ENSG00000185920

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331920 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding protein_coding 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 0.5976789 0.4835092 0.72829567 0.1291655 0.09364128 0.5811218 0.08068333 0.12905 0.056850 -0.072200 0.99284725 0.02303089 FALSE TRUE
ENST00000546744 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding retained_intron 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 0.4296412 1.2052656 0.08365798 0.3129229 0.08365798 -3.6977259 0.10230000 0.29830 0.008600 -0.289700 0.02303089 0.02303089 FALSE TRUE
ENST00000547672 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding protein_coding 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 0.2767348 0.0000000 0.68950248 0.0000000 0.42035845 6.1282573 0.02752500 0.00000 0.064675 0.064675 0.99284725 0.02303089 FALSE FALSE
ENST00000548945 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding protein_coding_CDS_not_defined 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 4.6839554 0.0000000 5.56362218 0.0000000 5.56362218 9.1224714 0.12830833 0.00000 0.180150 0.180150 1.00000000 0.02303089   FALSE
ENST00000549678 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding retained_intron 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 0.3646376 0.0000000 0.85612300 0.0000000 0.85612300 6.4365000 0.03145000 0.00000 0.064100 0.064100 1.00000000 0.02303089 FALSE FALSE
ENST00000692981 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding protein_coding 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 2.1930390 1.0957460 2.59356797 0.1678747 0.06696374 1.2354700 0.25331667 0.27090 0.203575 -0.067325 0.99284725 0.02303089 FALSE TRUE
ENST00000693534 ENSG00000185920 No_inf pgwt_inf PTCH1 protein_coding protein_coding_CDS_not_defined 11.97777 4.012099 15.86297 0.401467 5.084199 1.980551 2.3382011 0.4280628 3.82082463 0.4280628 0.08397798 3.1284453 0.24580833 0.12455 0.299475 0.174925 0.76985097 0.02303089 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000185920 E001 0.7197539 0.0156082876 0.9355259178 0.982275074 9 95442980 95443148 169 - 0.223 0.234 0.094
ENSG00000185920 E002 0.9140359 0.1031448151 0.0457771169 0.235180880 9 95443149 95443411 263 - 0.369 0.000 -14.212
ENSG00000185920 E003 0.0000000       9 95443412 95443424 13 -      
ENSG00000185920 E004 0.0000000       9 95443425 95443430 6 -      
ENSG00000185920 E005 28.8621708 0.0005905232 0.7236493819 0.898647970 9 95443431 95444161 731 - 1.449 1.466 0.058
ENSG00000185920 E006 1.6832595 0.0241294598 0.7613823686 0.915355553 9 95444162 95444216 55 - 0.399 0.445 0.246
ENSG00000185920 E007 69.6018406 0.0002314315 0.1453132772 0.440982143 9 95444217 95446391 2175 - 1.813 1.856 0.146
ENSG00000185920 E008 0.1308632 0.0122853680 0.2337153293   9 95446392 95446910 519 - 0.000 0.133 12.479
ENSG00000185920 E009 16.3210092 0.0214631513 0.6084651393 0.841807104 9 95446911 95447451 541 - 1.237 1.185 -0.184
ENSG00000185920 E010 8.5006723 0.0027041534 0.0003478567 0.007949342 9 95449069 95449323 255 - 1.063 0.661 -1.561
ENSG00000185920 E011 0.6404355 0.0152668024 0.0281339624 0.177673035 9 95449324 95449840 517 - 0.067 0.386 3.094
ENSG00000185920 E012 5.7465344 0.0028580463 0.0341061054 0.198874858 9 95449841 95449940 100 - 0.887 0.625 -1.058
ENSG00000185920 E013 0.1316618 0.0122675098 0.2338452316   9 95449941 95450123 183 - 0.000 0.133 12.479
ENSG00000185920 E014 0.0000000       9 95450124 95450139 16 -      
ENSG00000185920 E015 2.6473433 0.0069118514 0.6516544463 0.863654546 9 95450140 95453477 3338 - 0.524 0.587 0.287
ENSG00000185920 E016 6.1655828 0.0024747573 0.2626711351 0.590679031 9 95453478 95453620 143 - 0.792 0.911 0.462
ENSG00000185920 E017 3.1840009 0.1122646103 0.3981030208 0.710209260 9 95456276 95456406 131 - 0.655 0.498 -0.713
ENSG00000185920 E018 1.0613487 0.0210853376 0.5326302431 0.800407889 9 95456407 95456413 7 - 0.337 0.234 -0.713
ENSG00000185920 E019 6.1440128 0.0035622715 0.1677255061 0.474321215 9 95458013 95458293 281 - 0.887 0.724 -0.643
ENSG00000185920 E020 3.6152275 0.0475037579 0.5892925513 0.832164044 9 95459600 95459783 184 - 0.622 0.693 0.305
ENSG00000185920 E021 0.0000000       9 95459903 95459955 53 -      
ENSG00000185920 E022 3.5989813 0.0075589367 0.8582203353 0.954285215 9 95461856 95461944 89 - 0.639 0.661 0.094
ENSG00000185920 E023 2.3545386 0.0080463990 0.2431983213 0.569443635 9 95461945 95461998 54 - 0.566 0.386 -0.906
ENSG00000185920 E024 3.3686141 0.0044483223 0.6593703961 0.866805429 9 95467116 95467286 171 - 0.604 0.661 0.246
ENSG00000185920 E025 2.6327871 0.0279216408 0.9928269456 1.000000000 9 95467287 95467425 139 - 0.546 0.545 -0.005
ENSG00000185920 E026 3.6772116 0.0053861297 0.4708261544 0.761723416 9 95468751 95468937 187 - 0.686 0.587 -0.429
ENSG00000185920 E027 5.6208978 0.0025276378 0.9847990422 0.999189770 9 95468938 95469153 216 - 0.804 0.804 0.001
ENSG00000185920 E028 0.0000000       9 95469154 95469227 74 -      
ENSG00000185920 E029 2.4366920 0.0118297454 0.2262759374 0.550747932 9 95469813 95469931 119 - 0.454 0.625 0.805
ENSG00000185920 E030 0.0000000       9 95474012 95474143 132 -      
ENSG00000185920 E031 2.2888071 0.0059358968 0.6422763614 0.858773466 9 95476034 95476159 126 - 0.479 0.545 0.317
ENSG00000185920 E032 2.1068485 0.0069576451 0.1473084540 0.443915565 9 95476759 95476857 99 - 0.546 0.317 -1.228
ENSG00000185920 E033 2.3356695 0.0060980965 0.0867884316 0.337527522 9 95477547 95477702 156 - 0.585 0.317 -1.408
ENSG00000185920 E034 2.5174936 0.0054637571 0.8799026073 0.961992541 9 95478055 95478186 132 - 0.524 0.545 0.094
ENSG00000185920 E035 3.3983601 0.0084534731 0.2278018215 0.552902684 9 95479000 95479147 148 - 0.566 0.724 0.679
ENSG00000185920 E036 0.0000000       9 95479856 95479968 113 -      
ENSG00000185920 E037 1.7795914 0.0131026119 0.6723216963 0.873483726 9 95479969 95479995 27 - 0.454 0.386 -0.365
ENSG00000185920 E038 2.0075827 0.0164259200 0.4655837510 0.757885375 9 95479996 95480060 65 - 0.502 0.386 -0.606
ENSG00000185920 E039 1.1583256 0.0132242469 0.1082199776 0.379897621 9 95480061 95480090 30 - 0.399 0.133 -2.076
ENSG00000185920 E040 2.0422172 0.0598904163 0.7581177173 0.914095594 9 95480390 95480439 50 - 0.454 0.498 0.220
ENSG00000185920 E041 2.4537975 0.0063231198 0.0942221163 0.352915774 9 95480440 95480538 99 - 0.427 0.661 1.094
ENSG00000185920 E042 0.7533142 0.0134416197 0.0824826666 0.328359568 9 95480539 95480543 5 - 0.126 0.386 2.094
ENSG00000185920 E043 0.8679090 0.0123771770 0.1709654530 0.479064241 9 95480544 95480588 45 - 0.177 0.386 1.509
ENSG00000185920 E044 0.1138060 0.0111708053 1.0000000000   9 95481829 95481948 120 - 0.067 0.000 -11.886
ENSG00000185920 E045 0.7185351 0.0145445247 0.9353114653 0.982275074 9 95481949 95481965 17 - 0.223 0.234 0.094
ENSG00000185920 E046 0.8327102 0.0129210316 0.8554622884 0.953158164 9 95481966 95481970 5 - 0.264 0.234 -0.228
ENSG00000185920 E047 1.7627357 0.0305375230 0.3291724695 0.653013089 9 95481971 95482040 70 - 0.479 0.317 -0.906
ENSG00000185920 E048 1.5174148 0.0135401113 0.1811198164 0.494010065 9 95482134 95482203 70 - 0.454 0.234 -1.365
ENSG00000185920 E049 0.0000000       9 95482204 95482238 35 -      
ENSG00000185920 E050 0.6040845 0.0162841604 0.7005490322   9 95482239 95484309 2071 - 0.177 0.234 0.509
ENSG00000185920 E051 1.7782152 0.1386577885 0.7949382329 0.929333195 9 95485685 95485823 139 - 0.454 0.386 -0.365
ENSG00000185920 E052 0.9457273 0.1184313777 0.7297537963 0.901432776 9 95485824 95485874 51 - 0.302 0.234 -0.490
ENSG00000185920 E053 0.1141751 0.0111957034 1.0000000000   9 95494262 95494401 140 - 0.067 0.000 -11.886
ENSG00000185920 E054 0.0000000       9 95503300 95503346 47 -      
ENSG00000185920 E055 0.0000000       9 95505794 95505878 85 -      
ENSG00000185920 E056 0.0000000       9 95506407 95506599 193 -      
ENSG00000185920 E057 0.0000000       9 95506600 95506665 66 -      
ENSG00000185920 E058 0.0000000       9 95506937 95507228 292 -      
ENSG00000185920 E059 0.0000000       9 95507229 95507231 3 -      
ENSG00000185920 E060 0.0000000       9 95507232 95507417 186 -      
ENSG00000185920 E061 0.8678553 0.0140124920 0.1713486905 0.479682360 9 95507934 95507950 17 - 0.177 0.386 1.509
ENSG00000185920 E062 1.8154514 0.0078988131 0.5064569031 0.784590098 9 95507951 95508160 210 - 0.399 0.498 0.509
ENSG00000185920 E063 3.4548981 0.0071226939 0.0190173661 0.139524188 9 95508161 95509266 1106 - 0.502 0.804 1.301
ENSG00000185920 E064 0.2633236 0.1821227290 0.0935278721   9 95516469 95516622 154 - 0.000 0.234 13.134
ENSG00000185920 E065 0.0000000       9 95516623 95517057 435 -      

Help

Please Click HERE to learn more details about the results from DEXseq.