ENSG00000198715

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000362007 ENSG00000198715 No_inf pgwt_inf GLMP protein_coding protein_coding 63.39899 71.4165 62.86534 1.57512 0.963763 -0.1839652 25.537062 28.109332 25.260615 2.9472347 2.8717782 -0.1541015 0.40335000 0.393100 0.402925 0.009825 1.000000e+00 5.879427e-05 FALSE  
ENST00000461597 ENSG00000198715 No_inf pgwt_inf GLMP protein_coding nonsense_mediated_decay 63.39899 71.4165 62.86534 1.57512 0.963763 -0.1839652 2.297093 5.011290 0.000000 0.2455129 0.0000000 -8.9719141 0.03418333 0.070275 0.000000 -0.070275 5.879427e-05 5.879427e-05    
ENST00000482579 ENSG00000198715 No_inf pgwt_inf GLMP protein_coding protein_coding_CDS_not_defined 63.39899 71.4165 62.86534 1.57512 0.963763 -0.1839652 3.236993 5.452891 1.193773 2.5829923 0.7208421 -2.1821013 0.04928333 0.074750 0.019050 -0.055700 9.928472e-01 5.879427e-05    
ENST00000622703 ENSG00000198715 No_inf pgwt_inf GLMP protein_coding protein_coding 63.39899 71.4165 62.86534 1.57512 0.963763 -0.1839652 17.866198 14.959093 22.076233 3.0167655 0.3740451 0.5611606 0.28608333 0.210100 0.351475 0.141375 9.716538e-01 5.879427e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198715 E001 0.1308632 0.0122296951 5.642031e-01   1 156290089 156290095 7 - 0.000 0.093 9.248
ENSG00000198715 E002 5.3772099 0.0026745914 6.882906e-05 0.002165892 1 156290096 156290360 265 - 0.477 0.961 2.023
ENSG00000198715 E003 0.8832881 0.0971207218 3.222755e-01 0.646939626 1 156290541 156290579 39 - 0.176 0.342 1.258
ENSG00000198715 E004 3.4344130 0.0044598126 8.998549e-01 0.970159765 1 156290580 156290686 107 - 0.654 0.639 -0.064
ENSG00000198715 E005 6.6159198 0.0053336650 1.141509e-01 0.390536621 1 156290687 156290976 290 - 0.779 0.949 0.658
ENSG00000198715 E006 4.9506106 0.0082515021 4.086770e-03 0.050418371 1 156290977 156291106 130 - 0.544 0.900 1.472
ENSG00000198715 E007 0.0000000       1 156291403 156291550 148 -      
ENSG00000198715 E008 0.3417064 0.0339342212 9.646091e-02   1 156292612 156292617 6 - 0.243 0.000 -13.651
ENSG00000198715 E009 0.6034327 0.2154580772 6.412969e-01   1 156292618 156292686 69 - 0.243 0.170 -0.649
ENSG00000198715 E010 0.4894825 0.0827743026 9.551351e-01   1 156292687 156292687 1 - 0.176 0.170 -0.064
ENSG00000198715 E011 0.2617264 0.2487309845 3.166337e-01   1 156292688 156292688 1 - 0.000 0.170 11.756
ENSG00000198715 E012 0.2617264 0.2487309845 3.166337e-01   1 156292689 156292694 6 - 0.000 0.170 11.756
ENSG00000198715 E013 0.0000000       1 156292695 156292885 191 -      
ENSG00000198715 E014 0.0000000       1 156292886 156293120 235 -      
ENSG00000198715 E015 7.1748807 0.0274160637 3.473023e-01 0.668102026 1 156293121 156293209 89 - 0.967 0.859 -0.408
ENSG00000198715 E016 1.3078402 0.0188729986 1.145679e-01 0.391108860 1 156293210 156293319 110 - 0.477 0.235 -1.479
ENSG00000198715 E017 25.1458868 0.0005725375 6.728743e-01 0.873483726 1 156293320 156293372 53 - 1.428 1.405 -0.078
ENSG00000198715 E018 26.8501033 0.0005417354 5.689940e-01 0.820607672 1 156293373 156293383 11 - 1.459 1.429 -0.104
ENSG00000198715 E019 37.5494744 0.0006696947 7.452295e-01 0.908618569 1 156293384 156293422 39 - 1.575 1.592 0.059
ENSG00000198715 E020 23.4646362 0.0111029086 5.069485e-01 0.784900025 1 156293423 156293429 7 - 1.358 1.409 0.180
ENSG00000198715 E021 48.6257497 0.0004995858 6.995540e-01 0.886519274 1 156293430 156293517 88 - 1.684 1.702 0.060
ENSG00000198715 E022 35.3152454 0.0009024206 5.956119e-01 0.835345240 1 156293518 156293576 59 - 1.572 1.547 -0.084
ENSG00000198715 E023 0.2617264 0.2487309845 3.166337e-01   1 156293577 156293616 40 - 0.000 0.170 11.756
ENSG00000198715 E024 0.0000000       1 156293617 156293617 1 -      
ENSG00000198715 E025 2.2791697 0.0281672189 8.516885e-02 0.334141849 1 156293618 156293710 93 - 0.352 0.614 1.315
ENSG00000198715 E026 4.1255973 0.0035254822 1.542529e-01 0.454647354 1 156293711 156293989 279 - 0.602 0.780 0.743
ENSG00000198715 E027 0.6228707 0.0144992015 6.951776e-01   1 156293990 156294017 28 - 0.176 0.235 0.521
ENSG00000198715 E028 82.2185818 0.0001983291 4.997747e-01 0.780407770 1 156294018 156294236 219 - 1.929 1.910 -0.064
ENSG00000198715 E029 65.9479887 0.0006817148 2.319975e-02 0.158206240 1 156294365 156294525 161 - 1.865 1.786 -0.267
ENSG00000198715 E030 27.8504030 0.0005292135 2.041431e-02 0.145990598 1 156294526 156294565 40 - 1.522 1.397 -0.431
ENSG00000198715 E031 1.5421775 0.0089752258 2.095380e-02 0.148313826 1 156294566 156294675 110 - 0.176 0.531 2.258
ENSG00000198715 E032 1.1637511 0.0114900917 1.689565e-02 0.130094929 1 156294676 156294758 83 - 0.097 0.465 2.936
ENSG00000198715 E033 53.4792437 0.0003565272 4.374105e-01 0.739102213 1 156294759 156295016 258 - 1.717 1.749 0.109
ENSG00000198715 E034 3.0917714 0.0049425452 6.367296e-01 0.855471864 1 156295017 156295283 267 - 0.574 0.639 0.284
ENSG00000198715 E035 1.5071967 0.0160283916 2.885384e-01 0.616020501 1 156295297 156295525 229 - 0.301 0.465 0.936
ENSG00000198715 E036 30.2471073 0.0055006729 9.052805e-01 0.972198622 1 156295526 156295689 164 - 1.488 1.497 0.030

Help

Please Click HERE to learn more details about the results from DEXseq.