ENSG00000187555

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381886 ENSG00000187555 No_inf pgwt_inf USP7 protein_coding protein_coding 59.77422 60.6156 54.59631 4.361733 1.378518 -0.1508595 3.602699 0.000000 2.7967287 0.0000000 1.7861815 8.1327458 0.05853333 0.00000 0.049900 0.049900 0.9695191240 0.0002328543 FALSE TRUE
ENST00000563961 ENSG00000187555 No_inf pgwt_inf USP7 protein_coding nonsense_mediated_decay 59.77422 60.6156 54.59631 4.361733 1.378518 -0.1508595 3.754238 1.727682 3.3703207 0.9986102 0.4152633 0.9599961 0.06228333 0.03000 0.061350 0.031350 0.9737145132 0.0002328543 FALSE TRUE
ENST00000565883 ENSG00000187555 No_inf pgwt_inf USP7 protein_coding retained_intron 59.77422 60.6156 54.59631 4.361733 1.378518 -0.1508595 2.938498 6.283404 0.0000000 2.1914712 0.0000000 -9.2976968 0.04545000 0.09920 0.000000 -0.099200 0.0002328543 0.0002328543 FALSE FALSE
ENST00000567113 ENSG00000187555 No_inf pgwt_inf USP7 protein_coding retained_intron 59.77422 60.6156 54.59631 4.361733 1.378518 -0.1508595 1.559698 4.161887 0.5172053 2.6928451 0.5172053 -2.9842634 0.02744167 0.07325 0.009075 -0.064175 0.9928472467 0.0002328543   FALSE
MSTRG.10611.3 ENSG00000187555 No_inf pgwt_inf USP7 protein_coding   59.77422 60.6156 54.59631 4.361733 1.378518 -0.1508595 36.025069 32.514395 37.3613189 0.1365480 1.1464641 0.2004093 0.61026667 0.54425 0.686450 0.142200 0.9928472467 0.0002328543 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000187555 E001 12.6797313 4.194893e-02 0.388666335 0.70239757 16 8892097 8892771 675 - 1.080 1.187 0.385
ENSG00000187555 E002 209.6004167 8.883279e-05 0.001076754 0.01896000 16 8892772 8893787 1016 - 2.290 2.356 0.220
ENSG00000187555 E003 77.3726694 4.323450e-04 0.214935580 0.53719728 16 8893788 8893939 152 - 1.872 1.915 0.145
ENSG00000187555 E004 104.8770519 1.522670e-04 0.738356018 0.90529061 16 8893940 8894104 165 - 2.020 2.030 0.033
ENSG00000187555 E005 75.2225186 2.159690e-03 0.239821370 0.56557784 16 8894550 8894640 91 - 1.904 1.858 -0.154
ENSG00000187555 E006 53.5366781 1.314372e-03 0.502520840 0.78242087 16 8894784 8894855 72 - 1.751 1.722 -0.098
ENSG00000187555 E007 31.2715076 4.459435e-04 0.563370794 0.81774074 16 8895031 8895044 14 - 1.524 1.493 -0.105
ENSG00000187555 E008 30.6018015 4.546592e-04 0.911165741 0.97370539 16 8895045 8895058 14 - 1.503 1.497 -0.020
ENSG00000187555 E009 37.9538202 3.718218e-04 0.357818945 0.67777104 16 8895059 8895083 25 - 1.568 1.613 0.152
ENSG00000187555 E010 50.0450583 2.622677e-04 0.383266864 0.69908674 16 8895084 8895150 67 - 1.689 1.726 0.125
ENSG00000187555 E011 63.6399329 2.283388e-04 0.795501232 0.92956149 16 8895642 8895741 100 - 1.815 1.806 -0.032
ENSG00000187555 E012 51.2838496 2.790217e-04 0.787600826 0.92637626 16 8896999 8897063 65 - 1.713 1.724 0.039
ENSG00000187555 E013 37.8559361 3.653754e-04 0.811385279 0.93574328 16 8897064 8897099 36 - 1.584 1.595 0.040
ENSG00000187555 E014 0.8494693 1.912977e-01 0.925966195 0.97925855 16 8897100 8897254 155 - 0.279 0.255 -0.170
ENSG00000187555 E015 42.4371152 3.355577e-04 0.507453434 0.78520091 16 8898360 8898437 78 - 1.623 1.653 0.104
ENSG00000187555 E016 1.0486416 1.210451e-01 0.002894430 0.03980665 16 8898438 8898530 93 - 0.000 0.496 12.860
ENSG00000187555 E017 45.1415433 3.480461e-04 0.945772477 0.98636261 16 8898531 8898593 63 - 1.663 1.666 0.011
ENSG00000187555 E018 41.4353033 3.391013e-04 0.599388037 0.83738894 16 8898594 8898639 46 - 1.615 1.640 0.083
ENSG00000187555 E019 0.7519246 2.502852e-01 0.374134278 0.69180956 16 8898640 8898720 81 - 0.161 0.315 1.245
ENSG00000187555 E020 22.3800755 2.199609e-02 0.770274241 0.91955407 16 8899121 8899149 29 - 1.354 1.384 0.103
ENSG00000187555 E021 24.4901012 1.457014e-02 0.550269567 0.81098307 16 8899150 8899174 25 - 1.383 1.429 0.159
ENSG00000187555 E022 20.8722932 9.685959e-03 0.926598114 0.97951707 16 8899175 8899188 14 - 1.336 1.344 0.025
ENSG00000187555 E023 1.4112212 3.999764e-02 0.019054412 0.13971305 16 8899307 8899579 273 - 0.161 0.531 2.415
ENSG00000187555 E024 0.6559052 1.528335e-02 0.012513029 0.10757355 16 8899580 8899603 24 - 0.000 0.368 12.869
ENSG00000187555 E025 54.1363449 3.480050e-04 0.228079139 0.55312717 16 8899604 8899757 154 - 1.716 1.766 0.167
ENSG00000187555 E026 3.1097600 4.691232e-03 0.159417504 0.46204617 16 8899758 8900131 374 - 0.512 0.699 0.830
ENSG00000187555 E027 45.9726870 2.348908e-03 0.203049558 0.52221737 16 8900530 8900630 101 - 1.641 1.702 0.207
ENSG00000187555 E028 2.4379374 6.603007e-03 0.945005694 0.98613089 16 8900631 8900920 290 - 0.541 0.531 -0.044
ENSG00000187555 E029 40.7403375 6.672995e-04 0.476799847 0.76556222 16 8900990 8901057 68 - 1.603 1.637 0.115
ENSG00000187555 E030 42.0144355 3.569110e-04 0.280782254 0.60892832 16 8901142 8901234 93 - 1.608 1.658 0.169
ENSG00000187555 E031 1.6214986 8.068880e-03 0.260077962 0.58766062 16 8901933 8902081 149 - 0.327 0.496 0.923
ENSG00000187555 E032 33.1260299 4.206771e-04 0.631328147 0.85266082 16 8902082 8902138 57 - 1.521 1.545 0.085
ENSG00000187555 E033 17.8839226 8.606704e-04 0.493380539 0.77624392 16 8902139 8902142 4 - 1.252 1.299 0.166
ENSG00000187555 E034 29.4145191 6.188192e-04 0.296318293 0.62426136 16 8902143 8902187 45 - 1.454 1.511 0.197
ENSG00000187555 E035 1.7362727 8.010898e-02 0.462887567 0.75625621 16 8902188 8902380 193 - 0.371 0.496 0.660
ENSG00000187555 E036 36.0147326 1.011110e-02 0.369155556 0.68753215 16 8902381 8902482 102 - 1.541 1.595 0.186
ENSG00000187555 E037 48.1200959 6.666880e-03 0.159193482 0.46172459 16 8903268 8903402 135 - 1.728 1.650 -0.261
ENSG00000187555 E038 34.3989878 5.357751e-04 0.371639437 0.68991646 16 8904435 8904504 70 - 1.571 1.525 -0.155
ENSG00000187555 E039 18.3739157 1.269416e-02 0.660834444 0.86758739 16 8904505 8904524 20 - 1.304 1.269 -0.120
ENSG00000187555 E040 21.2159413 8.635534e-03 0.280971368 0.60900074 16 8904525 8904565 41 - 1.383 1.305 -0.271
ENSG00000187555 E041 44.8048134 2.871406e-03 0.607413257 0.84136047 16 8905187 8905331 145 - 1.673 1.648 -0.086
ENSG00000187555 E042 46.4797748 8.399512e-03 0.613195078 0.84412711 16 8906426 8906582 157 - 1.691 1.661 -0.104
ENSG00000187555 E043 35.9512455 4.054056e-04 0.813921478 0.93664696 16 8908341 8908450 110 - 1.573 1.562 -0.040
ENSG00000187555 E044 33.5840076 4.298788e-03 0.824918159 0.94076361 16 8910745 8910827 83 - 1.532 1.546 0.045
ENSG00000187555 E045 27.0725065 5.624738e-04 0.934338618 0.98183420 16 8915254 8915344 91 - 1.450 1.446 -0.016
ENSG00000187555 E046 23.9390363 7.927147e-04 0.464594333 0.75736191 16 8915445 8915525 81 - 1.418 1.374 -0.153
ENSG00000187555 E047 19.3111875 7.798887e-04 0.450771147 0.74829010 16 8916502 8916556 55 - 1.332 1.282 -0.175
ENSG00000187555 E048 29.6905009 1.355626e-03 0.165377436 0.47108964 16 8917026 8917156 131 - 1.524 1.446 -0.267
ENSG00000187555 E049 24.4412995 7.942130e-04 0.007954703 0.07987202 16 8919031 8919139 109 - 1.477 1.316 -0.557
ENSG00000187555 E050 15.3267270 1.382705e-03 0.637880622 0.85617382 16 8920359 8920404 46 - 1.230 1.195 -0.123
ENSG00000187555 E051 13.2789798 2.003005e-02 0.198557984 0.51631884 16 8920405 8920442 38 - 1.212 1.086 -0.450
ENSG00000187555 E052 9.3506383 2.463100e-03 0.028600821 0.17896077 16 8920443 8920447 5 - 1.104 0.899 -0.755
ENSG00000187555 E053 9.1214486 3.978665e-03 0.047692985 0.24083489 16 8921157 8921159 3 - 1.088 0.899 -0.698
ENSG00000187555 E054 12.6023733 1.594737e-02 0.045667210 0.23490797 16 8921160 8921176 17 - 1.218 1.025 -0.693
ENSG00000187555 E055 24.3769132 1.421392e-03 0.032560728 0.19319535 16 8921177 8921295 119 - 1.464 1.333 -0.454
ENSG00000187555 E056 23.2617566 1.071063e-03 0.157784627 0.45983390 16 8923215 8923306 92 - 1.426 1.338 -0.302
ENSG00000187555 E057 15.9968138 8.568865e-04 0.264490686 0.59260595 16 8923307 8923353 47 - 1.268 1.187 -0.285
ENSG00000187555 E058 11.8557138 5.435464e-03 0.261082586 0.58875282 16 8923354 8923413 60 - 1.154 1.057 -0.352
ENSG00000187555 E059 0.5888325 1.536767e-02 0.238216391   16 8929369 8929543 175 - 0.279 0.103 -1.755
ENSG00000187555 E060 14.5245508 1.285518e-03 0.208741827 0.52944427 16 8930293 8930397 105 - 1.235 1.140 -0.340
ENSG00000187555 E061 0.1308632 1.228184e-02 0.453751950   16 8931940 8932053 114 - 0.000 0.103 10.647
ENSG00000187555 E062 0.0000000       16 8935643 8935758 116 -      
ENSG00000187555 E063 0.0000000       16 8935801 8935856 56 -      
ENSG00000187555 E064 0.0000000       16 8936583 8936729 147 -      
ENSG00000187555 E065 0.1311489 1.228759e-02 0.453761850   16 8949554 8949653 100 - 0.000 0.103 10.647
ENSG00000187555 E066 0.0000000       16 8956308 8956380 73 -      
ENSG00000187555 E067 0.0000000       16 8962476 8962612 137 -      
ENSG00000187555 E068 16.7086923 1.097316e-03 0.013083716 0.11042324 16 8963207 8963906 700 - 1.327 1.148 -0.632
ENSG00000187555 E069 0.0000000       16 8964394 8964514 121 -      
ENSG00000187555 E070 0.0000000       16 8975094 8975328 235 -      

Help

Please Click HERE to learn more details about the results from DEXseq.