ENSG00000004897

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000066544 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding protein_coding 26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 8.197791 6.906548 11.259080 1.414636 1.690859 0.7042458 0.3313250 0.415025 0.353825 -0.061200 0.875556203 0.007716997 FALSE TRUE
ENST00000531206 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding protein_coding 26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 1.709172 0.000000 1.767259 0.000000 1.020381 7.4735103 0.0598250 0.000000 0.053025 0.053025 0.571284922 0.007716997 FALSE TRUE
ENST00000533415 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding nonsense_mediated_decay 26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 1.444254 0.000000 2.244900 0.000000 1.320227 7.8169199 0.0450750 0.000000 0.077900 0.077900 0.611169967 0.007716997 FALSE TRUE
ENST00000570740 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding nonsense_mediated_decay 26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 2.813625 0.657250 3.723620 0.384627 2.256106 2.4842757 0.0854500 0.035225 0.110550 0.075325 0.971319736 0.007716997   FALSE
MSTRG.12819.3 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding   26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 6.386331 0.719007 8.399927 0.719007 3.139302 3.5280888 0.2226000 0.037800 0.285525 0.247725 0.274916870 0.007716997 FALSE TRUE
MSTRG.12819.5 ENSG00000004897 No_inf pgKDN_inf CDC27 protein_coding   26.15196 16.78634 31.32776 1.120095 1.602362 0.8997555 2.062726 5.868382 0.000000 2.418200 0.000000 -9.1992754 0.1228083 0.360425 0.000000 -0.360425 0.007716997 0.007716997 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000004897 E001 0.0000000       17 47117703 47117713 11 -      
ENSG00000004897 E002 0.2356421 0.0156526003 3.910869e-01   17 47117714 47117756 43 - 0.149 0.000 -9.986
ENSG00000004897 E003 0.3543453 0.0157600052 1.926085e-01   17 47117757 47117757 1 - 0.208 0.000 -12.943
ENSG00000004897 E004 0.4713493 0.0158247337 9.849620e-02   17 47117758 47117759 2 - 0.260 0.000 -13.325
ENSG00000004897 E005 232.3985393 0.0001066183 8.535713e-05 0.002086877 17 47117760 47120254 2495 - 2.335 2.399 0.214
ENSG00000004897 E006 38.6021198 0.0003813783 2.516218e-01 0.542817190 17 47120255 47120609 355 - 1.617 1.561 -0.190
ENSG00000004897 E007 25.0701141 0.0039444450 9.682885e-01 0.993641226 17 47120610 47120770 161 - 1.411 1.413 0.004
ENSG00000004897 E008 13.1861727 0.0014229130 1.254565e-01 0.375485239 17 47120771 47120809 39 - 1.197 1.073 -0.447
ENSG00000004897 E009 15.4927104 0.0009023864 1.161643e-01 0.359305142 17 47120810 47120879 70 - 1.260 1.142 -0.419
ENSG00000004897 E010 23.6506933 0.0008487680 2.277834e-01 0.516209609 17 47120880 47121017 138 - 1.418 1.344 -0.259
ENSG00000004897 E011 19.5777302 0.0008483388 9.671712e-01 0.993372659 17 47122444 47122536 93 - 1.311 1.308 -0.012
ENSG00000004897 E012 9.7454388 0.0015976864 6.405470e-01 0.847427221 17 47122537 47122551 15 - 1.009 1.051 0.151
ENSG00000004897 E013 13.7448687 0.0010119674 9.229552e-01 0.976329510 17 47122552 47122600 49 - 1.168 1.160 -0.029
ENSG00000004897 E014 0.3724075 0.0164851979 3.860353e-01   17 47122601 47122619 19 - 0.081 0.200 1.514
ENSG00000004897 E015 14.9954531 0.0050685036 5.686640e-01 0.806014032 17 47123886 47123960 75 - 1.180 1.225 0.160
ENSG00000004897 E016 18.6686339 0.0516457800 3.905364e-01 0.676120780 17 47129393 47129521 129 - 1.319 1.247 -0.254
ENSG00000004897 E017 18.3751839 0.0007400828 2.331962e-02 0.139491088 17 47132257 47132374 118 - 1.344 1.186 -0.558
ENSG00000004897 E018 28.0553284 0.0009735398 4.000479e-01 0.683625336 17 47137152 47137360 209 - 1.438 1.485 0.160
ENSG00000004897 E019 19.7959020 0.0007890225 4.160660e-01 0.696001282 17 47138739 47138891 153 - 1.336 1.282 -0.190
ENSG00000004897 E020 1.1055784 0.0112746481 3.909356e-01 0.676200097 17 47139771 47139973 203 - 0.260 0.391 0.836
ENSG00000004897 E021 0.0000000       17 47141844 47141852 9 -      
ENSG00000004897 E022 18.4225108 0.0007603351 1.548414e-01 0.420398400 17 47141853 47142022 170 - 1.324 1.225 -0.346
ENSG00000004897 E023 2.8025948 0.0050603356 8.235158e-01 0.935925533 17 47142023 47142025 3 - 0.564 0.594 0.135
ENSG00000004897 E024 16.2944494 0.0008670096 8.402974e-01 0.942666949 17 47142229 47142427 199 - 1.240 1.225 -0.053
ENSG00000004897 E025 7.0907765 0.0188572242 4.565514e-01 0.728855131 17 47142428 47142436 9 - 0.866 0.949 0.314
ENSG00000004897 E026 17.0030442 0.0008159504 5.331739e-01 0.783718549 17 47143883 47143982 100 - 1.270 1.225 -0.158
ENSG00000004897 E027 9.9587178 0.0029675264 7.009916e-01 0.878197465 17 47151806 47151813 8 - 1.051 1.015 -0.130
ENSG00000004897 E028 17.4706702 0.0008147762 3.707508e-01 0.658988499 17 47151814 47151918 105 - 1.289 1.225 -0.223
ENSG00000004897 E029 0.6083965 0.0174087163 9.587262e-01 0.990197733 17 47151919 47151936 18 - 0.208 0.200 -0.071
ENSG00000004897 E030 8.3750006 0.0021104282 5.594138e-01 0.800501329 17 47154672 47154697 26 - 0.992 0.935 -0.212
ENSG00000004897 E031 7.4000462 0.0019139124 5.847032e-01 0.815396040 17 47154698 47154754 57 - 0.944 0.888 -0.211
ENSG00000004897 E032 5.0052635 0.0028821815 5.063658e-01 0.765129802 17 47154755 47154786 32 - 0.741 0.817 0.302
ENSG00000004897 E033 0.8626054 0.2073300056 4.956645e-01 0.756756669 17 47154787 47154864 78 - 0.208 0.336 0.929
ENSG00000004897 E034 0.6244813 0.0149273445 7.993276e-02 0.290192061 17 47156647 47156912 266 - 0.081 0.336 2.514
ENSG00000004897 E035 7.2056367 0.0019084231 4.775000e-01 0.743828596 17 47156913 47156983 71 - 0.878 0.949 0.268
ENSG00000004897 E036 9.3890629 0.0015929135 5.964408e-01 0.822617066 17 47156984 47157054 71 - 0.992 1.039 0.175
ENSG00000004897 E037 6.1173211 0.0100543276 3.535518e-01 0.643240592 17 47157055 47157059 5 - 0.801 0.904 0.398
ENSG00000004897 E038 10.4673228 0.0016835329 8.951913e-01 0.965339027 17 47157060 47157124 65 - 1.051 1.062 0.040
ENSG00000004897 E039 17.6734123 0.0008481029 1.236113e-01 0.372283446 17 47157230 47157384 155 - 1.311 1.202 -0.384
ENSG00000004897 E040 7.0328682 0.0037484755 4.491324e-01 0.722981800 17 47158206 47158303 98 - 0.933 0.854 -0.304
ENSG00000004897 E041 0.0000000       17 47169917 47170042 126 -      
ENSG00000004897 E042 8.0093911 0.0115850104 6.193612e-01 0.835365561 17 47171917 47172064 148 - 0.973 0.920 -0.200
ENSG00000004897 E043 0.4972190 0.0279963075 1.798919e-01   17 47181282 47181561 280 - 0.081 0.274 2.099
ENSG00000004897 E044 6.4455576 0.0201868468 8.465517e-01 0.945586580 17 47181562 47181637 76 - 0.878 0.854 -0.095
ENSG00000004897 E045 0.6335114 0.0221006057 7.231845e-03 0.064469803 17 47188746 47188936 191 - 0.000 0.391 13.399
ENSG00000004897 E046 6.5421029 0.0022064656 3.733893e-01 0.661098435 17 47189146 47189260 115 - 0.912 0.817 -0.368
ENSG00000004897 E047 2.0766001 0.0250057207 6.391937e-01 0.846520038 17 47189261 47189422 162 - 0.454 0.524 0.344

Help

Please Click HERE to learn more details about the results from DEXseq.