ENSG00000227345

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000402038 ENSG00000227345 No_inf pgwt_inf PARG protein_coding protein_coding 9.890937 21.18176 3.96524 11.26147 0.401308 -2.414389 1.852891 3.3310076 0.000000 0.06350685 0.0000000 -8.384139 0.28431667 0.352950 0.000000 -0.352950 0.224848850 0.006758706 FALSE TRUE
ENST00000616448 ENSG00000227345 No_inf pgwt_inf PARG protein_coding protein_coding 9.890937 21.18176 3.96524 11.26147 0.401308 -2.414389 1.876549 0.1578281 3.447655 0.15782809 0.1303242 4.364738 0.45380000 0.013175 0.899675 0.886500 0.006758706 0.006758706 FALSE TRUE
MSTRG.3405.11 ENSG00000227345 No_inf pgwt_inf PARG protein_coding   9.890937 21.18176 3.96524 11.26147 0.401308 -2.414389 1.434215 4.3026451 0.000000 2.70212217 0.0000000 -8.752429 0.10606667 0.318200 0.000000 -0.318200 0.992847247 0.006758706   FALSE
MSTRG.3405.9 ENSG00000227345 No_inf pgwt_inf PARG protein_coding   9.890937 21.18176 3.96524 11.26147 0.401308 -2.414389 4.090400 12.2712010 0.000000 12.27120099 0.0000000 -10.262236 0.07535833 0.226075 0.000000 -0.226075 1.000000000 0.006758706   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000227345 E001 15.8292598 0.001280846 0.538391024 0.80401181 10 49818279 49818991 713 - 1.206 1.233 0.098
ENSG00000227345 E002 5.9625410 0.005577385 0.452941083 0.74996082 10 49818992 49819144 153 - 0.798 0.867 0.267
ENSG00000227345 E003 9.7429806 0.001636016 0.066593507 0.29201907 10 49819145 49819494 350 - 0.937 1.084 0.538
ENSG00000227345 E004 2.6038898 0.139910711 0.798992688 0.93090897 10 49820165 49820209 45 - 0.528 0.571 0.197
ENSG00000227345 E005 3.9790488 0.004279231 0.464048912 0.75698161 10 49820210 49820293 84 - 0.647 0.725 0.329
ENSG00000227345 E006 2.8835060 0.005385556 0.235227584 0.56034794 10 49832803 49832908 106 - 0.493 0.644 0.688
ENSG00000227345 E007 0.6395832 0.019006877 0.216905494   10 49832909 49833300 392 - 0.102 0.281 1.781
ENSG00000227345 E008 3.2422992 0.004581417 0.376945627 0.69444857 10 49841950 49842058 109 - 0.561 0.666 0.459
ENSG00000227345 E009 2.8803341 0.008176926 0.238835567 0.56457504 10 49843554 49843632 79 - 0.493 0.644 0.688
ENSG00000227345 E010 0.0000000       10 49857295 49857305 11 -      
ENSG00000227345 E011 2.0928498 0.007507920 0.998981557 1.00000000 10 49857306 49857453 148 - 0.493 0.483 -0.049
ENSG00000227345 E012 1.3247532 0.011974587 0.273054007 0.60132955 10 49861588 49861650 63 - 0.455 0.281 -1.026
ENSG00000227345 E013 0.5881373 0.019088287 0.135993367   10 49861651 49861663 13 - 0.313 0.089 -2.219
ENSG00000227345 E014 0.3600120 0.018990127 0.512925810   10 49865321 49865381 61 - 0.184 0.089 -1.219
ENSG00000227345 E015 0.0000000       10 49867072 49867434 363 -      
ENSG00000227345 E016 0.0000000       10 49869476 49869555 80 -      
ENSG00000227345 E017 1.0330250 0.012934528 0.038321493 0.21326670 10 49879673 49879830 158 - 0.102 0.413 2.588
ENSG00000227345 E018 1.4880373 0.009723869 0.711248845 0.89272413 10 49885203 49885295 93 - 0.366 0.413 0.267
ENSG00000227345 E019 0.0000000       10 49908455 49908462 8 -      
ENSG00000227345 E020 0.1315150 0.012260922 0.603342747   10 49908463 49908541 79 - 0.000 0.089 9.838
ENSG00000227345 E021 0.2461098 0.016458082 0.925875454   10 49913126 49913150 25 - 0.102 0.089 -0.219
ENSG00000227345 E022 2.2074321 0.008665994 0.801897785 0.93214513 10 49915917 49915991 75 - 0.529 0.483 -0.219
ENSG00000227345 E023 1.2103308 0.015602693 0.416898572 0.72382142 10 49922336 49922419 84 - 0.412 0.281 -0.804
ENSG00000227345 E024 1.8153283 0.477364841 0.602633398 0.83867654 10 49922547 49922669 123 - 0.529 0.373 -0.804
ENSG00000227345 E025 4.6898542 0.004622347 0.030384965 0.18606717 10 49932100 49932283 184 - 0.881 0.621 -1.055
ENSG00000227345 E026 9.3598981 0.018765842 0.971328357 0.99459015 10 49933177 49933820 644 - 1.022 1.003 -0.067
ENSG00000227345 E027 1.6037744 0.012195869 0.951780787 0.98799988 10 49933821 49934046 226 - 0.412 0.413 0.003
ENSG00000227345 E028 2.6828042 0.204284616 0.692837115 0.88318265 10 49934047 49934163 117 - 0.620 0.515 -0.481
ENSG00000227345 E029 1.9456002 0.303331674 0.562157976 0.81711839 10 49935076 49935142 67 - 0.528 0.413 -0.581
ENSG00000227345 E030 2.1227638 0.007969828 0.007767871 0.07862063 10 49941509 49941785 277 - 0.672 0.281 -2.026
ENSG00000227345 E031 0.9303951 0.012134198 0.016876242 0.12999927 10 49941786 49941824 39 - 0.455 0.089 -3.026
ENSG00000227345 E032 0.6846514 0.013999184 0.006171082 0.06726860 10 49941825 49941934 110 - 0.412 0.000 -13.282
ENSG00000227345 E033 0.3767609 0.017128646 0.659600084   10 49941935 49942027 93 - 0.102 0.163 0.781
ENSG00000227345 E034 0.0000000       10 49970167 49970203 37 -      

Help

Please Click HERE to learn more details about the results from DEXseq.