ENSG00000198252

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354586 ENSG00000198252 No_inf pgwt_inf STYX protein_coding protein_coding 11.29409 10.39919 10.64536 0.5004964 0.2732846 0.0337215 9.8673947 6.899077 10.01782 0.6034241 0.2058271 0.5374428 0.86660833 0.669725 0.942575 0.272850 0.3039289543 0.0002027873 FALSE TRUE
ENST00000556861 ENSG00000198252 No_inf pgwt_inf STYX protein_coding protein_coding_CDS_not_defined 11.29409 10.39919 10.64536 0.5004964 0.2732846 0.0337215 0.9611464 2.883439 0.00000 0.2742170 0.0000000 -8.1766415 0.09205833 0.276175 0.000000 -0.276175 0.0002027873 0.0002027873   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198252 E001 0.4555123 0.0532332592 0.0921620476   14 52730166 52730179 14 + 0.267 0.000 -11.049
ENSG00000198252 E002 1.8592959 0.0075865801 0.0090146008 0.08669368 14 52730180 52730210 31 + 0.599 0.195 -2.393
ENSG00000198252 E003 12.5638170 0.0011472074 0.0281190371 0.17762104 14 52730211 52730458 248 + 1.206 1.026 -0.648
ENSG00000198252 E004 8.5308512 0.0017234831 0.1954008770 0.51212298 14 52730459 52730531 73 + 1.032 0.907 -0.465
ENSG00000198252 E005 0.0000000       14 52731594 52731712 119 +      
ENSG00000198252 E006 8.0081881 0.0019361480 0.0556540993 0.26359872 14 52744852 52744884 33 + 1.032 0.841 -0.717
ENSG00000198252 E007 8.8126527 0.0219389296 0.5403394845 0.80523563 14 52746426 52746479 54 + 1.023 0.950 -0.270
ENSG00000198252 E008 8.3749807 0.0726771030 0.9672549752 0.99294716 14 52750683 52750780 98 + 0.977 0.964 -0.050
ENSG00000198252 E009 4.4797251 0.0035309164 0.7886250911 0.92678257 14 52756551 52756611 61 + 0.753 0.719 -0.138
ENSG00000198252 E010 5.6546789 0.0025145636 0.3604950099 0.67999993 14 52757319 52757355 37 + 0.867 0.764 -0.405
ENSG00000198252 E011 6.0959674 0.0022772915 0.0965567448 0.35787279 14 52757743 52757782 40 + 0.925 0.742 -0.715
ENSG00000198252 E012 7.7312102 0.0053117137 0.0144349127 0.11769187 14 52757874 52757924 51 + 1.040 0.784 -0.970
ENSG00000198252 E013 9.0599463 0.0044009920 0.4844221402 0.77092739 14 52759682 52759754 73 + 1.032 0.964 -0.251
ENSG00000198252 E014 9.1248027 0.0016049922 0.8259177423 0.94119776 14 52768840 52768933 94 + 0.996 1.014 0.066
ENSG00000198252 E015 110.8768318 0.0001668716 0.2444140196 0.57067922 14 52771033 52773615 2583 + 2.036 2.060 0.080
ENSG00000198252 E016 79.1820117 0.0002068024 0.0001079226 0.00314272 14 52773616 52774989 1374 + 1.849 1.958 0.370

Help

Please Click HERE to learn more details about the results from DEXseq.