ENSG00000180773

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326402 ENSG00000180773 No_inf pgwt_inf SLC36A4 protein_coding protein_coding 16.65665 6.890197 20.72283 1.036524 1.205683 1.587208 4.034308 0.1435126 6.839595 0.1435126 0.3303303 5.479590 0.1993667 0.024225 0.332275 0.308050 9.155653e-02 2.388853e-05 FALSE TRUE
ENST00000524875 ENSG00000180773 No_inf pgwt_inf SLC36A4 protein_coding nonsense_mediated_decay 16.65665 6.890197 20.72283 1.036524 1.205683 1.587208 1.197088 0.2376601 2.117125 0.2376601 1.2924649 3.102472 0.0578250 0.025075 0.101725 0.076650 9.928472e-01 2.388853e-05 TRUE TRUE
ENST00000529184 ENSG00000180773 No_inf pgwt_inf SLC36A4 protein_coding protein_coding 16.65665 6.890197 20.72283 1.036524 1.205683 1.587208 4.747132 1.0788345 5.410828 0.6508185 1.5078823 2.315729 0.2644917 0.159125 0.269300 0.110175 9.928472e-01 2.388853e-05 FALSE TRUE
ENST00000534116 ENSG00000180773 No_inf pgwt_inf SLC36A4 protein_coding protein_coding 16.65665 6.890197 20.72283 1.036524 1.205683 1.587208 4.159539 0.9068596 5.942552 0.9068596 2.0502356 2.698736 0.2015083 0.095650 0.277075 0.181425 9.424277e-01 2.388853e-05 FALSE TRUE
MSTRG.5367.3 ENSG00000180773 No_inf pgwt_inf SLC36A4 protein_coding   16.65665 6.890197 20.72283 1.036524 1.205683 1.587208 1.944438 4.2655872 0.000000 0.2075709 0.0000000 -8.739979 0.2428083 0.661425 0.000000 -0.661425 2.388853e-05 2.388853e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000180773 E001 0.2281253 0.0153452880 5.711539e-01   11 93144174 93144240 67 - 0.131 0.000 -10.079
ENSG00000180773 E002 0.5702815 0.0190687930 1.053622e-01   11 93144241 93144328 88 - 0.274 0.000 -13.397
ENSG00000180773 E003 103.1832830 0.0001813107 2.442245e-10 2.735211e-08 11 93144329 93148147 3819 - 1.941 2.091 0.503
ENSG00000180773 E004 10.1799128 0.0019728178 8.374088e-01 9.458679e-01 11 93148148 93148314 167 - 1.043 1.022 -0.078
ENSG00000180773 E005 39.1564701 0.0004840788 1.525552e-01 4.520285e-01 11 93148315 93148844 530 - 1.615 1.544 -0.241
ENSG00000180773 E006 0.3946917 0.0249435030 2.634459e-02   11 93153964 93154107 144 - 0.000 0.305 12.979
ENSG00000180773 E007 5.8225740 0.0025832125 2.694969e-01 5.975303e-01 11 93154108 93154120 13 - 0.773 0.892 0.463
ENSG00000180773 E008 7.7792831 0.0220860694 8.383109e-01 9.461466e-01 11 93154121 93154156 36 - 0.942 0.911 -0.119
ENSG00000180773 E009 13.1733262 0.0090846644 8.217859e-01 9.393912e-01 11 93154157 93154277 121 - 1.147 1.122 -0.091
ENSG00000180773 E010 0.6388510 0.0149079013 3.696400e-02   11 93154278 93155488 1211 - 0.071 0.373 2.948
ENSG00000180773 E011 14.5451575 0.0016600773 2.903530e-01 6.183566e-01 11 93162706 93162875 170 - 1.208 1.122 -0.308
ENSG00000180773 E012 12.8428646 0.0010937243 1.618161e-01 4.653243e-01 11 93165918 93166016 99 - 1.169 1.049 -0.430
ENSG00000180773 E013 0.1311489 0.0122329192 2.639678e-01   11 93166017 93167530 1514 - 0.000 0.127 11.555
ENSG00000180773 E014 24.5758256 0.0006798377 2.186911e-01 5.418134e-01 11 93167944 93168171 228 - 1.421 1.344 -0.268
ENSG00000180773 E015 0.4908428 0.0316018492 5.181021e-01   11 93170154 93170221 68 - 0.131 0.225 0.948
ENSG00000180773 E016 9.7657113 0.0050901874 3.724413e-01 6.904151e-01 11 93180797 93180881 85 - 1.050 0.962 -0.325
ENSG00000180773 E017 6.1364003 0.0166805303 1.158820e-01 3.934830e-01 11 93181691 93181786 96 - 0.906 0.706 -0.789
ENSG00000180773 E018 2.6581322 0.0067267091 4.685458e-03 5.570518e-02 11 93182806 93182834 29 - 0.672 0.225 -2.444
ENSG00000180773 E019 5.6645609 0.0054072738 9.908923e-02 3.630012e-01 11 93182835 93182894 60 - 0.876 0.676 -0.802
ENSG00000180773 E020 8.0876416 0.0057448286 2.979557e-01 6.256350e-01 11 93184430 93184520 91 - 0.984 0.873 -0.419
ENSG00000180773 E021 0.4742351 0.0159357766 7.365317e-01   11 93185220 93185690 471 - 0.184 0.127 -0.637
ENSG00000180773 E022 8.4799183 0.0692365456 8.746997e-02 3.390850e-01 11 93185691 93185814 124 - 1.043 0.785 -0.979
ENSG00000180773 E023 0.1316618 0.0123119115 2.638546e-01   11 93197192 93197455 264 - 0.000 0.127 11.555
ENSG00000180773 E024 8.0010064 0.0051957968 1.673626e-02 1.293108e-01 11 93197778 93197991 214 - 1.022 0.760 -0.999

Help

Please Click HERE to learn more details about the results from DEXseq.