ENSG00000004487

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356634 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding protein_coding 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 5.1626589 0.000000 11.9477696 0.000000 0.5177660 10.2237326 0.16150000 0.000000 0.368100 0.368100 4.814613e-18 4.814613e-18 FALSE TRUE
ENST00000494920 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding protein_coding 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 9.6194973 8.532773 9.7740930 2.183769 1.4739145 0.1957336 0.29569167 0.261875 0.292375 0.030500 8.797735e-01 4.814613e-18 FALSE TRUE
ENST00000685243 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding protein_coding 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 0.8412779 2.523834 0.0000000 1.515126 0.0000000 -7.9851780 0.02550833 0.076525 0.000000 -0.076525 4.864700e-01 4.814613e-18 FALSE TRUE
ENST00000690907 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding retained_intron 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 2.2265586 3.926676 1.5836656 0.442571 0.1189521 -1.3046291 0.06993333 0.123725 0.048325 -0.075400 2.930411e-01 4.814613e-18   FALSE
ENST00000691404 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding protein_coding 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 1.2531358 2.907665 0.8517421 1.348513 0.8517421 -1.7594864 0.03782500 0.087800 0.025675 -0.062125 4.661415e-01 4.814613e-18 FALSE TRUE
ENST00000692975 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding protein_coding 32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 1.1586516 0.000000 2.2307618 0.000000 0.7696554 7.8078455 0.03665833 0.000000 0.067700 0.067700 3.595230e-02 4.814613e-18 FALSE TRUE
MSTRG.422.27 ENSG00000004487 No_inf pgKDN_inf KDM1A protein_coding   32.20988 32.25886 32.90834 1.327899 1.562983 0.02874895 7.3473192 5.739403 4.6248495 2.121944 0.5591664 -0.3108896 0.23070000 0.184325 0.139075 -0.045250 1.000000e+00 4.814613e-18 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000004487 E001 0.0000000       1 23019443 23019447 5 +      
ENSG00000004487 E002 0.0000000       1 23019448 23019467 20 +      
ENSG00000004487 E003 0.0000000       1 23019468 23019475 8 +      
ENSG00000004487 E004 0.0000000       1 23019476 23019480 5 +      
ENSG00000004487 E005 13.6838139 0.0275858820 4.051653e-03 4.280760e-02 1 23019481 23019947 467 + 1.299 1.006 -1.051
ENSG00000004487 E006 10.6669319 0.0012975205 1.310088e-03 1.844864e-02 1 23030469 23030634 166 + 1.192 0.917 -1.005
ENSG00000004487 E007 3.9539680 0.0035645894 2.525510e-01 5.441034e-01 1 23044427 23044486 60 + 0.609 0.755 0.611
ENSG00000004487 E008 7.1506254 0.0019704615 3.415188e-01 6.330471e-01 1 23050387 23050424 38 + 0.854 0.953 0.376
ENSG00000004487 E009 11.3505183 0.0011954724 1.669716e-01 4.374096e-01 1 23050425 23050520 96 + 1.147 1.035 -0.406
ENSG00000004487 E010 11.6920207 0.0251646190 1.491739e-01 4.114276e-01 1 23053761 23053839 79 + 1.178 1.026 -0.550
ENSG00000004487 E011 0.0000000       1 23053840 23055068 1229 +      
ENSG00000004487 E012 12.8939396 0.0094061102 4.312366e-02 2.024222e-01 1 23055069 23055161 93 + 1.227 1.053 -0.621
ENSG00000004487 E013 0.0000000       1 23055162 23055418 257 +      
ENSG00000004487 E014 16.2042694 0.0009557846 2.858566e-02 1.583707e-01 1 23055932 23056038 107 + 1.310 1.157 -0.541
ENSG00000004487 E015 2.2214799 0.0066756557 4.608278e-01 7.319790e-01 1 23056039 23057483 1445 + 0.446 0.554 0.526
ENSG00000004487 E016 20.3945339 0.0006834301 1.427463e-01 4.021284e-01 1 23057484 23057565 82 + 1.376 1.285 -0.316
ENSG00000004487 E017 24.5807132 0.0164675162 4.397182e-01 7.156450e-01 1 23059073 23059167 95 + 1.437 1.379 -0.198
ENSG00000004487 E018 1.2600039 0.0098202884 1.099762e-02 8.559219e-02 1 23065199 23066059 861 + 0.099 0.493 3.044
ENSG00000004487 E019 0.0000000       1 23066060 23066071 12 +      
ENSG00000004487 E020 0.2542726 0.2543217859 3.359275e-01   1 23068170 23068538 369 + 0.000 0.167 11.138
ENSG00000004487 E021 30.6113692 0.0054577872 4.411286e-01 7.166849e-01 1 23068539 23068681 143 + 1.521 1.478 -0.149
ENSG00000004487 E022 0.3802764 0.0265955763 1.242514e-01   1 23068682 23069060 379 + 0.000 0.231 12.116
ENSG00000004487 E023 23.3786360 0.0040336089 3.793360e-03 4.093459e-02 1 23069061 23069151 91 + 1.476 1.290 -0.643
ENSG00000004487 E024 2.8588416 0.0050877470 9.670290e-02 3.238519e-01 1 23069152 23070853 1702 + 0.446 0.677 1.066
ENSG00000004487 E025 0.3618970 0.0166384190 5.269243e-01   1 23070854 23071224 371 + 0.179 0.091 -1.126
ENSG00000004487 E026 24.2198708 0.0005814660 1.529575e-03 2.079034e-02 1 23071225 23071356 132 + 1.490 1.306 -0.639
ENSG00000004487 E027 8.8799530 0.0017762352 5.582366e-02 2.354134e-01 1 23071357 23071359 3 + 1.079 0.905 -0.646
ENSG00000004487 E028 0.1268540 0.0123650882 5.905401e-01   1 23071360 23072123 764 + 0.000 0.091 10.621
ENSG00000004487 E029 17.1980595 0.0008457102 6.815497e-02 2.634277e-01 1 23072124 23072197 74 + 1.321 1.198 -0.434
ENSG00000004487 E030 0.3809057 0.0158363765 1.224405e-01   1 23073274 23073291 18 + 0.000 0.231 12.143
ENSG00000004487 E031 22.7617805 0.0027945437 4.436189e-01 7.184165e-01 1 23073292 23073403 112 + 1.399 1.353 -0.157
ENSG00000004487 E032 1.6336397 0.0639824586 2.440901e-02 1.432820e-01 1 23074463 23075666 1204 + 0.179 0.554 2.333
ENSG00000004487 E033 1.8674929 0.0125463185 1.028584e-01 3.352961e-01 1 23075667 23076782 1116 + 0.306 0.554 1.333
ENSG00000004487 E034 0.9878868 0.0116948456 5.678998e-01 8.055837e-01 1 23076783 23077227 445 + 0.247 0.337 0.611
ENSG00000004487 E035 9.5272501 0.0025179069 2.798674e-01 5.731241e-01 1 23077228 23077233 6 + 1.070 0.975 -0.349
ENSG00000004487 E036 22.6836892 0.0015542405 8.976866e-01 9.662566e-01 1 23077234 23077360 127 + 1.376 1.371 -0.017
ENSG00000004487 E037 18.2460319 0.0030417149 5.111337e-10 4.617669e-08 1 23077361 23078965 1605 + 0.963 1.443 1.707
ENSG00000004487 E038 2.5941431 0.1138554768 4.704452e-01 7.381211e-01 1 23078966 23078989 24 + 0.484 0.607 0.574
ENSG00000004487 E039 12.4949036 0.0095725654 7.872394e-01 9.183494e-01 1 23078990 23079012 23 + 1.139 1.120 -0.069
ENSG00000004487 E040 35.3396161 0.0004691596 1.775507e-01 4.522076e-01 1 23079013 23079177 165 + 1.592 1.529 -0.216
ENSG00000004487 E041 5.4899015 0.0256643719 5.983225e-03 5.637653e-02 1 23079363 23079552 190 + 0.581 0.941 1.459
ENSG00000004487 E042 35.1773125 0.0028128683 6.436188e-01 8.489762e-01 1 23079553 23079667 115 + 1.569 1.547 -0.076
ENSG00000004487 E043 21.5737327 0.0142237415 1.106931e-06 5.089616e-05 1 23079668 23080872 1205 + 1.088 1.495 1.426
ENSG00000004487 E044 8.7376002 0.0033645091 7.936912e-05 1.959128e-03 1 23080873 23081445 573 + 0.728 1.128 1.514
ENSG00000004487 E045 34.7609763 0.0004321561 4.817069e-01 7.467129e-01 1 23081446 23081573 128 + 1.531 1.569 0.129
ENSG00000004487 E046 7.2034747 0.0019745929 1.074693e-02 8.422336e-02 1 23081574 23082219 646 + 0.748 1.016 1.026
ENSG00000004487 E047 23.9080395 0.0006387284 9.814063e-02 3.267356e-01 1 23082220 23082292 73 + 1.337 1.439 0.354
ENSG00000004487 E048 22.3309483 0.0213091020 1.675602e-01 4.382093e-01 1 23082293 23082355 63 + 1.300 1.416 0.405
ENSG00000004487 E049 12.3354318 0.0273351832 2.942941e-01 5.876076e-01 1 23082356 23082366 11 + 1.060 1.171 0.398
ENSG00000004487 E050 2.9453764 0.0047118296 8.611343e-01 9.518539e-01 1 23082367 23082449 83 + 0.581 0.607 0.115
ENSG00000004487 E051 4.6765660 0.0030164691 4.979468e-01 7.584923e-01 1 23082450 23082509 60 + 0.707 0.789 0.333
ENSG00000004487 E052 17.8348271 0.0008182754 1.724007e-03 2.276196e-02 1 23082510 23083178 669 + 1.139 1.362 0.785
ENSG00000004487 E053 76.0001958 0.0053139908 5.341311e-01 7.843346e-01 1 23083179 23083692 514 + 1.898 1.874 -0.080

Help

Please Click HERE to learn more details about the results from DEXseq.