ENSG00000185900

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000674676 ENSG00000185900 No_inf pgwt_inf POMK protein_coding protein_coding 30.84892 24.47205 25.63472 10.40792 8.94273 0.0669371 6.997206 6.847200 6.533411 0.2181701 0.4670137 -0.06757677 0.33848333 0.387425 0.314250 -0.073175 9.928472e-01 2.808975e-05 FALSE TRUE
ENST00000675013 ENSG00000185900 No_inf pgwt_inf POMK protein_coding protein_coding_CDS_not_defined 30.84892 24.47205 25.63472 10.40792 8.94273 0.0669371 11.219878 10.202776 0.000000 10.2027758 0.0000000 -9.99615933 0.13114167 0.183200 0.000000 -0.183200 9.928472e-01 2.808975e-05   FALSE
ENST00000676163 ENSG00000185900 No_inf pgwt_inf POMK protein_coding protein_coding_CDS_not_defined 30.84892 24.47205 25.63472 10.40792 8.94273 0.0669371 2.951878 0.000000 8.855634 0.0000000 8.8556344 9.79208006 0.05628333 0.000000 0.168850 0.168850 9.928472e-01 2.808975e-05   FALSE
ENST00000676193 ENSG00000185900 No_inf pgwt_inf POMK protein_coding protein_coding 30.84892 24.47205 25.63472 10.40792 8.94273 0.0669371 4.307221 0.000000 9.116809 0.0000000 0.1542122 9.83396680 0.18830000 0.000000 0.456975 0.456975 2.808975e-05 2.808975e-05 FALSE TRUE
MSTRG.27615.2 ENSG00000185900 No_inf pgwt_inf POMK protein_coding   30.84892 24.47205 25.63472 10.40792 8.94273 0.0669371 3.770686 6.651301 0.000000 0.1093725 0.0000000 -9.37966022 0.21565000 0.382150 0.000000 -0.382150 6.765275e-05 2.808975e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000185900 E001 0.0000000       8 43093498 43093503 6 +      
ENSG00000185900 E002 0.0000000       8 43093504 43093514 11 +      
ENSG00000185900 E003 0.2277562 1.542499e-02 0.336591670   8 43093515 43093535 21 + 0.157 0.000 -10.837
ENSG00000185900 E004 0.3419313 1.576450e-02 0.158553140   8 43093536 43093563 28 + 0.218 0.000 -12.949
ENSG00000185900 E005 0.3759623 1.676368e-02 0.444544977   8 43094451 43094478 28 + 0.085 0.191 1.345
ENSG00000185900 E006 0.0000000       8 43096042 43096071 30 +      
ENSG00000185900 E007 0.5703321 1.463586e-02 0.039048129   8 43097524 43097529 6 + 0.319 0.000 -13.634
ENSG00000185900 E008 1.7804722 2.201645e-02 0.180558762 0.49314828 8 43097530 43097615 86 + 0.530 0.323 -1.114
ENSG00000185900 E009 0.0000000       8 43098789 43098873 85 +      
ENSG00000185900 E010 0.0000000       8 43100239 43100268 30 +      
ENSG00000185900 E011 0.0000000       8 43102222 43102451 230 +      
ENSG00000185900 E012 1.4381820 1.059862e-02 0.457743391 0.75303640 8 43102505 43102554 50 + 0.437 0.323 -0.655
ENSG00000185900 E013 1.4719938 9.106701e-03 0.678562570 0.87618302 8 43102555 43102600 46 + 0.362 0.424 0.345
ENSG00000185900 E014 6.2947448 1.421387e-02 0.631233640 0.85259825 8 43103528 43103788 261 + 0.888 0.832 -0.217
ENSG00000185900 E015 2.4026991 6.128018e-03 0.418939315 0.72532165 8 43103789 43103830 42 + 0.583 0.467 -0.548
ENSG00000185900 E016 2.4533567 9.147807e-02 0.620905605 0.84779271 8 43103831 43105632 1802 + 0.501 0.575 0.346
ENSG00000185900 E017 0.1308632 1.224885e-02 0.421113493   8 43109564 43109849 286 + 0.000 0.106 10.938
ENSG00000185900 E018 0.1315150 1.229976e-02 0.421101987   8 43117433 43117513 81 + 0.000 0.106 10.938
ENSG00000185900 E019 0.3588442 1.664667e-02 0.744121026   8 43120231 43120498 268 + 0.157 0.106 -0.655
ENSG00000185900 E020 10.3830421 1.372674e-03 0.293961043 0.62215938 8 43122107 43122898 792 + 1.097 1.005 -0.339
ENSG00000185900 E021 6.1328704 2.176082e-02 0.466091975 0.75808205 8 43122899 43123199 301 + 0.808 0.897 0.345
ENSG00000185900 E022 1.5862436 3.462965e-02 0.891025400 0.96656874 8 43123200 43123256 57 + 0.402 0.424 0.123
ENSG00000185900 E023 1.2267475 1.583827e-02 0.709619655 0.89208272 8 43123257 43123265 9 + 0.319 0.377 0.345
ENSG00000185900 E024 2.9455181 4.905937e-03 0.558924069 0.81563558 8 43123266 43123341 76 + 0.557 0.635 0.345
ENSG00000185900 E025 14.9392330 9.506709e-04 0.119201988 0.39936784 8 43123342 43124154 813 + 1.254 1.136 -0.417
ENSG00000185900 E026 285.0401558 8.099768e-05 0.108519242 0.38022919 8 43124155 43130019 5865 + 2.466 2.445 -0.069
ENSG00000185900 E027 167.1844023 1.000571e-04 0.005445099 0.06160668 8 43130020 43131389 1370 + 2.199 2.252 0.176

Help

Please Click HERE to learn more details about the results from DEXseq.