ENSG00000189091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302516 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding protein_coding 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 11.148199 6.992479 13.344539 0.4238462 0.2298909 0.9313925 0.16742500 0.170100 0.166200 -0.003900 1.000000000 0.002536269 FALSE  
ENST00000563739 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 9.933940 5.138094 12.267159 1.3562786 2.2752132 1.2538664 0.14544167 0.126875 0.154975 0.028100 0.993236612 0.002536269 FALSE  
ENST00000566095 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding protein_coding 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 2.917764 0.000000 4.110565 0.0000000 0.4464917 8.6866984 0.03685000 0.000000 0.050475 0.050475 0.002536269 0.002536269 FALSE  
ENST00000567635 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding nonsense_mediated_decay 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 3.756247 4.466513 4.344459 1.8659187 1.9335540 -0.0398818 0.06511667 0.105900 0.057100 -0.048800 0.992847247 0.002536269    
ENST00000568539 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 18.777031 12.156818 22.592978 1.5576219 5.5803808 0.8935610 0.27924167 0.291850 0.270925 -0.020925 1.000000000 0.002536269 FALSE  
ENST00000572365 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding retained_intron 67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 10.091071 3.536738 13.126646 1.2699671 0.8165705 1.8890321 0.14010833 0.084675 0.164100 0.079425 0.992847247 0.002536269 FALSE  
MSTRG.11430.11 ENSG00000189091 No_inf pgwt_inf SF3B3 protein_coding   67.11694 41.43282 80.91656 1.433602 3.962862 0.9654912 4.864846 3.908514 5.578138 0.5532565 0.1695808 0.5120609 0.07639167 0.093800 0.069775 -0.024025 0.992847247 0.002536269 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000189091 E001 0.2281253 1.532435e-02 0.51873464   16 70523791 70523812 22 + 0.135 0.000 -10.094
ENSG00000189091 E002 0.2281253 1.532435e-02 0.51873464   16 70523813 70523815 3 + 0.135 0.000 -12.597
ENSG00000189091 E003 6.8585214 3.712348e-02 0.11580973 0.39346381 16 70523816 70523892 77 + 0.800 0.993 0.736
ENSG00000189091 E004 8.6755930 6.939827e-02 0.19713843 0.51405363 16 70523893 70523928 36 + 0.901 1.072 0.636
ENSG00000189091 E005 0.2457437 1.615363e-02 0.64943512   16 70523929 70524055 127 + 0.073 0.123 0.839
ENSG00000189091 E006 0.3769827 1.686089e-02 0.28538556   16 70524550 70524863 314 + 0.073 0.219 1.839
ENSG00000189091 E007 0.9306098 1.489214e-02 0.14341217 0.43806770 16 70524864 70525017 154 + 0.358 0.123 -1.968
ENSG00000189091 E008 16.7895307 1.007616e-03 0.45952997 0.75410005 16 70526587 70526726 140 + 1.219 1.271 0.185
ENSG00000189091 E009 0.0000000       16 70526901 70527014 114 +      
ENSG00000189091 E010 36.2575452 5.241759e-03 0.26409878 0.59211457 16 70528873 70529199 327 + 1.586 1.520 -0.225
ENSG00000189091 E011 29.9499962 1.707993e-03 0.40308662 0.71353149 16 70530745 70530917 173 + 1.499 1.450 -0.169
ENSG00000189091 E012 24.8605231 2.969032e-03 0.47052959 0.76148440 16 70532479 70532620 142 + 1.385 1.429 0.154
ENSG00000189091 E013 21.3527959 6.773412e-04 0.08878287 0.34185301 16 70535308 70535420 113 + 1.294 1.402 0.376
ENSG00000189091 E014 16.4684113 8.882134e-04 0.26576970 0.59389839 16 70538323 70538394 72 + 1.199 1.279 0.281
ENSG00000189091 E015 18.3738883 4.264003e-03 0.78655401 0.92594820 16 70538395 70538460 66 + 1.286 1.264 -0.077
ENSG00000189091 E016 20.3638210 8.028630e-04 0.43759713 0.73925236 16 70539104 70539207 104 + 1.340 1.286 -0.186
ENSG00000189091 E017 15.5666090 8.641750e-04 0.04377942 0.22996976 16 70541669 70541738 70 + 1.265 1.107 -0.561
ENSG00000189091 E018 20.2478686 6.734971e-04 0.46938350 0.76059010 16 70541739 70541834 96 + 1.336 1.286 -0.173
ENSG00000189091 E019 19.4335898 8.347728e-04 0.62453028 0.84977097 16 70544438 70544533 96 + 1.314 1.279 -0.121
ENSG00000189091 E020 13.8416056 1.039607e-03 0.20368182 0.52275445 16 70548370 70548442 73 + 1.199 1.096 -0.371
ENSG00000189091 E021 0.8330621 2.617487e-02 0.69124532 0.88242893 16 70548443 70548512 70 + 0.282 0.219 -0.482
ENSG00000189091 E022 1.7797857 1.301035e-01 0.52683856 0.79684745 16 70550203 70550567 365 + 0.479 0.364 -0.620
ENSG00000189091 E023 0.8677591 6.723751e-02 0.28263442 0.61040246 16 70550568 70550649 82 + 0.190 0.364 1.254
ENSG00000189091 E024 1.7358349 2.345650e-02 0.11755945 0.39684351 16 70550650 70550678 29 + 0.322 0.559 1.255
ENSG00000189091 E025 1.1126641 4.889104e-02 0.25481428 0.58175945 16 70554106 70554445 340 + 0.239 0.421 1.161
ENSG00000189091 E026 23.0454277 5.979165e-04 0.68095647 0.87753690 16 70554446 70554597 152 + 1.381 1.354 -0.093
ENSG00000189091 E027 36.5491127 4.045803e-04 0.32434589 0.64865239 16 70555051 70555206 156 + 1.584 1.532 -0.175
ENSG00000189091 E028 45.9143562 1.355553e-03 0.34839517 0.66922327 16 70556179 70556334 156 + 1.678 1.633 -0.155
ENSG00000189091 E029 0.3941868 3.078205e-02 0.03202210   16 70556335 70556597 263 + 0.000 0.297 13.213
ENSG00000189091 E030 42.4667269 3.421738e-04 0.02124657 0.14953179 16 70556886 70557029 144 + 1.668 1.557 -0.379
ENSG00000189091 E031 0.3427201 1.567333e-02 0.27502410   16 70560350 70560468 119 + 0.190 0.000 -13.150
ENSG00000189091 E032 42.4501147 6.500152e-03 0.47653721 0.76556222 16 70560469 70560591 123 + 1.644 1.602 -0.142
ENSG00000189091 E033 0.0000000       16 70561349 70561629 281 +      
ENSG00000189091 E034 47.4200889 2.515674e-03 0.85151931 0.95145767 16 70561630 70561784 155 + 1.672 1.680 0.028
ENSG00000189091 E035 0.1138060 1.114766e-02 1.00000000   16 70563729 70563875 147 + 0.073 0.000 -11.672
ENSG00000189091 E036 47.0036000 3.128833e-04 0.56735353 0.81948493 16 70563876 70564050 175 + 1.661 1.686 0.083
ENSG00000189091 E037 48.6376783 4.711867e-04 0.67975316 0.87685894 16 70565065 70565270 206 + 1.693 1.674 -0.065
ENSG00000189091 E038 42.9644653 6.055819e-03 0.24989647 0.57665742 16 70565368 70565524 157 + 1.658 1.591 -0.228
ENSG00000189091 E039 0.2449549 1.613994e-02 0.64953755   16 70565525 70565720 196 + 0.073 0.123 0.839
ENSG00000189091 E040 48.4914969 3.146127e-04 0.10740320 0.37855930 16 70567411 70567536 126 + 1.656 1.725 0.233
ENSG00000189091 E041 0.2625250 1.605054e-02 0.09847158   16 70567537 70567541 5 + 0.000 0.219 12.778
ENSG00000189091 E042 75.0391233 2.380190e-04 0.55382120 0.81309077 16 70568283 70568495 213 + 1.863 1.883 0.067
ENSG00000189091 E043 34.9789722 4.822525e-03 0.89699029 0.96915243 16 70569043 70569141 99 + 1.549 1.541 -0.029
ENSG00000189091 E044 0.4901369 1.100947e-01 0.57571136   16 70569915 70570005 91 + 0.135 0.219 0.840
ENSG00000189091 E045 51.4349257 3.190149e-04 0.67273207 0.87348373 16 70570006 70570149 144 + 1.703 1.719 0.057
ENSG00000189091 E046 44.9085440 1.030609e-02 0.31372591 0.63966721 16 70571095 70571199 105 + 1.675 1.612 -0.213
ENSG00000189091 E047 212.8442746 7.883095e-05 0.01111246 0.09961436 16 70571673 70576300 4628 + 2.300 2.348 0.161
ENSG00000189091 E048 1.0956621 1.159406e-02 0.59838953 0.83687507 16 70576301 70576348 48 + 0.282 0.364 0.518
ENSG00000189091 E049 9.9718431 4.242531e-02 0.88096520 0.96237652 16 70576349 70577317 969 + 1.037 1.021 -0.057
ENSG00000189091 E050 2.8774054 6.279731e-03 0.80355163 0.93278203 16 70577318 70577670 353 + 0.594 0.559 -0.161

Help

Please Click HERE to learn more details about the results from DEXseq.