ENSG00000197324

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359591 ENSG00000197324 No_inf pgwt_inf LRP10 protein_coding protein_coding 94.30971 77.86056 103.1556 0.6028343 1.279746 0.4058126 72.38437 76.3841007 69.47378 0.4903636 0.5679058 -0.1367849 0.7848417 0.981275 0.673750 -0.307525 0.001018907 0.001018907 FALSE TRUE
ENST00000553002 ENSG00000197324 No_inf pgwt_inf LRP10 protein_coding retained_intron 94.30971 77.86056 103.1556 0.6028343 1.279746 0.4058126 21.18348 0.7885519 33.01728 0.7885519 1.3268994 5.3701279 0.2071833 0.009925 0.319775 0.309850 0.006423968 0.001018907 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000197324 E001 0.8691997 5.716415e-01 9.494543e-01 9.872048e-01 14 22871740 22871773 34 + 0.238 0.299 0.440
ENSG00000197324 E002 1.4914284 5.107573e-02 5.794607e-01 8.262269e-01 14 22871774 22871781 8 + 0.345 0.436 0.511
ENSG00000197324 E003 198.4303642 8.432248e-05 3.376889e-14 6.356935e-12 14 22871782 22872303 522 + 2.377 2.216 -0.536
ENSG00000197324 E004 54.5161416 2.810437e-04 2.873630e-03 3.961296e-02 14 22872304 22872337 34 + 1.804 1.683 -0.409
ENSG00000197324 E005 55.7842189 2.549669e-04 5.752418e-03 6.384547e-02 14 22872738 22872782 45 + 1.809 1.698 -0.373
ENSG00000197324 E006 0.7694893 1.425027e-02 8.991793e-02 3.441765e-01 14 22873085 22873310 226 + 0.094 0.349 2.347
ENSG00000197324 E007 89.7397795 1.761384e-04 1.095152e-04 3.180374e-03 14 22873311 22873446 136 + 2.018 1.895 -0.412
ENSG00000197324 E008 69.3162676 2.868197e-04 2.963524e-06 1.464820e-04 14 22875055 22875135 81 + 1.928 1.758 -0.572
ENSG00000197324 E009 95.0320023 1.430326e-04 2.114543e-07 1.380721e-05 14 22875136 22875245 110 + 2.059 1.899 -0.537
ENSG00000197324 E010 109.7517255 1.365630e-04 1.248650e-05 5.134455e-04 14 22875355 22875465 111 + 2.105 1.980 -0.419
ENSG00000197324 E011 586.0908157 4.013687e-05 3.994666e-14 7.466931e-12 14 22875466 22876299 834 + 2.812 2.724 -0.292
ENSG00000197324 E012 129.1922458 1.256319e-04 3.856668e-03 4.840850e-02 14 22876300 22876372 73 + 2.152 2.077 -0.253
ENSG00000197324 E013 101.1889598 1.435712e-04 9.598923e-06 4.106111e-04 14 22876689 22876716 28 + 2.074 1.942 -0.442
ENSG00000197324 E014 171.5597651 9.367294e-05 4.195714e-04 9.203871e-03 14 22876717 22876818 102 + 2.277 2.197 -0.267
ENSG00000197324 E015 184.9889658 1.204699e-04 4.420190e-03 5.332960e-02 14 22876940 22877053 114 + 2.301 2.238 -0.208
ENSG00000197324 E016 354.8020772 5.673206e-05 1.163060e-02 1.024426e-01 14 22877054 22877426 373 + 2.570 2.532 -0.128
ENSG00000197324 E017 239.9390013 9.824328e-05 6.475745e-02 2.871310e-01 14 22877427 22877596 170 + 2.399 2.364 -0.116
ENSG00000197324 E018 572.7503796 6.444395e-05 1.696638e-24 7.322580e-22 14 22877597 22877983 387 + 2.687 2.812 0.416
ENSG00000197324 E019 210.1875659 8.227244e-05 2.052344e-18 6.052817e-16 14 22877984 22879198 1215 + 2.216 2.401 0.616
ENSG00000197324 E020 448.1118416 5.030783e-05 3.519997e-78 1.698751e-74 14 22879199 22881713 2515 + 2.491 2.757 0.886

Help

Please Click HERE to learn more details about the results from DEXseq.