ENSG00000198836

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361908 ENSG00000198836 No_inf pgwt_inf OPA1 protein_coding protein_coding 32.0196 22.96538 32.41053 2.034985 4.397657 0.496819 3.8156916 1.767026 3.648197 1.368518 1.3469083 1.0416681 0.12739167 0.087650 0.138650 0.051000 0.99284725 0.03583854 FALSE  
ENST00000392436 ENSG00000198836 No_inf pgwt_inf OPA1 protein_coding protein_coding 32.0196 22.96538 32.41053 2.034985 4.397657 0.496819 1.3647172 0.000000 2.399552 0.000000 0.5322978 7.9126213 0.04394167 0.000000 0.086800 0.086800 0.03583854 0.03583854 FALSE  
ENST00000482865 ENSG00000198836 No_inf pgwt_inf OPA1 protein_coding retained_intron 32.0196 22.96538 32.41053 2.034985 4.397657 0.496819 13.5729929 8.533641 12.430933 2.306586 4.1752801 0.5421718 0.38949167 0.355075 0.337825 -0.017250 1.00000000 0.03583854 FALSE  
ENST00000644959 ENSG00000198836 No_inf pgwt_inf OPA1 protein_coding nonsense_mediated_decay 32.0196 22.96538 32.41053 2.034985 4.397657 0.496819 0.7693796 1.628936 0.000000 1.155066 0.0000000 -7.3566157 0.02748333 0.066675 0.000000 -0.066675 0.94850618 0.03583854 TRUE  
ENST00000646544 ENSG00000198836 No_inf pgwt_inf OPA1 protein_coding protein_coding 32.0196 22.96538 32.41053 2.034985 4.397657 0.496819 2.5899520 3.397611 2.531159 0.634168 1.4641213 -0.4232741 0.09900833 0.148525 0.100025 -0.048500 0.99284725 0.03583854 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198836 E001 0.1138060 0.0112095789 7.615440e-01   3 193593144 193593185 42 + 0.082 0.000 -10.826
ENSG00000198836 E002 0.2276119 0.2878456149 4.566350e-01   3 193593186 193593207 22 + 0.150 0.000 -13.494
ENSG00000198836 E003 0.1138060 0.0112095789 7.615440e-01   3 193593208 193593215 8 + 0.082 0.000 -13.176
ENSG00000198836 E004 0.1138060 0.0112095789 7.615440e-01   3 193593216 193593216 1 + 0.082 0.000 -13.176
ENSG00000198836 E005 0.1138060 0.0112095789 7.615440e-01   3 193593217 193593217 1 + 0.082 0.000 -13.176
ENSG00000198836 E006 0.1138060 0.0112095789 7.615440e-01   3 193593218 193593219 2 + 0.082 0.000 -13.176
ENSG00000198836 E007 0.1138060 0.0112095789 7.615440e-01   3 193593220 193593221 2 + 0.082 0.000 -13.176
ENSG00000198836 E008 0.2449549 0.0164804020 7.884318e-01   3 193593222 193593227 6 + 0.082 0.111 0.486
ENSG00000198836 E009 1.3074110 0.2870732632 5.965134e-01 8.357485e-01 3 193593228 193593246 19 + 0.424 0.272 -0.929
ENSG00000198836 E010 1.9119484 0.3746076314 9.090677e-01 9.731552e-01 3 193593247 193593279 33 + 0.515 0.389 -0.652
ENSG00000198836 E011 1.7981424 0.5265878814 8.292022e-01 9.423766e-01 3 193593280 193593280 1 + 0.487 0.389 -0.515
ENSG00000198836 E012 1.9120926 0.3757388844 9.073824e-01 9.726260e-01 3 193593281 193593286 6 + 0.515 0.389 -0.652
ENSG00000198836 E013 1.9120926 0.3757388844 9.073824e-01 9.726260e-01 3 193593287 193593291 5 + 0.515 0.389 -0.652
ENSG00000198836 E014 2.3684745 0.1989353161 3.750332e-01 6.926319e-01 3 193593292 193593305 14 + 0.613 0.389 -1.099
ENSG00000198836 E015 5.9467650 0.0024020138 5.039138e-02 2.489601e-01 3 193593306 193593409 104 + 0.927 0.704 -0.877
ENSG00000198836 E016 0.0000000       3 193596800 193596946 147 +      
ENSG00000198836 E017 0.7984574 0.0126972002 1.491562e-02 1.201351e-01 3 193603500 193603557 58 + 0.389 0.000 -15.742
ENSG00000198836 E018 0.0000000       3 193614722 193614722 1 +      
ENSG00000198836 E019 5.8143718 0.0064190596 3.448761e-02 2.002197e-01 3 193614723 193614761 39 + 0.927 0.678 -0.983
ENSG00000198836 E020 22.2471167 0.0008353139 1.082456e-01 3.798976e-01 3 193614762 193615030 269 + 1.409 1.304 -0.364
ENSG00000198836 E021 4.1485176 0.0259787591 7.441646e-02 3.099184e-01 3 193615031 193615041 11 + 0.805 0.557 -1.044
ENSG00000198836 E022 7.1114375 0.0153953295 5.445025e-01 8.077986e-01 3 193615674 193615702 29 + 0.937 0.868 -0.264
ENSG00000198836 E023 10.9254753 0.0013489180 8.842923e-01 9.638063e-01 3 193615703 193615770 68 + 1.070 1.080 0.034
ENSG00000198836 E024 7.6731559 0.0018206007 6.340322e-01 8.541710e-01 3 193617178 193617285 108 + 0.916 0.960 0.164
ENSG00000198836 E025 0.3767001 0.0167329521 3.919110e-01   3 193617784 193617837 54 + 0.082 0.199 1.486
ENSG00000198836 E026 0.0000000       3 193618703 193618826 124 +      
ENSG00000198836 E027 0.0000000       3 193618827 193618868 42 +      
ENSG00000198836 E028 1.0614321 0.0553052949 2.534422e-01 5.803764e-01 3 193618869 193618936 68 + 0.389 0.199 -1.321
ENSG00000198836 E029 0.0000000       3 193618937 193618937 1 +      
ENSG00000198836 E030 0.2620121 0.0161484511 1.451269e-01   3 193626058 193626091 34 + 0.000 0.199 13.779
ENSG00000198836 E031 3.6271344 0.0064457536 8.748590e-01 9.604554e-01 3 193626092 193626202 111 + 0.674 0.651 -0.099
ENSG00000198836 E032 0.6042286 0.3646774482 9.114931e-01   3 193628509 193628616 108 + 0.210 0.199 -0.098
ENSG00000198836 E033 4.7556308 0.0029152168 6.913056e-02 2.978786e-01 3 193631612 193631665 54 + 0.845 0.622 -0.913
ENSG00000198836 E034 0.0000000       3 193631755 193631769 15 +      
ENSG00000198836 E035 8.3397599 0.0017672591 6.959196e-01 8.843548e-01 3 193635418 193635522 105 + 0.986 0.946 -0.151
ENSG00000198836 E036 4.7129024 0.0031519270 4.415437e-02 2.308101e-01 3 193637195 193637215 21 + 0.634 0.868 0.945
ENSG00000198836 E037 6.9692342 0.0184772530 4.245148e-01 7.293373e-01 3 193637216 193637281 66 + 0.858 0.946 0.334
ENSG00000198836 E038 8.9036657 0.0490861935 4.666150e-02 2.380885e-01 3 193637952 193638018 67 + 1.093 0.832 -0.974
ENSG00000198836 E039 8.2158234 0.0103129848 4.605984e-02 2.360167e-01 3 193638019 193638065 47 + 1.047 0.832 -0.807
ENSG00000198836 E040 8.5340438 0.0032356211 2.918914e-01 6.200371e-01 3 193642765 193642845 81 + 1.022 0.916 -0.394
ENSG00000198836 E041 11.2781357 0.0281262966 2.303232e-01 5.558102e-01 3 193642975 193643049 75 + 1.030 1.147 0.423
ENSG00000198836 E042 12.0219313 0.0140782431 1.351787e-01 4.260945e-01 3 193643373 193643444 72 + 1.047 1.182 0.486
ENSG00000198836 E043 11.5500094 0.0211413088 4.024896e-01 7.133571e-01 3 193643528 193643627 100 + 1.134 1.047 -0.315
ENSG00000198836 E044 0.1315150 0.0122967896 3.776621e-01   3 193643952 193643974 23 + 0.000 0.111 12.838
ENSG00000198836 E045 13.7302602 0.0140666055 4.001232e-01 7.117127e-01 3 193643975 193644105 131 + 1.201 1.120 -0.292
ENSG00000198836 E046 0.0000000       3 193644106 193644151 46 +      
ENSG00000198836 E047 9.8876672 0.0014157813 1.864999e-02 1.381984e-01 3 193645553 193645611 59 + 1.121 0.901 -0.812
ENSG00000198836 E048 6.2895914 0.0022476747 2.360110e-02 1.596849e-01 3 193645612 193645625 14 + 0.958 0.704 -0.992
ENSG00000198836 E049 12.4536756 0.0010637074 6.716669e-02 2.935867e-01 3 193645728 193645800 73 + 1.190 1.035 -0.556
ENSG00000198836 E050 0.1315150 0.0122967896 3.776621e-01   3 193646485 193646579 95 + 0.000 0.111 12.838
ENSG00000198836 E051 17.2641371 0.0008525325 4.661221e-01 7.580820e-01 3 193647065 193647180 116 + 1.283 1.229 -0.192
ENSG00000198836 E052 14.8426841 0.0011342541 4.661613e-01 7.581008e-01 3 193648070 193648134 65 + 1.223 1.165 -0.207
ENSG00000198836 E053 1.6025645 0.1910306172 5.257178e-01 7.960368e-01 3 193648135 193648460 326 + 0.351 0.481 0.707
ENSG00000198836 E054 0.8338708 0.0132731831 4.842990e-01 7.708300e-01 3 193648766 193648794 29 + 0.308 0.199 -0.836
ENSG00000198836 E055 16.4776177 0.0052796783 2.079449e-01 5.285520e-01 3 193648795 193648871 77 + 1.283 1.182 -0.359
ENSG00000198836 E056 28.5073456 0.0065844554 9.300925e-01 9.804503e-01 3 193654862 193655027 166 + 1.467 1.468 0.003
ENSG00000198836 E057 0.2631768 0.0161220960 1.452087e-01   3 193655028 193655052 25 + 0.000 0.199 13.779
ENSG00000198836 E058 31.9706714 0.0004839198 7.580401e-01 9.140500e-01 3 193657080 193657232 153 + 1.525 1.505 -0.067
ENSG00000198836 E059 24.0187297 0.0006277899 2.894292e-01 6.172558e-01 3 193658887 193658995 109 + 1.368 1.428 0.207
ENSG00000198836 E060 16.6998638 0.0009485887 7.040069e-01 8.890710e-01 3 193659482 193659561 80 + 1.259 1.229 -0.108
ENSG00000198836 E061 18.0341025 0.0075213039 1.656416e-01 4.714879e-01 3 193662822 193662890 69 + 1.324 1.214 -0.386
ENSG00000198836 E062 23.5830858 0.0149205999 6.731917e-01 8.736149e-01 3 193662891 193662962 72 + 1.405 1.368 -0.130
ENSG00000198836 E063 25.9762525 0.0037132412 8.615660e-01 9.554638e-01 3 193664880 193664996 117 + 1.426 1.433 0.024
ENSG00000198836 E064 23.3221372 0.0006363180 7.242533e-01 8.988593e-01 3 193666296 193666389 94 + 1.376 1.394 0.062
ENSG00000198836 E065 13.0607698 0.0011710462 7.300883e-01 9.016090e-01 3 193667170 193667175 6 + 1.160 1.129 -0.110
ENSG00000198836 E066 26.9104185 0.0005336640 3.069972e-01 6.334246e-01 3 193667176 193667280 105 + 1.471 1.409 -0.213
ENSG00000198836 E067 0.1308632 0.0122449285 3.776879e-01   3 193667371 193667455 85 + 0.000 0.111 12.838
ENSG00000198836 E068 0.0000000       3 193668315 193668333 19 +      
ENSG00000198836 E069 0.7373364 0.1855225575 7.775075e-01 9.227114e-01 3 193668334 193668484 151 + 0.210 0.272 0.487
ENSG00000198836 E070 0.3433647 0.0259075236 1.909842e-01   3 193668485 193668931 447 + 0.210 0.000 -14.602
ENSG00000198836 E071 0.0000000       3 193689069 193689170 102 +      
ENSG00000198836 E072 0.0000000       3 193691394 193692062 669 +      
ENSG00000198836 E073 17.9656169 0.0014542246 3.417626e-01 6.635025e-01 3 193692063 193692132 70 + 1.306 1.236 -0.246
ENSG00000198836 E074 218.7107807 0.0001063543 1.763043e-12 2.643867e-10 3 193694606 193697811 3206 + 2.282 2.401 0.399

Help

Please Click HERE to learn more details about the results from DEXseq.