ENSG00000198945

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361794 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding protein_coding 10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 1.0321082 0.9616297 1.3327731 0.3751436 0.5584068 0.4667371 0.10944167 0.137150 0.106250 -0.030900 0.9980558422 0.0004096536 FALSE TRUE
ENST00000368136 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding protein_coding 10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 0.5066797 1.5200392 0.0000000 1.5200392 0.0000000 -7.2574248 0.08333333 0.250000 0.000000 -0.250000 0.9928472467 0.0004096536 FALSE TRUE
ENST00000526019 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding protein_coding 10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 0.7965275 0.0000000 0.4784241 0.0000000 0.4784241 5.6100625 0.07254167 0.000000 0.034150 0.034150 1.0000000000 0.0004096536 FALSE TRUE
ENST00000531313 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding retained_intron 10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 1.8378639 0.0000000 5.5135916 0.0000000 1.4293863 9.1094629 0.12871667 0.000000 0.386150 0.386150 0.0004096536 0.0004096536   FALSE
ENST00000533560 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding protein_coding 10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 4.2843280 2.0770460 4.5538045 1.1993962 1.6161187 1.1287746 0.44255833 0.354175 0.369075 0.014900 0.9928472467 0.0004096536 FALSE TRUE
MSTRG.25300.10 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding   10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 0.9491500 1.5734020 1.2740481 1.1920926 1.2740481 -0.3023284 0.08359167 0.178200 0.072575 -0.105625 0.9928472467 0.0004096536 FALSE TRUE
MSTRG.25300.5 ENSG00000198945 No_inf pgwt_inf L3MBTL3 protein_coding   10.34327 6.926446 13.71098 0.9908816 1.398768 0.9841147 0.6026936 0.3509084 0.0000000 0.3509084 0.0000000 -5.1735607 0.05424167 0.035550 0.000000 -0.035550 0.9928472467 0.0004096536 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000198945 E001 0.0000000       6 130013699 130013720 22 +      
ENSG00000198945 E002 0.0000000       6 130016226 130016292 67 +      
ENSG00000198945 E003 0.2633236 0.1891123805 0.194802548   6 130018369 130018580 212 + 0.000 0.195 11.533
ENSG00000198945 E004 0.0000000       6 130018581 130018582 2 +      
ENSG00000198945 E005 0.0000000       6 130018583 130018588 6 +      
ENSG00000198945 E006 0.8680478 0.0152338780 0.455206057 0.75147520 6 130018589 130018664 76 + 0.213 0.329 0.837
ENSG00000198945 E007 0.2625250 0.0161184538 0.159537744   6 130019208 130019237 30 + 0.000 0.195 14.018
ENSG00000198945 E008 0.1316618 0.0122610365 0.402691736   6 130019367 130019463 97 + 0.000 0.108 13.098
ENSG00000198945 E009 0.0000000       6 130020491 130020519 29 +      
ENSG00000198945 E010 0.1138060 0.0111849673 0.714721742   6 130020520 130020556 37 + 0.083 0.000 -13.343
ENSG00000198945 E011 0.5872522 0.0151837265 0.290634235   6 130020557 130020668 112 + 0.266 0.108 -1.578
ENSG00000198945 E012 3.1109285 0.0970316321 0.168731062 0.47561499 6 130022227 130022305 79 + 0.494 0.720 1.006
ENSG00000198945 E013 0.1138060 0.0111849673 0.714721742   6 130025075 130025101 27 + 0.083 0.000 -13.343
ENSG00000198945 E014 4.3487030 0.0686840790 0.634254747 0.85424451 6 130042685 130042765 81 + 0.752 0.696 -0.231
ENSG00000198945 E015 4.1211489 0.0034148872 0.833999935 0.94445966 6 130042766 130042801 36 + 0.719 0.696 -0.093
ENSG00000198945 E016 6.8013114 0.0100177901 0.986577870 0.99968565 6 130049282 130049393 112 + 0.890 0.892 0.007
ENSG00000198945 E017 0.0000000       6 130049651 130049755 105 +      
ENSG00000198945 E018 1.6191179 0.0441355793 0.210595823 0.53170788 6 130049756 130049830 75 + 0.313 0.514 1.100
ENSG00000198945 E019 6.4599540 0.0023673695 0.733003574 0.90277307 6 130051249 130051408 160 + 0.853 0.892 0.149
ENSG00000198945 E020 7.5288402 0.0021080322 0.079475600 0.32196594 6 130052859 130052991 133 + 0.840 1.015 0.659
ENSG00000198945 E021 0.0000000       6 130055087 130055170 84 +      
ENSG00000198945 E022 6.7217960 0.0223385961 0.558635132 0.81543322 6 130055171 130055255 85 + 0.853 0.923 0.264
ENSG00000198945 E023 9.1688734 0.0016941455 0.393616638 0.70682674 6 130057406 130057497 92 + 1.039 0.965 -0.275
ENSG00000198945 E024 12.0178867 0.0013215029 0.099386616 0.36346362 6 130060036 130060140 105 + 1.169 1.038 -0.471
ENSG00000198945 E025 11.1178676 0.0013317831 0.450874172 0.74829010 6 130066353 130066488 136 + 1.109 1.049 -0.216
ENSG00000198945 E026 7.4261399 0.0028291192 0.837849006 0.94603961 6 130068330 130068421 92 + 0.913 0.937 0.089
ENSG00000198945 E027 0.0000000       6 130070847 130070975 129 +      
ENSG00000198945 E028 9.8857325 0.0440007196 0.709944611 0.89226691 6 130070976 130071127 152 + 1.013 1.060 0.172
ENSG00000198945 E029 4.8964741 0.0719969251 0.616353627 0.84574545 6 130078558 130078634 77 + 0.736 0.805 0.277
ENSG00000198945 E030 5.4808619 0.0071433029 0.844973598 0.94879684 6 130083620 130083705 86 + 0.799 0.824 0.100
ENSG00000198945 E031 6.0944598 0.0023897124 0.089143152 0.34264712 6 130086140 130086250 111 + 0.924 0.743 -0.708
ENSG00000198945 E032 7.5582060 0.0048943397 0.001335589 0.02238746 6 130092745 130092859 115 + 1.056 0.720 -1.286
ENSG00000198945 E033 9.8090044 0.0019207539 0.685833150 0.88027414 6 130094265 130094367 103 + 1.047 1.015 -0.119
ENSG00000198945 E034 13.7726774 0.0010860592 0.632740332 0.85346071 6 130104426 130104575 150 + 1.150 1.189 0.140
ENSG00000198945 E035 3.8940476 0.0037319995 0.927444029 0.97975097 6 130120879 130120958 80 + 0.682 0.696 0.059
ENSG00000198945 E036 0.0000000       6 130133452 130133621 170 +      
ENSG00000198945 E037 6.5893074 0.0050314707 0.626305365 0.85039892 6 130133843 130133905 63 + 0.853 0.908 0.208
ENSG00000198945 E038 58.5941132 0.0002978384 0.366376351 0.68517773 6 130139610 130141449 1840 + 1.758 1.792 0.115

Help

Please Click HERE to learn more details about the results from DEXseq.