ENSG00000197774

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000561564 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding retained_intron 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 1.5365641 0.0000000 4.6096922 0.0000000 0.9616740 8.8516529 0.11396667 0.000000 0.341900 0.341900 0.0003105358 0.0003105358 FALSE FALSE
ENST00000561903 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding nonsense_mediated_decay 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 0.7331480 0.6860050 1.1615073 0.4011409 0.6716759 0.7511965 0.07052500 0.081250 0.082475 0.001225 1.0000000000 0.0003105358 TRUE TRUE
ENST00000564182 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding nonsense_mediated_decay 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 0.8028239 0.7385135 0.9483275 0.7385135 0.9483275 0.3564905 0.08711667 0.096025 0.067200 -0.028825 1.0000000000 0.0003105358 TRUE FALSE
ENST00000565326 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding retained_intron 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 1.0709891 1.8053919 0.0000000 1.8053919 0.0000000 -7.5041372 0.09946667 0.154175 0.000000 -0.154175 0.9928472467 0.0003105358 FALSE FALSE
ENST00000568449 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding protein_coding 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 1.6220193 1.1653838 2.5405132 0.4318327 0.1761298 1.1176556 0.15790000 0.122825 0.195850 0.073025 0.9928472467 0.0003105358 FALSE TRUE
ENST00000570069 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding retained_intron 9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 2.7982528 2.9414039 3.3417084 0.7641236 0.3676063 0.1834953 0.31270000 0.376025 0.252025 -0.124000 0.9928472467 0.0003105358 FALSE TRUE
MSTRG.10423.4 ENSG00000197774 No_inf pgwt_inf EME2 protein_coding   9.79317 8.809704 13.27132 1.052459 1.006588 0.5905966 1.2293731 1.4730060 0.6695728 1.2871128 0.5205345 -1.1258243 0.15834167 0.169725 0.060525 -0.109200 0.9941503691 0.0003105358 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000197774 E001 1.176283 0.059419164 0.249684017 0.57663261 16 1772810 1773325 516 + 0.407 0.209 -1.335
ENSG00000197774 E002 3.122424 0.004957648 0.732537116 0.90252888 16 1773326 1773474 149 + 0.634 0.577 -0.252
ENSG00000197774 E003 5.540243 0.002602230 0.898004266 0.96953539 16 1773705 1773841 137 + 0.822 0.795 -0.105
ENSG00000197774 E004 4.559809 0.003214060 0.639370414 0.85704547 16 1774260 1774352 93 + 0.768 0.700 -0.278
ENSG00000197774 E005 1.140808 0.010413653 0.004768573 0.05631691 16 1774945 1775040 96 + 0.469 0.000 -11.389
ENSG00000197774 E006 5.014627 0.003162161 0.343203976 0.66457510 16 1775041 1775132 92 + 0.822 0.700 -0.492
ENSG00000197774 E007 2.387698 0.009180629 0.464564681 0.75736191 16 1775133 1775208 76 + 0.571 0.455 -0.557
ENSG00000197774 E008 3.519083 0.041612910 0.715467403 0.89452482 16 1775209 1775314 106 + 0.634 0.672 0.163
ENSG00000197774 E009 7.242319 0.023810184 0.925895740 0.97925855 16 1775315 1775408 94 + 0.913 0.908 -0.021
ENSG00000197774 E010 8.217479 0.001796354 0.109043025 0.38110857 16 1775569 1775684 116 + 1.022 0.855 -0.628
ENSG00000197774 E011 3.465426 0.117498115 0.409252372 0.71822137 16 1775797 1775811 15 + 0.689 0.577 -0.486
ENSG00000197774 E012 6.928640 0.119080978 0.290366129 0.61835665 16 1775812 1775918 107 + 0.943 0.816 -0.486
ENSG00000197774 E013 5.428629 0.003533276 0.993114404 1.00000000 16 1775919 1775986 68 + 0.809 0.795 -0.055
ENSG00000197774 E014 10.799494 0.001280356 0.014092609 0.11608865 16 1776068 1776339 272 + 0.980 1.163 0.665
ENSG00000197774 E015 7.816975 0.001969407 0.126734917 0.41252375 16 1776340 1776745 406 + 0.881 1.011 0.485
ENSG00000197774 E016 0.000000       16 1776746 1776860 115 +      
ENSG00000197774 E017 0.000000       16 1776861 1777405 545 +      
ENSG00000197774 E018 6.117532 0.002634593 0.134616627 0.42517005 16 1777406 1778454 1049 + 0.782 0.924 0.550
ENSG00000197774 E019 1.357818 0.012460660 0.265000631 0.59302856 16 1778455 1781708 3254 + 0.295 0.455 0.928

Help

Please Click HERE to learn more details about the results from DEXseq.