ENSG00000180182

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000416199 ENSG00000180182 No_inf pgwt_inf MED14 protein_coding protein_coding 20.85505 13.64876 25.79464 0.5997096 0.4545697 0.9178039 1.635104 1.053111 2.191207 1.0531112 1.2714845 1.0500020 0.07429167 0.069125 0.08250 0.013375 0.99284725 0.01247716 FALSE TRUE
ENST00000433003 ENSG00000180182 No_inf pgwt_inf MED14 protein_coding protein_coding 20.85505 13.64876 25.79464 0.5997096 0.4545697 0.9178039 3.780332 2.604109 4.856293 0.8859994 0.4674759 0.8965037 0.18510833 0.198000 0.18885 -0.009150 1.00000000 0.01247716 FALSE TRUE
ENST00000495865 ENSG00000180182 No_inf pgwt_inf MED14 protein_coding protein_coding_CDS_not_defined 20.85505 13.64876 25.79464 0.5997096 0.4545697 0.9178039 1.399329 0.000000 2.920171 0.0000000 0.4423119 8.1948410 0.05520833 0.000000 0.11410 0.114100 0.01247716 0.01247716 FALSE TRUE
MSTRG.29882.3 ENSG00000180182 No_inf pgwt_inf MED14 protein_coding   20.85505 13.64876 25.79464 0.5997096 0.4545697 0.9178039 1.586122 1.528953 2.573460 0.6056355 1.0539926 0.7473556 0.08052500 0.112100 0.10035 -0.011750 1.00000000 0.01247716 FALSE TRUE
MSTRG.29882.4 ENSG00000180182 No_inf pgwt_inf MED14 protein_coding   20.85505 13.64876 25.79464 0.5997096 0.4545697 0.9178039 10.450679 6.749147 11.932848 0.8091662 1.3163782 0.8212340 0.50366667 0.494425 0.46290 -0.031525 1.00000000 0.01247716 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000180182 E001 0.1316618 0.0123099172 3.096062e-01   X 40648305 40649542 1238 - 0.000 0.120 9.650
ENSG00000180182 E002 0.2277562 0.0154448143 4.824523e-01   X 40649543 40649557 15 - 0.139 0.000 -12.965
ENSG00000180182 E003 3.0404879 0.1322777455 5.788844e-01 8.258804e-01 X 40649558 40649663 106 - 0.561 0.652 0.402
ENSG00000180182 E004 2.4361656 0.1804833495 5.972656e-01 8.362506e-01 X 40649664 40649672 9 - 0.488 0.586 0.460
ENSG00000180182 E005 143.9208955 0.0001282283 7.628266e-08 5.509580e-06 X 40649673 40651879 2207 - 2.102 2.219 0.394
ENSG00000180182 E006 4.5326933 0.0056624333 1.629912e-01 4.672761e-01 X 40653872 40654363 492 - 0.662 0.827 0.672
ENSG00000180182 E007 30.0355627 0.0004735922 2.426883e-01 5.689434e-01 X 40654364 40654556 193 - 1.459 1.519 0.208
ENSG00000180182 E008 18.1669069 0.0021237283 7.284661e-01 9.009234e-01 X 40654935 40655060 126 - 1.286 1.259 -0.096
ENSG00000180182 E009 19.1452884 0.0021532908 1.721888e-01 4.810703e-01 X 40659227 40659334 108 - 1.334 1.235 -0.346
ENSG00000180182 E010 28.6218527 0.0031182701 6.572471e-01 8.661994e-01 X 40659428 40659607 180 - 1.476 1.447 -0.099
ENSG00000180182 E011 0.0000000       X 40659608 40659819 212 -      
ENSG00000180182 E012 34.3732915 0.0020245651 3.128709e-01 6.387365e-01 X 40662925 40663160 236 - 1.520 1.570 0.173
ENSG00000180182 E013 26.0806444 0.0005490092 1.152056e-01 3.923436e-01 X 40664307 40664489 183 - 1.462 1.366 -0.331
ENSG00000180182 E014 16.6535266 0.0008716854 3.157572e-01 6.417121e-01 X 40666720 40666851 132 - 1.269 1.193 -0.266
ENSG00000180182 E015 17.2556709 0.0008686397 2.378719e-02 1.603657e-01 X 40671861 40671972 112 - 1.315 1.147 -0.593
ENSG00000180182 E016 15.4396840 0.0008999895 1.334667e-02 1.119661e-01 X 40675221 40675361 141 - 1.277 1.083 -0.691
ENSG00000180182 E017 26.9815425 0.0134773198 9.792635e-02 3.606634e-01 X 40679864 40680133 270 - 1.486 1.360 -0.437
ENSG00000180182 E018 17.0068736 0.0009728625 1.676728e-01 4.742888e-01 X 40680758 40680910 153 - 1.207 1.302 0.334
ENSG00000180182 E019 0.0000000       X 40681848 40681851 4 -      
ENSG00000180182 E020 12.1657077 0.0011958031 1.633829e-01 4.677675e-01 X 40681852 40681943 92 - 1.063 1.175 0.402
ENSG00000180182 E021 15.7259532 0.0008993063 5.062130e-01 7.844609e-01 X 40682603 40682749 147 - 1.197 1.243 0.165
ENSG00000180182 E022 13.0601410 0.0015617266 5.758981e-01 8.248124e-01 X 40682836 40682996 161 - 1.123 1.166 0.153
ENSG00000180182 E023 7.1721340 0.0019152796 3.756120e-01 6.933384e-01 X 40688454 40688530 77 - 0.942 0.847 -0.360
ENSG00000180182 E024 10.6046668 0.0124046050 1.575854e-01 4.596501e-01 X 40692183 40692317 135 - 1.110 0.966 -0.527
ENSG00000180182 E025 10.9777287 0.0347051387 3.161978e-01 6.419489e-01 X 40692708 40692902 195 - 1.117 0.995 -0.443
ENSG00000180182 E026 8.5694024 0.0016961973 8.806534e-01 9.622783e-01 X 40697024 40697183 160 - 0.969 0.981 0.045
ENSG00000180182 E027 7.4896445 0.0261325273 8.178304e-01 9.375104e-01 X 40701165 40701243 79 - 0.913 0.935 0.086
ENSG00000180182 E028 8.5181167 0.0280752219 6.708115e-01 8.727258e-01 X 40703444 40703569 126 - 0.995 0.935 -0.220
ENSG00000180182 E029 8.2380242 0.0362286937 3.462257e-01 6.672865e-01 X 40709348 40709459 112 - 1.003 0.885 -0.443
ENSG00000180182 E030 10.1217721 0.0014144752 9.617866e-01 9.908714e-01 X 40709979 40710129 151 - 1.042 1.035 -0.024
ENSG00000180182 E031 8.4697554 0.0018744460 6.279009e-01 8.509330e-01 X 40711169 40711301 133 - 0.951 0.995 0.165
ENSG00000180182 E032 8.2887447 0.0179302051 2.060598e-01 5.259656e-01 X 40712186 40712293 108 - 0.902 1.035 0.494
ENSG00000180182 E033 8.2177918 0.0018628183 1.553228e-01 4.562816e-01 X 40712914 40713042 129 - 1.011 0.866 -0.543
ENSG00000180182 E034 5.3249766 0.0025365434 7.074411e-02 3.018246e-01 X 40713778 40713831 54 - 0.870 0.652 -0.879
ENSG00000180182 E035 6.3062856 0.0021991383 1.763276e-01 4.874768e-01 X 40713832 40713877 46 - 0.913 0.761 -0.592
ENSG00000180182 E036 6.8590963 0.0022405671 3.545313e-02 2.034941e-01 X 40713878 40713907 30 - 0.969 0.736 -0.903
ENSG00000180182 E037 12.3682665 0.0011243745 4.611934e-02 2.362531e-01 X 40714537 40714710 174 - 1.181 1.009 -0.621
ENSG00000180182 E038 1.7522327 0.0085215876 4.282187e-02 2.272919e-01 X 40714711 40715051 341 - 0.289 0.586 1.597
ENSG00000180182 E039 0.0000000       X 40726455 40726527 73 -      
ENSG00000180182 E040 0.1139502 0.0112216009 1.000000e+00   X 40726528 40726745 218 - 0.075 0.000 -12.039
ENSG00000180182 E041 6.6511991 0.0022694443 1.028829e-01 3.695104e-01 X 40726746 40726851 106 - 0.942 0.761 -0.701
ENSG00000180182 E042 2.8761940 0.0048536409 6.987400e-01 8.859944e-01 X 40729319 40729345 27 - 0.604 0.549 -0.251
ENSG00000180182 E043 0.1139502 0.0112216009 1.000000e+00   X 40729346 40729540 195 - 0.075 0.000 -12.039
ENSG00000180182 E044 0.0000000       X 40734823 40734879 57 -      
ENSG00000180182 E045 2.6135808 0.0054038178 3.311072e-01 6.548657e-01 X 40735198 40735542 345 - 0.604 0.463 -0.666
ENSG00000180182 E046 0.2456901 0.0164598093 6.823533e-01   X 40735722 40735857 136 - 0.075 0.120 0.749
ENSG00000180182 E047 0.3598652 0.2024369169 1.000000e+00   X 40735858 40735918 61 - 0.139 0.120 -0.250

Help

Please Click HERE to learn more details about the results from DEXseq.