ENSG00000187815

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372705 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding protein_coding 49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 15.969756 14.6304781 13.692083 1.9839182 1.1976024 -0.09556745 0.32458333 0.356350 0.256525 -0.099825 0.992847247 0.009776889 FALSE TRUE
ENST00000372706 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding protein_coding 49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 4.272839 2.7664900 10.052028 2.7664900 5.9171187 1.85758706 0.08644167 0.070725 0.188600 0.117875 0.992847247 0.009776889 FALSE TRUE
ENST00000482712 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding protein_coding_CDS_not_defined 49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 7.339182 9.3270666 6.196617 1.6918420 1.0597994 -0.58916231 0.15306667 0.225975 0.115500 -0.110475 0.964475350 0.009776889   FALSE
MSTRG.783.1 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 2.613587 0.1682371 7.232009 0.1682371 0.5779308 5.34452045 0.04962500 0.004800 0.136250 0.131450 0.009776889 0.009776889 FALSE TRUE
MSTRG.783.2 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 1.014563 2.3113377 0.000000 1.3345664 0.0000000 -7.85881262 0.02372500 0.055625 0.000000 -0.055625 0.952491949 0.009776889 FALSE TRUE
MSTRG.783.3 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 2.778651 0.0000000 0.000000 0.0000000 0.0000000 0.00000000 0.05312500 0.000000 0.000000 0.000000   0.009776889 FALSE TRUE
MSTRG.783.4 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 3.448122 2.8734616 5.313270 1.6592982 0.4740570 0.88451085 0.07041667 0.073725 0.099900 0.026175 0.992847247 0.009776889 FALSE TRUE
MSTRG.783.5 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 5.521390 5.1811128 0.000000 1.8887415 0.0000000 -9.01990002 0.10929167 0.126300 0.000000 -0.126300 0.169672822 0.009776889 FALSE TRUE
MSTRG.783.6 ENSG00000187815 No_inf pgwt_inf ZFP69 protein_coding   49.33444 40.64708 53.2824 2.212486 1.287719 0.3904233 5.488645 2.3067749 10.796391 1.5717219 6.4248124 2.22169505 0.11225833 0.062050 0.203275 0.141225 1.000000000 0.009776889 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000187815 E001 0.6852023 0.2353298281 0.0680028790 0.295514148 1 40477149 40477222 74 + 0.343 0.000 -10.663
ENSG00000187815 E002 0.4737217 0.0304632584 0.5487860382   1 40477223 40477229 7 + 0.204 0.114 -1.004
ENSG00000187815 E003 0.5878968 0.0153019756 0.3485677441   1 40477230 40477246 17 + 0.255 0.114 -1.419
ENSG00000187815 E004 0.4911481 0.0158264545 0.6942890053   1 40477247 40477289 43 + 0.146 0.204 0.581
ENSG00000187815 E005 1.4566000 0.0105747830 0.9182448116 0.976109735 1 40477290 40477316 27 + 0.380 0.397 0.095
ENSG00000187815 E006 26.2964627 0.0046778742 0.0127068586 0.108424697 1 40477317 40477629 313 + 1.495 1.336 -0.549
ENSG00000187815 E007 44.0556252 0.0003150129 0.0001030217 0.003029923 1 40477630 40477894 265 + 1.718 1.542 -0.599
ENSG00000187815 E008 34.7424753 0.0013106134 0.0005631202 0.011524210 1 40477895 40479015 1121 + 1.463 1.642 0.611
ENSG00000187815 E009 6.5630226 0.0740955193 0.3537270023 0.673854848 1 40479016 40479035 20 + 0.935 0.785 -0.579
ENSG00000187815 E010 60.8132090 0.0002474027 0.0905688804 0.345422773 1 40479036 40479332 297 + 1.813 1.751 -0.210
ENSG00000187815 E011 37.1996913 0.0005200912 0.0280974982 0.177527231 1 40479333 40479488 156 + 1.622 1.515 -0.364
ENSG00000187815 E012 29.0946351 0.0006265810 0.5186458145 0.791840836 1 40481763 40481854 92 + 1.489 1.456 -0.115
ENSG00000187815 E013 27.4595105 0.0005141737 0.8638119091 0.956561389 1 40489088 40489145 58 + 1.454 1.446 -0.026
ENSG00000187815 E014 25.9232191 0.0005772193 0.2426953054 0.568943386 1 40489146 40489214 69 + 1.395 1.465 0.240
ENSG00000187815 E015 5.5093448 0.0921739695 0.4787423449 0.766744588 1 40489526 40489528 3 + 0.749 0.880 0.516
ENSG00000187815 E016 36.3166180 0.0003897109 0.9620589127 0.990974629 1 40489529 40489624 96 + 1.566 1.571 0.016
ENSG00000187815 E017 15.1134436 0.0336812723 0.0004836977 0.010308140 1 40490780 40491156 377 + 1.000 1.376 1.337
ENSG00000187815 E018 389.3845807 0.0001056122 0.0677621680 0.294854299 1 40494921 40496667 1747 + 2.578 2.600 0.074
ENSG00000187815 E019 0.2623781 0.0160432390 0.1337747528   1 40496761 40496787 27 + 0.000 0.204 11.581

Help

Please Click HERE to learn more details about the results from DEXseq.