ENSG00000198265

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358691 ENSG00000198265 No_inf pgwt_inf HELZ protein_coding protein_coding 6.187476 5.386118 6.092342 0.215225 0.5007984 0.1774412 4.2286206 5.202112 3.2686444 0.1308169 0.05766985 -0.6687686 0.7066833 0.96795 0.549925 -0.418025 0.043320326 0.009933971 FALSE TRUE
ENST00000579953 ENSG00000198265 No_inf pgwt_inf HELZ protein_coding nonsense_mediated_decay 6.187476 5.386118 6.092342 0.215225 0.5007984 0.1774412 0.1396335 0.000000 0.4189004 0.0000000 0.19517405 5.4225707 0.0207750 0.00000 0.062325 0.062325 0.816718668 0.009933971 TRUE TRUE
ENST00000580168 ENSG00000198265 No_inf pgwt_inf HELZ protein_coding protein_coding 6.187476 5.386118 6.092342 0.215225 0.5007984 0.1774412 1.1878256 0.000000 1.6361207 0.0000000 0.24353081 7.3629263 0.1821000 0.00000 0.271975 0.271975 0.009933971 0.009933971 FALSE TRUE
MSTRG.13173.9 ENSG00000198265 No_inf pgwt_inf HELZ protein_coding   6.187476 5.386118 6.092342 0.215225 0.5007984 0.1774412 0.1336874 0.000000 0.4010623 0.0000000 0.40106228 5.3612851 0.0186250 0.00000 0.055875 0.055875 0.992847247 0.009933971 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198265 E001 183.2412791 0.0001557114 8.893477e-16 2.026262e-13 17 67070444 67077928 7485 - 2.174 2.310 0.455
ENSG00000198265 E002 3.1620417 0.0123603545 8.856337e-02 3.415032e-01 17 67077929 67077971 43 - 0.463 0.696 1.059
ENSG00000198265 E003 26.0490129 0.0125609361 9.825062e-01 9.985369e-01 17 67077972 67078586 615 - 1.433 1.421 -0.043
ENSG00000198265 E004 15.0551447 0.0492396902 3.191764e-01 6.444056e-01 17 67086829 67087081 253 - 1.148 1.233 0.302
ENSG00000198265 E005 32.1030873 0.0220756767 1.979724e-01 5.155529e-01 17 67107169 67107685 517 - 1.573 1.465 -0.370
ENSG00000198265 E006 13.7452114 0.0010322663 3.033220e-01 6.302458e-01 17 67108492 67108726 235 - 1.210 1.125 -0.304
ENSG00000198265 E007 21.5707424 0.0136132350 1.900686e-01 5.046252e-01 17 67109116 67109686 571 - 1.406 1.300 -0.369
ENSG00000198265 E008 6.8024168 0.0026108503 7.533607e-02 3.122250e-01 17 67114324 67114403 80 - 0.987 0.799 -0.719
ENSG00000198265 E009 11.2381214 0.0016659915 1.205545e-01 4.018686e-01 17 67120405 67120612 208 - 1.156 1.020 -0.492
ENSG00000198265 E010 7.8856323 0.0018193915 3.229172e-02 1.922438e-01 17 67122970 67123160 191 - 1.054 0.842 -0.797
ENSG00000198265 E011 3.6470788 0.1375462715 2.974127e-01 6.250694e-01 17 67123963 67124014 52 - 0.750 0.587 -0.690
ENSG00000198265 E012 0.3423510 0.0156764413 7.079503e-02   17 67128495 67128650 156 - 0.259 0.000 -14.627
ENSG00000198265 E013 7.3110906 0.0022572803 1.296916e-01 4.179054e-01 17 67128651 67128855 205 - 0.999 0.842 -0.593
ENSG00000198265 E014 6.3310674 0.0233495383 5.869926e-01 8.306080e-01 17 67135970 67136198 229 - 0.827 0.881 0.211
ENSG00000198265 E015 7.7746455 0.0019935646 8.896683e-01 9.659806e-01 17 67137931 67138114 184 - 0.949 0.929 -0.074
ENSG00000198265 E016 5.6368726 0.0397371541 2.774832e-01 6.056191e-01 17 67145743 67145890 148 - 0.729 0.869 0.554
ENSG00000198265 E017 4.5679554 0.0032220778 9.226005e-01 9.780432e-01 17 67148569 67148714 146 - 0.750 0.733 -0.069
ENSG00000198265 E018 3.4368764 0.0041687388 6.109432e-01 8.430383e-01 17 67149867 67149985 119 - 0.682 0.611 -0.304
ENSG00000198265 E019 4.5152646 0.0101886219 2.980419e-01 6.256408e-01 17 67151046 67151224 179 - 0.809 0.676 -0.538
ENSG00000198265 E020 2.0756466 0.0314471586 5.414017e-01 8.057656e-01 17 67160261 67160362 102 - 0.538 0.441 -0.474
ENSG00000198265 E021 0.2287699 0.0154450336 1.825266e-01   17 67160363 67160365 3 - 0.189 0.000 -14.080
ENSG00000198265 E022 3.9741493 0.0265193123 5.334730e-02 2.577711e-01 17 67160897 67161076 180 - 0.827 0.562 -1.111
ENSG00000198265 E023 4.3820866 0.0247795621 2.585292e-01 5.862321e-01 17 67166478 67166608 131 - 0.809 0.656 -0.626
ENSG00000198265 E024 2.4529152 0.0398062337 6.914309e-01 8.824662e-01 17 67167463 67167525 63 - 0.571 0.506 -0.304
ENSG00000198265 E025 4.2512420 0.0207864289 1.879024e-01 5.023158e-01 17 67167526 67167711 186 - 0.809 0.634 -0.719
ENSG00000198265 E026 2.2082587 0.0077915249 6.835625e-01 8.789290e-01 17 67167712 67167796 85 - 0.538 0.475 -0.304
ENSG00000198265 E027 0.0000000       17 67176321 67176669 349 -      
ENSG00000198265 E028 4.4841778 0.0313728231 1.227505e-01 4.056734e-01 17 67178659 67178926 268 - 0.844 0.634 -0.856
ENSG00000198265 E029 0.1315150 0.0122755692 6.521930e-01   17 67179596 67179736 141 - 0.000 0.086 11.673
ENSG00000198265 E030 0.1139502 0.0111492650 4.420747e-01   17 67188218 67188318 101 - 0.104 0.000 -13.145
ENSG00000198265 E031 2.0450608 0.0121476947 1.133937e-01 3.894427e-01 17 67188319 67188387 69 - 0.601 0.366 -1.178
ENSG00000198265 E032 4.1519223 0.0127592205 3.875600e-01 7.019340e-01 17 67188388 67188616 229 - 0.771 0.656 -0.474
ENSG00000198265 E033 1.6046465 0.0137488394 9.423765e-01 9.854202e-01 17 67189589 67189622 34 - 0.420 0.405 -0.081
ENSG00000198265 E034 2.0610185 0.0070419024 2.643141e-01 5.923913e-01 17 67189623 67189696 74 - 0.571 0.405 -0.818
ENSG00000198265 E035 1.5871698 0.0200100025 5.417608e-01 8.060514e-01 17 67190157 67190188 32 - 0.463 0.366 -0.526
ENSG00000198265 E036 3.6928338 0.0038935957 4.002443e-03 4.969681e-02 17 67190189 67190355 167 - 0.844 0.475 -1.593
ENSG00000198265 E037 2.1223387 0.0234110509 6.808026e-03 7.196552e-02 17 67193967 67194042 76 - 0.682 0.274 -2.111
ENSG00000198265 E038 1.9633770 0.0793121525 7.361223e-01 9.041662e-01 17 67195419 67195470 52 - 0.502 0.441 -0.304
ENSG00000198265 E039 0.2628107 0.0160571622 3.165664e-01   17 67200613 67201128 516 - 0.000 0.159 12.622
ENSG00000198265 E040 1.9639405 0.0071634371 7.000964e-01 8.868311e-01 17 67201129 67201185 57 - 0.502 0.441 -0.304
ENSG00000198265 E041 2.0952940 0.0072885782 8.756479e-01 9.606647e-01 17 67203319 67203379 61 - 0.502 0.475 -0.134
ENSG00000198265 E042 2.4041682 0.0072322689 7.866579e-02 3.200040e-01 17 67203380 67203443 64 - 0.657 0.405 -1.197
ENSG00000198265 E043 0.1311489 0.0122099741 6.523577e-01   17 67215788 67215898 111 - 0.000 0.086 11.673
ENSG00000198265 E044 1.4223144 0.0386660595 4.645363e-02 2.372787e-01 17 67215899 67215935 37 - 0.538 0.220 -1.889
ENSG00000198265 E045 1.5195662 0.1235091855 1.274319e-02 1.086025e-01 17 67218595 67218607 13 - 0.601 0.159 -2.763
ENSG00000198265 E046 3.7794905 0.0038880451 2.854278e-01 6.132019e-01 17 67218608 67218822 215 - 0.750 0.611 -0.584
ENSG00000198265 E047 0.1145948 0.0111838080 4.421255e-01   17 67235380 67235399 20 - 0.104 0.000 -13.145
ENSG00000198265 E048 1.0154620 0.0178762887 2.455124e-01 5.719930e-01 17 67239433 67239489 57 - 0.189 0.366 1.281
ENSG00000198265 E049 0.1141751 0.0112356745 4.420100e-01   17 67239490 67239800 311 - 0.104 0.000 -13.145
ENSG00000198265 E050 0.4904200 0.0158379676 8.470911e-01   17 67243784 67243839 56 - 0.189 0.159 -0.304
ENSG00000198265 E051 0.0000000       17 67245148 67245196 49 -      
ENSG00000198265 E052 0.0000000       17 67245815 67245989 175 -      

Help

Please Click HERE to learn more details about the results from DEXseq.