ENSG00000005007

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262803 ENSG00000005007 No_inf pgKDN_inf UPF1 protein_coding protein_coding 32.11502 33.3105 30.64629 0.8775588 0.5203524 -0.1202267 12.899458 7.142250 16.909926 0.6566157 0.7332041 1.2422542 0.40629167 0.214425 0.55205 0.337625 3.708207e-05 3.708207e-05 FALSE TRUE
ENST00000596842 ENSG00000005007 No_inf pgKDN_inf UPF1 protein_coding retained_intron 32.11502 33.3105 30.64629 0.8775588 0.5203524 -0.1202267 2.561756 3.971641 1.982336 0.9788704 0.3740515 -0.9989019 0.07909167 0.119175 0.06450 -0.054675 7.510617e-01 3.708207e-05 FALSE TRUE
ENST00000704679 ENSG00000005007 No_inf pgKDN_inf UPF1 protein_coding protein_coding_CDS_not_defined 32.11502 33.3105 30.64629 0.8775588 0.5203524 -0.1202267 12.720645 16.274760 9.015405 2.5065541 1.4183812 -0.8514588 0.39550833 0.494350 0.29480 -0.199550 4.227550e-01 3.708207e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000005007 E001 0.6083329 1.474773e-02 5.547861e-01 7.975327e-01 19 18831959 18831975 17 + 0.252 0.163 -0.783
ENSG00000005007 E002 1.0979653 1.093284e-02 5.990972e-01 8.242152e-01 19 18831976 18832000 25 + 0.364 0.282 -0.520
ENSG00000005007 E003 23.1182182 8.680755e-03 3.707409e-03 4.029734e-02 19 18832001 18832440 440 + 1.482 1.275 -0.720
ENSG00000005007 E004 0.1272623 1.231732e-02 6.127956e-01   19 18833130 18833283 154 + 0.000 0.089 11.668
ENSG00000005007 E005 14.3564672 1.280564e-02 2.735735e-02 1.539696e-01 19 18845980 18846119 140 + 1.281 1.086 -0.691
ENSG00000005007 E006 0.0000000       19 18847442 18847743 302 +      
ENSG00000005007 E007 14.0844123 5.362762e-03 1.824278e-03 2.376584e-02 19 18847744 18847833 90 + 1.298 1.044 -0.908
ENSG00000005007 E008 0.1170040 1.168443e-02 4.715883e-01   19 18848081 18848434 354 + 0.101 0.000 -12.800
ENSG00000005007 E009 0.0000000       19 18849008 18849031 24 +      
ENSG00000005007 E010 0.1170040 1.168443e-02 4.715883e-01   19 18849032 18849076 45 + 0.101 0.000 -12.800
ENSG00000005007 E011 0.0000000       19 18849082 18849165 84 +      
ENSG00000005007 E012 0.0000000       19 18849166 18849181 16 +      
ENSG00000005007 E013 0.0000000       19 18849182 18849216 35 +      
ENSG00000005007 E014 0.1268540 1.229400e-02 6.128728e-01   19 18849217 18849446 230 + 0.000 0.089 11.668
ENSG00000005007 E015 0.0000000       19 18849813 18849985 173 +      
ENSG00000005007 E016 21.4529262 1.106821e-03 1.229480e-05 4.080663e-04 19 18850075 18850242 168 + 1.482 1.200 -0.983
ENSG00000005007 E017 18.2286220 8.254947e-04 1.175468e-03 1.693767e-02 19 18850688 18850868 181 + 1.391 1.168 -0.783
ENSG00000005007 E018 0.1272623 1.231732e-02 6.127956e-01   19 18851050 18851129 80 + 0.000 0.089 11.668
ENSG00000005007 E019 21.8941334 1.612354e-03 1.372027e-03 1.913105e-02 19 18852135 18852296 162 + 1.459 1.253 -0.716
ENSG00000005007 E020 7.0541316 2.076339e-03 7.229734e-02 2.727726e-01 19 18852987 18852997 11 + 0.996 0.812 -0.701
ENSG00000005007 E021 14.0515726 2.467995e-02 3.325920e-01 6.247351e-01 19 18852998 18853071 74 + 1.223 1.132 -0.324
ENSG00000005007 E022 1.8386608 7.688312e-03 9.973460e-01 1.000000e+00 19 18853072 18853104 33 + 0.453 0.452 -0.005
ENSG00000005007 E023 20.7467160 6.918359e-04 9.928133e-01 1.000000e+00 19 18853252 18853350 99 + 1.337 1.334 -0.010
ENSG00000005007 E024 0.2340080 2.414054e-01 2.495820e-01   19 18854594 18854600 7 + 0.183 0.000 -12.938
ENSG00000005007 E025 17.2617822 1.777688e-02 4.980552e-01 7.586023e-01 19 18854601 18854709 109 + 1.292 1.230 -0.218
ENSG00000005007 E026 11.8571295 1.176718e-03 2.508686e-01 5.419727e-01 19 18854879 18854912 34 + 1.157 1.061 -0.347
ENSG00000005007 E027 24.7683208 6.445850e-04 1.237764e-01 3.725538e-01 19 18854913 18855038 126 + 1.357 1.447 0.310
ENSG00000005007 E028 0.7428026 1.385517e-02 5.099957e-01 7.675766e-01 19 18855039 18855123 85 + 0.183 0.282 0.802
ENSG00000005007 E029 11.1375506 1.895611e-03 3.492514e-02 1.787369e-01 19 18855124 18855138 15 + 0.973 1.154 0.660
ENSG00000005007 E030 21.4472298 6.951616e-04 1.588856e-01 4.259960e-01 19 18855139 18855242 104 + 1.298 1.386 0.304
ENSG00000005007 E031 0.8539812 1.487113e-02 5.852407e-01 8.157536e-01 19 18855243 18855680 438 + 0.311 0.227 -0.613
ENSG00000005007 E032 23.4504752 5.453889e-03 8.145236e-02 2.933982e-01 19 18855925 18856089 165 + 1.447 1.329 -0.409
ENSG00000005007 E033 15.9783211 9.897240e-04 7.636894e-01 9.078471e-01 19 18856186 18856300 115 + 1.217 1.236 0.069
ENSG00000005007 E034 22.0626765 6.038759e-04 1.493400e-01 4.115741e-01 19 18856877 18857020 144 + 1.310 1.398 0.307
ENSG00000005007 E035 36.2184806 3.868857e-04 9.803791e-01 9.978172e-01 19 18857320 18857533 214 + 1.570 1.567 -0.012
ENSG00000005007 E036 6.1705779 4.853396e-02 4.574225e-01 7.292744e-01 19 18859383 18860320 938 + 0.795 0.895 0.387
ENSG00000005007 E037 28.6895595 5.107058e-04 5.378939e-01 7.868259e-01 19 18860321 18860438 118 + 1.490 1.454 -0.124
ENSG00000005007 E038 31.2463394 1.789078e-03 4.060777e-01 6.887664e-01 19 18860826 18860982 157 + 1.532 1.484 -0.164
ENSG00000005007 E039 8.5618896 3.493993e-03 3.156935e-01 6.085381e-01 19 18862010 18862012 3 + 1.029 0.932 -0.363
ENSG00000005007 E040 31.1004419 1.023130e-03 5.199754e-01 7.745775e-01 19 18862013 18862152 140 + 1.486 1.518 0.111
ENSG00000005007 E041 0.6266801 1.507796e-02 2.225050e-01 5.098988e-01 19 18862933 18863437 505 + 0.101 0.282 1.802
ENSG00000005007 E042 41.9552283 3.490091e-04 8.057293e-01 9.281010e-01 19 18863438 18863612 175 + 1.638 1.625 -0.046
ENSG00000005007 E043 25.2529849 1.449092e-02 7.219996e-01 8.881968e-01 19 18864170 18864251 82 + 1.431 1.406 -0.086
ENSG00000005007 E044 34.6886112 9.517120e-03 5.171312e-01 7.726668e-01 19 18865289 18865450 162 + 1.529 1.567 0.130
ENSG00000005007 E045 0.0000000       19 18865451 18865560 110 +      
ENSG00000005007 E046 44.9363918 3.351690e-04 9.116843e-01 9.717930e-01 19 18865561 18865778 218 + 1.664 1.656 -0.024
ENSG00000005007 E047 25.1779652 5.965745e-04 4.433124e-02 2.058527e-01 19 18866044 18866166 123 + 1.347 1.464 0.405
ENSG00000005007 E048 361.2119628 8.069048e-05 1.342419e-07 7.630078e-06 19 18866521 18868230 1710 + 2.519 2.585 0.222

Help

Please Click HERE to learn more details about the results from DEXseq.