ENSG00000198791

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000518541 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding protein_coding 122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 40.160002 28.972696 42.44862 4.9615011 6.6896431 0.5508658 0.32279167 0.310675 0.322250 0.011575 1.00000000 0.00362168    
ENST00000519918 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding protein_coding 122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 23.288363 12.943224 28.00157 3.1212505 0.8281894 1.1127118 0.18471667 0.135725 0.216875 0.081150 0.99284725 0.00362168 FALSE  
ENST00000519954 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding nonsense_mediated_decay 122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 2.122296 5.476825 0.00000 2.2266610 0.0000000 -9.0998276 0.02455833 0.067675 0.000000 -0.067675 0.00362168 0.00362168 FALSE  
ENST00000628418 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding protein_coding 122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 22.767011 9.845654 28.88528 6.0119119 1.0124263 1.5518102 0.17303333 0.091575 0.224900 0.133325 0.94511119 0.00362168    
MSTRG.27312.3 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding   122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 12.803959 8.432146 12.89289 0.9540559 0.9199063 0.6120126 0.10586667 0.097000 0.101150 0.004150 1.00000000 0.00362168 FALSE  
MSTRG.27312.5 ENSG00000198791 No_inf pgwt_inf CNOT7 protein_coding   122.4044 92.69485 129.6258 11.03371 6.507336 0.4837474 14.994655 16.871388 12.85817 1.1188460 1.0942075 -0.3916265 0.13130000 0.188675 0.099450 -0.089225 0.95009808 0.00362168 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198791 E001 1.8190740 2.179544e-02 9.180714e-04 1.683480e-02 8 17224966 17225039 74 - 0.097 0.616 3.649
ENSG00000198791 E002 19.2233599 7.131173e-04 7.417501e-11 8.969600e-09 8 17225040 17228008 2969 - 0.988 1.461 1.677
ENSG00000198791 E003 7.3232395 1.999738e-03 2.520899e-03 3.592603e-02 8 17228009 17228850 842 - 0.719 1.036 1.219
ENSG00000198791 E004 3.5035920 1.015362e-01 3.002107e-01 6.275430e-01 8 17228851 17229089 239 - 0.543 0.727 0.796
ENSG00000198791 E005 294.5446553 9.191216e-05 3.918466e-02 2.161686e-01 8 17229090 17230567 1478 - 2.451 2.484 0.109
ENSG00000198791 E006 101.8640712 1.525194e-04 8.855479e-03 8.572246e-02 8 17230568 17230848 281 - 2.049 1.976 -0.246
ENSG00000198791 E007 10.6868910 1.318083e-03 9.401733e-01 9.845549e-01 8 17230849 17231041 193 - 1.069 1.064 -0.018
ENSG00000198791 E008 28.1534636 4.838196e-04 8.159523e-05 2.499460e-03 8 17231042 17231569 528 - 1.326 1.552 0.779
ENSG00000198791 E009 37.3002430 1.735142e-03 5.237825e-03 5.997739e-02 8 17231570 17232328 759 - 1.497 1.642 0.493
ENSG00000198791 E010 8.2684588 1.717376e-03 2.144975e-02 1.505396e-01 8 17232329 17232426 98 - 0.828 1.055 0.851
ENSG00000198791 E011 69.4084633 2.460773e-04 4.612338e-01 7.550592e-01 8 17232427 17232537 111 - 1.859 1.835 -0.082
ENSG00000198791 E012 1.1129388 1.805484e-02 7.886074e-01 9.267826e-01 8 17234593 17234715 123 - 0.300 0.343 0.270
ENSG00000198791 E013 47.4661992 3.994071e-03 6.348583e-01 8.545111e-01 8 17234716 17234800 85 - 1.696 1.674 -0.074
ENSG00000198791 E014 42.4410073 4.236635e-03 8.281857e-01 9.421422e-01 8 17234801 17234860 60 - 1.630 1.642 0.040
ENSG00000198791 E015 38.3430007 4.014384e-04 9.929978e-01 1.000000e+00 8 17237212 17237241 30 - 1.593 1.594 0.004
ENSG00000198791 E016 67.9584354 1.118472e-03 2.485988e-01 5.755718e-01 8 17237242 17237373 132 - 1.859 1.818 -0.140
ENSG00000198791 E017 1.0153205 9.902319e-02 2.054964e-01 5.252026e-01 8 17237374 17237595 222 - 0.176 0.388 1.533
ENSG00000198791 E018 5.8810679 2.422717e-03 7.905360e-02 3.208194e-01 8 17241294 17242991 1698 - 0.719 0.915 0.768
ENSG00000198791 E019 20.7427626 6.716838e-04 1.843187e-01 4.976220e-01 8 17242992 17242993 2 - 1.379 1.296 -0.290
ENSG00000198791 E020 71.4199298 2.023443e-04 3.573085e-05 1.258665e-03 8 17242994 17243180 187 - 1.929 1.788 -0.477
ENSG00000198791 E021 22.5337750 6.351553e-04 5.734388e-03 6.373863e-02 8 17243181 17243185 5 - 1.454 1.285 -0.585
ENSG00000198791 E022 0.8836036 1.233577e-01 3.189341e-01 6.442273e-01 8 17243442 17243506 65 - 0.176 0.343 1.270
ENSG00000198791 E023 0.6213666 2.014772e-02 6.900042e-01   8 17243507 17243545 39 - 0.176 0.236 0.533
ENSG00000198791 E024 1.0607069 3.008176e-02 8.597372e-02 3.355636e-01 8 17243546 17243622 77 - 0.438 0.171 -1.859
ENSG00000198791 E025 0.1316618 1.237852e-02 5.597261e-01   8 17244327 17244541 215 - 0.000 0.094 8.746
ENSG00000198791 E026 0.7711616 3.294236e-02 1.074571e-01 3.785653e-01 8 17244740 17245035 296 - 0.097 0.343 2.271
ENSG00000198791 E027 46.6831649 2.940629e-04 1.757605e-04 4.623597e-03 8 17245036 17245247 212 - 1.756 1.596 -0.543
ENSG00000198791 E028 1.8497964 1.305293e-01 8.326948e-01 9.437529e-01 8 17245857 17245931 75 - 0.439 0.466 0.140
ENSG00000198791 E029 1.3409732 4.524968e-02 7.216498e-01 8.976744e-01 8 17246173 17246522 350 - 0.397 0.343 -0.315
ENSG00000198791 E030 1.4067506 3.153521e-01 1.526444e-01 4.520659e-01 8 17246523 17246534 12 - 0.176 0.500 2.118
ENSG00000198791 E031 1.2758874 2.454305e-01 1.546044e-01 4.552040e-01 8 17246535 17246674 140 - 0.176 0.466 1.948
ENSG00000198791 E032 13.7534826 1.704502e-03 1.576531e-01 4.596709e-01 8 17246675 17246878 204 - 1.223 1.115 -0.385
ENSG00000198791 E033 0.0000000       8 17247313 17247340 28 -      

Help

Please Click HERE to learn more details about the results from DEXseq.