 -0.078825 0.99284725 0.02188994 FALSE TRUE
MSTRG.11742.12 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding   17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 3.0408767 7.8067501 0.9319698 0.4871854 0.1199834 -3.0528162 0.18030833 0.171875 0.257450 0.085575 0.99284725 0.02188994 TRUE TRUE
MSTRG.11742.3 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding   17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 1.2096688 3.3446586 0.2351224 0.2318295 0.0454856 -3.7745915 0.05069167 0.073825 0.067475 -0.006350 0.99323661 0.02188994 FALSE TRUE
MSTRG.11742.7 ENSG00000178773 No_inf pgwt_inf CPNE7 protein_coding   17.58256 45.55169 3.608875 1.140653 0.3227231 -3.654208 2.4624759 6.8050366 0.3536236 0.4274166 0.2155444 -4.2282038 0.09879167 0.150025 0.103825 -0.046200 0.99284725 0.02188994 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000178773 E001 1.0170095 0.2147266615 0.200262799 0.51861803 16 89575207 89575281 75 + 0.416 0.161 -1.846
ENSG00000178773 E002 7.0227042 0.0019809900 0.789746011 0.92724503 16 89575282 89575748 467 + 0.625 0.675 0.212
ENSG00000178773 E003 0.7878527 0.0134158823 1.000000000 1.00000000 16 89575749 89575757 9 + 0.000 0.161 11.073
ENSG00000178773 E004 0.7878527 0.0134158823 1.000000000 1.00000000 16 89575758 89575767 10 + 0.000 0.161 11.073
ENSG00000178773 E005 0.9190819 0.0128338244 1.000000000 1.00000000 16 89575768 89575781 14 + 0.000 0.182 11.259
ENSG00000178773 E006 7.6423268 0.0113705231 0.628314889 0.85108755 16 89575782 89576071 290 + 0.765 0.695 -0.288
ENSG00000178773 E007 1.8184916 0.0891875430 1.000000000 1.00000000 16 89577513 89577538 26 + 0.256 0.294 0.269
ENSG00000178773 E008 13.3957939 0.0010276275 0.038985558 0.21553711 16 89577539 89577721 183 + 1.116 0.883 -0.863
ENSG00000178773 E009 1.8208777 0.0078021829 1.000000000 1.00000000 16 89578857 89578996 140 + 0.256 0.294 0.269
ENSG00000178773 E010 10.4321428 0.0013590207 0.236169539 0.56137985 16 89582410 89583282 873 + 0.625 0.824 0.817
ENSG00000178773 E011 1.3153710 0.1797682208 0.707247980 0.89082513 16 89583354 89583443 90 + 0.000 0.242 11.521
ENSG00000178773 E012 3.6426016 0.0051017990 0.806871847 0.93396747 16 89583444 89583528 85 + 0.416 0.468 0.269
ENSG00000178773 E013 9.9389704 0.0017011902 0.170371410 0.47808102 16 89583697 89583771 75 + 0.956 0.778 -0.687
ENSG00000178773 E014 10.6438654 0.0014353506 0.960569897 0.99059412 16 89584028 89584102 75 + 0.821 0.819 -0.010
ENSG00000178773 E015 10.0660537 0.0015127908 0.182819762 0.49569283 16 89584774 89584820 47 + 0.956 0.783 -0.666
ENSG00000178773 E016 8.7743731 0.0017035530 0.177108509 0.48841901 16 89584821 89584857 37 + 0.916 0.732 -0.719
ENSG00000178773 E017 11.6055926 0.0085997266 0.122627674 0.40549475 16 89585464 89585553 90 + 1.027 0.833 -0.731
ENSG00000178773 E018 13.4487154 0.0011020410 0.264027001 0.59207271 16 89585687 89585785 99 + 1.027 0.895 -0.493
ENSG00000178773 E019 13.3724815 0.0010713356 0.897519089 0.96930497 16 89586670 89586756 87 + 0.916 0.903 -0.047
ENSG00000178773 E020 8.5794797 0.0016902010 0.807141502 0.93415701 16 89587043 89587102 60 + 0.701 0.744 0.177
ENSG00000178773 E021 3.7562827 0.0041475299 0.713384028 0.89368728 16 89587333 89587458 126 + 0.533 0.468 -0.316
ENSG00000178773 E022 4.5614930 0.0032043596 0.546074826 0.80877516 16 89587459 89587555 97 + 0.416 0.539 0.613
ENSG00000178773 E023 3.7754085 0.0047060978 0.765439535 0.91682699 16 89587556 89587582 27 + 0.416 0.479 0.324
ENSG00000178773 E024 6.2174252 0.0022751030 0.622640126 0.84878727 16 89587583 89587762 180 + 0.701 0.624 -0.327
ENSG00000178773 E025 5.8947337 0.0055255390 0.082497751 0.32839499 16 89587763 89587927 165 + 0.256 0.631 2.028
ENSG00000178773 E026 1.4436052 0.1626255386 0.593362487 0.83421195 16 89587928 89587965 38 + 0.000 0.260 11.648
ENSG00000178773 E027 5.9857356 0.0036567949 0.634958238 0.85454575 16 89587966 89588220 255 + 0.533 0.624 0.410
ENSG00000178773 E028 2.8544919 0.0050920916 0.906488962 0.97241288 16 89588221 89588379 159 + 0.416 0.396 -0.109
ENSG00000178773 E029 15.6465598 0.0040823173 0.149888961 0.44791829 16 89588380 89588674 295 + 0.765 0.978 0.816
ENSG00000178773 E030 17.6041004 0.0271213431 0.464130182 0.75701678 16 89588675 89588803 129 + 1.088 1.004 -0.308
ENSG00000178773 E031 7.2634441 0.0026758190 0.884421925 0.96380631 16 89588804 89588808 5 + 0.701 0.681 -0.081
ENSG00000178773 E032 12.8777648 0.0011444517 0.624062892 0.84943983 16 89589897 89589951 55 + 0.821 0.895 0.285
ENSG00000178773 E033 13.1442063 0.0012426607 0.583185920 0.82853417 16 89591007 89591058 52 + 0.821 0.903 0.316
ENSG00000178773 E034 13.4996142 0.0009950351 0.922354765 0.97797998 16 89591127 89591260 134 + 0.916 0.907 -0.031
ENSG00000178773 E035 0.2623781 0.0162395811 0.814130732   16 89592244 89592291 48 + 0.000 0.060 9.674
ENSG00000178773 E036 2.5917317 0.0675071227 0.786362756 0.92592560 16 89593820 89594099 280 + 0.416 0.370 -0.261
ENSG00000178773 E037 0.3940400 0.0160404433 1.000000000   16 89594100 89594158 59 + 0.000 0.088 10.202
ENSG00000178773 E038 29.6137984 0.0004895514 0.974123101 0.99548812 16 89595367 89595575 209 + 1.212 1.220 0.028
ENSG00000178773 E039 10.7000376 0.0023607669 0.212856077 0.53487067 16 89595576 89595603 28 + 0.625 0.833 0.854
ENSG00000178773 E040 6.5922228 0.0020861845 0.407291511 0.71660487 16 89595604 89595769 166 + 0.765 0.639 -0.525
ENSG00000178773 E041 4.1152335 0.0120655735 0.188830653 0.50312831 16 89595770 89595830 61 + 0.701 0.479 -0.998
ENSG00000178773 E042 7.5495063 0.0112204036 0.678351209 0.87607231 16 89595831 89595924 94 + 0.625 0.701 0.324
ENSG00000178773 E043 13.0402547 0.0013203744 0.124266780 0.40837107 16 89595925 89596351 427 + 1.059 0.878 -0.672
ENSG00000178773 E044 79.1223939 0.0013219715 0.004745217 0.05615564 16 89596484 89597246 763 + 1.452 1.641 0.644

Help

Please Click HERE to learn more details about the results from DEXseq.