ENSG00000184060

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000330889 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding protein_coding 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 5.9286563 3.768570 6.3025531 1.2690424 0.7027881 0.7403833 0.32442500 0.186500 0.439875 0.253375 9.770093e-01 1.030764e-06 FALSE TRUE
ENST00000470962 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding retained_intron 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 3.0896984 0.000000 1.9341424 0.0000000 1.1192015 7.6029901 0.14450000 0.000000 0.119600 0.119600 9.378947e-01 1.030764e-06   FALSE
ENST00000480980 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding retained_intron 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 1.5453497 2.527417 1.5876331 0.4179737 0.6034980 -0.6674246 0.09237500 0.126950 0.125250 -0.001700 1.000000e+00 1.030764e-06   FALSE
ENST00000583688 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding protein_coding_CDS_not_defined 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 1.1068870 1.157893 0.8481299 0.4960803 0.1706559 -0.4446401 0.05765833 0.052475 0.059075 0.006600 1.000000e+00 1.030764e-06   FALSE
ENST00000584828 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding protein_coding 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 0.6199541 0.000000 0.7555661 0.0000000 0.7555661 6.2584551 0.03056667 0.000000 0.053925 0.053925 9.928472e-01 1.030764e-06 FALSE FALSE
ENST00000584989 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding protein_coding 20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 2.5072522 1.070985 2.7274030 1.0709851 2.7274030 1.3404612 0.08765000 0.038450 0.113225 0.074775 1.000000e+00 1.030764e-06 FALSE FALSE
MSTRG.12399.11 ENSG00000184060 No_inf pgwt_inf ADAP2 protein_coding   20.16141 20.40312 15.62157 2.594307 2.856044 -0.3850334 2.9437115 8.831134 0.0000000 0.6588361 0.0000000 -9.7880877 0.14770833 0.443125 0.000000 -0.443125 1.030764e-06 1.030764e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000184060 E001 2.2597613 0.0066458085 3.376092e-01 0.6601953167 17 30906344 30906644 301 + 0.422 0.560 0.681
ENSG00000184060 E002 0.0000000       17 30921680 30921703 24 +      
ENSG00000184060 E003 0.7201226 0.0143987960 2.809011e-01 0.6089977267 17 30921704 30921916 213 + 0.321 0.158 -1.319
ENSG00000184060 E004 0.1145948 0.0112012632 4.313692e-01   17 30921917 30921931 15 + 0.105 0.000 -11.695
ENSG00000184060 E005 0.1145948 0.0112012632 4.313692e-01   17 30921932 30921934 3 + 0.105 0.000 -11.695
ENSG00000184060 E006 0.2457437 0.0161232955 8.644508e-01   17 30921935 30921944 10 + 0.105 0.086 -0.319
ENSG00000184060 E007 0.2457437 0.0161232955 8.644508e-01   17 30921945 30921947 3 + 0.105 0.086 -0.319
ENSG00000184060 E008 0.5880947 0.0150987450 1.094459e-01   17 30921948 30921970 23 + 0.321 0.086 -2.319
ENSG00000184060 E009 4.1661509 0.0033783234 1.329132e-03 0.0223003434 17 30921971 30922108 138 + 0.894 0.504 -1.640
ENSG00000184060 E010 6.1032987 0.0024596891 1.795867e-01 0.4918833106 17 30922940 30923070 131 + 0.923 0.781 -0.550
ENSG00000184060 E011 0.2628107 0.0160789254 3.271371e-01   17 30926809 30926826 18 + 0.000 0.158 11.292
ENSG00000184060 E012 4.1114758 0.0037525949 5.498156e-01 0.8108064267 17 30926827 30926918 92 + 0.658 0.731 0.303
ENSG00000184060 E013 5.2590505 0.0029477341 2.439314e-01 0.5702254921 17 30931889 30931968 80 + 0.708 0.840 0.529
ENSG00000184060 E014 7.4780698 0.0036150149 3.304972e-01 0.6542408207 17 30934185 30934297 113 + 0.977 0.880 -0.366
ENSG00000184060 E015 7.3567714 0.0020606895 5.124136e-03 0.0592894248 17 30944907 30945027 121 + 1.056 0.781 -1.043
ENSG00000184060 E016 3.2069089 0.0381527173 8.996576e-01 0.9701300476 17 30945028 30945041 14 + 0.632 0.609 -0.096
ENSG00000184060 E017 3.3032944 0.0335335103 5.033944e-01 0.7827419478 17 30945042 30945053 12 + 0.684 0.585 -0.426
ENSG00000184060 E018 6.4252377 0.0026136054 4.197748e-02 0.2247402134 17 30949287 30949370 84 + 0.977 0.765 -0.813
ENSG00000184060 E019 6.2294471 0.0025419113 2.291892e-01 0.5544448017 17 30953288 30953350 63 + 0.923 0.797 -0.488
ENSG00000184060 E020 0.2631768 0.0163187137 3.264872e-01   17 30954203 30954239 37 + 0.000 0.158 11.292
ENSG00000184060 E021 0.2454678 0.0163161424 8.645117e-01   17 30954240 30954253 14 + 0.105 0.086 -0.318
ENSG00000184060 E022 0.3763310 0.0170266111 7.282848e-01   17 30954254 30954261 8 + 0.105 0.158 0.681
ENSG00000184060 E023 2.2709135 0.0169212574 4.146715e-02 0.2232807593 17 30954262 30954477 216 + 0.658 0.365 -1.434
ENSG00000184060 E024 3.7832271 0.0049037644 1.057173e-01 0.3754296374 17 30954478 30954480 3 + 0.539 0.748 0.904
ENSG00000184060 E025 6.5633119 0.0033537135 8.677190e-01 0.9580133255 17 30954481 30954555 75 + 0.863 0.880 0.065
ENSG00000184060 E026 2.5352714 0.0057653775 1.134991e-01 0.3895781405 17 30956241 30956391 151 + 0.658 0.440 -1.019
ENSG00000184060 E027 0.0000000       17 30956392 30956469 78 +      
ENSG00000184060 E028 0.4906449 0.0163495752 8.267017e-01   17 30956470 30956728 259 + 0.189 0.158 -0.319
ENSG00000184060 E029 110.3808326 0.0001793875 1.526643e-05 0.0006139651 17 30957835 30959484 1650 + 1.990 2.071 0.272

Help

Please Click HERE to learn more details about the results from DEXseq.