ENSG00000204220

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374606 ENSG00000204220 No_inf pgwt_inf PFDN6 protein_coding protein_coding 71.18901 59.97849 82.52938 2.816681 5.067234 0.4603969 7.413999 0.2636128 8.334541 0.2636128 1.396402 4.9306253 0.09978333 0.004125 0.101100 0.096975 0.03418934 0.03418934 FALSE TRUE
ENST00000374607 ENSG00000204220 No_inf pgwt_inf PFDN6 protein_coding protein_coding 71.18901 59.97849 82.52938 2.816681 5.067234 0.4603969 48.230591 43.3097114 56.628553 2.4994527 3.562928 0.3867608 0.67784167 0.724525 0.686000 -0.038525 0.99284725 0.03418934 FALSE TRUE
ENST00000395131 ENSG00000204220 No_inf pgwt_inf PFDN6 protein_coding protein_coding 71.18901 59.97849 82.52938 2.816681 5.067234 0.4603969 3.994817 4.0691639 5.606302 1.6724953 1.646328 0.4613471 0.05671667 0.068450 0.067975 -0.000475 1.00000000 0.03418934 FALSE TRUE
ENST00000395134 ENSG00000204220 No_inf pgwt_inf PFDN6 protein_coding retained_intron 71.18901 59.97849 82.52938 2.816681 5.067234 0.4603969 4.624631 5.2779050 4.615329 1.6886665 1.802569 -0.1931403 0.06716667 0.086925 0.058875 -0.028050 0.99284725 0.03418934   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000204220 E001 1.3931856 0.0096909459 5.287698e-02 0.256419768 6 33289302 33289595 294 + 0.217 0.509 1.784
ENSG00000204220 E002 0.7534556 0.0142262705 2.593732e-01 0.587035786 6 33289596 33289596 1 + 0.156 0.325 1.369
ENSG00000204220 E003 1.2099311 0.0483124031 8.467798e-01 0.949431953 6 33289597 33289600 4 + 0.360 0.325 -0.216
ENSG00000204220 E004 7.8848065 0.0454359568 8.466124e-01 0.949348006 6 33289601 33289620 20 + 0.963 0.930 -0.123
ENSG00000204220 E005 3.2868276 0.0047090945 9.304973e-01 0.980628600 6 33289621 33289624 4 + 0.626 0.637 0.047
ENSG00000204220 E006 3.3035157 0.0044443384 6.388238e-01 0.856730953 6 33289625 33289626 2 + 0.604 0.664 0.262
ENSG00000204220 E007 3.7778044 0.0036996874 8.654614e-01 0.957264013 6 33289627 33289628 2 + 0.669 0.690 0.089
ENSG00000204220 E008 1.8772928 0.0076651307 3.726929e-02 0.209839402 6 33289629 33289769 141 + 0.580 0.264 -1.746
ENSG00000204220 E009 18.9985816 0.0009192782 1.702918e-01 0.477933291 6 33289770 33289774 5 + 1.256 1.345 0.313
ENSG00000204220 E010 60.1879018 0.0002680522 1.334069e-01 0.423186531 6 33289775 33289920 146 + 1.810 1.757 -0.177
ENSG00000204220 E011 52.5811042 0.0002868751 2.261170e-01 0.550646238 6 33290174 33290244 71 + 1.749 1.704 -0.155
ENSG00000204220 E012 1.9638332 0.0408049845 6.158547e-01 0.845540746 6 33290245 33290325 81 + 0.435 0.509 0.369
ENSG00000204220 E013 65.8304099 0.0002256758 6.581648e-01 0.866615503 6 33290326 33290450 125 + 1.831 1.817 -0.049
ENSG00000204220 E014 13.2062483 0.0054104860 3.694323e-02 0.208932452 6 33290451 33290715 265 + 1.063 1.234 0.612
ENSG00000204220 E015 43.8063519 0.0053391561 5.454991e-01 0.808350901 6 33290716 33290934 219 + 1.663 1.636 -0.090
ENSG00000204220 E016 6.9466078 0.0022414572 4.666697e-05 0.001576934 6 33296829 33298401 1573 + 0.648 1.074 1.655

Help

Please Click HERE to learn more details about the results from DEXseq.