ENSG00000178917

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000436261 ENSG00000178917 No_inf pgwt_inf ZNF852 protein_coding protein_coding 12.00788 33.27309 1.386609 11.00271 0.2755298 -4.574789 0.8976532 1.2834007 0.85179894 0.2166518 0.13735239 -0.5857461 0.39344167 0.053175 0.697275 0.644100 7.036306e-02 8.293072e-06 FALSE TRUE
ENST00000489411 ENSG00000178917 No_inf pgwt_inf ZNF852 protein_coding protein_coding_CDS_not_defined 12.00788 33.27309 1.386609 11.00271 0.2755298 -4.574789 0.1307089 0.3170449 0.07508193 0.3170449 0.07508193 -1.9425639 0.02478333 0.009225 0.065125 0.055900 9.803593e-01 8.293072e-06 FALSE TRUE
ENST00000650400 ENSG00000178917 No_inf pgwt_inf ZNF852 protein_coding protein_coding 12.00788 33.27309 1.386609 11.00271 0.2755298 -4.574789 0.6510246 0.7566900 0.44394562 0.2993919 0.37509857 -0.7561239 0.25976667 0.025125 0.225150 0.200025 9.770093e-01 8.293072e-06 FALSE TRUE
MSTRG.20047.5 ENSG00000178917 No_inf pgwt_inf ZNF852 protein_coding   12.00788 33.27309 1.386609 11.00271 0.2755298 -4.574789 10.2947827 30.8843480 0.00000000 10.9188003 0.00000000 -11.5931272 0.30374167 0.911225 0.000000 -0.911225 8.293072e-06 8.293072e-06   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000178917 E001 2.3045525 0.009035239 0.125838298 0.41126615 3 44494847 44495101 255 - 0.628 0.419 -1.001
ENSG00000178917 E002 4.5668599 0.004666807 0.505186921 0.78380445 3 44498970 44499522 553 - 0.780 0.704 -0.307
ENSG00000178917 E003 1.4206607 0.012000145 0.014800828 0.11948248 3 44499523 44499575 53 - 0.563 0.207 -2.126
ENSG00000178917 E004 2.3568131 0.006778104 0.919775082 0.97673895 3 44499576 44499893 318 - 0.527 0.510 -0.082
ENSG00000178917 E005 5.7335984 0.004047508 0.002342578 0.03406138 3 44499894 44500634 741 - 0.597 0.909 1.266
ENSG00000178917 E006 0.2450991 0.016993199 0.775412065   3 44500635 44500637 3 - 0.112 0.080 -0.541
ENSG00000178917 E007 0.2450383 0.017501032 0.775972061   3 44500638 44502541 1904 - 0.112 0.080 -0.541
ENSG00000178917 E008 1.3579629 0.010010882 0.761752517 0.91540002 3 44502542 44502668 127 - 0.394 0.346 -0.278
ENSG00000178917 E009 0.0000000       3 44502669 44502964 296 -      
ENSG00000178917 E010 0.1145948 0.011790677 0.371430921   3 44502965 44503056 92 - 0.112 0.000 -9.704
ENSG00000178917 E011 0.0000000       3 44503057 44503110 54 -      
ENSG00000178917 E012 1.5070298 0.015938471 0.575687295 0.82478978 3 44506794 44506926 133 - 0.339 0.419 0.459
ENSG00000178917 E013 1.0156119 0.012670927 0.336940438 0.65973813 3 44510553 44510636 84 - 0.202 0.346 1.044

Help

Please Click HERE to learn more details about the results from DEXseq.