ENSG00000005238

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000378566 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding protein_coding 27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 2.2421915 4.477998 1.0641366 1.8089654 1.0641366 -2.0628947 0.08165000 0.157950 0.040025 -0.117925 0.345297708 0.005040859 FALSE TRUE
ENST00000488109 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding protein_coding 27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 0.5201756 1.560527 0.0000000 1.5605269 0.0000000 -7.2951048 0.01886667 0.056600 0.000000 -0.056600 0.850302318 0.005040859 FALSE TRUE
MSTRG.28663.1 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding   27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 5.8814207 1.088894 10.9568554 1.0888941 1.6508004 3.3190256 0.21279167 0.040100 0.389600 0.349500 0.005040859 0.005040859 FALSE TRUE
MSTRG.28663.12 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding   27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 2.3732955 5.500754 0.8644949 0.4048852 0.5006583 -2.6557280 0.08752500 0.203300 0.030825 -0.172475 0.047697999 0.005040859 FALSE TRUE
MSTRG.28663.14 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding   27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 9.5206113 9.376887 11.0182430 0.9715658 1.6526159 0.2324843 0.34742500 0.344850 0.391400 0.046550 0.861926654 0.005040859 FALSE TRUE
MSTRG.28663.4 ENSG00000005238 No_inf pgKDN_inf FAM214B protein_coding   27.22364 27.14961 27.85227 1.121428 0.9418541 0.03684988 2.6234257 2.167606 2.9110882 1.5175198 2.4832323 0.4237631 0.10088333 0.086725 0.110075 0.023350 1.000000000 0.005040859 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000005238 E001 0.1265070 0.0122340972 6.064837e-01   9 35104099 35104111 13 - 0.000 0.090 9.500
ENSG00000005238 E002 0.1265070 0.0122340972 6.064837e-01   9 35104112 35104116 5 - 0.000 0.090 11.466
ENSG00000005238 E003 0.2452102 0.0162170496 9.247698e-01   9 35104117 35104119 3 - 0.100 0.090 -0.169
ENSG00000005238 E004 0.3638483 0.0167922548 5.109073e-01   9 35104120 35104120 1 - 0.182 0.090 -1.169
ENSG00000005238 E005 0.3638483 0.0167922548 5.109073e-01   9 35104121 35104122 2 - 0.182 0.090 -1.169
ENSG00000005238 E006 0.3638483 0.0167922548 5.109073e-01   9 35104123 35104127 5 - 0.182 0.090 -1.169
ENSG00000005238 E007 0.8538900 0.0137812454 5.945507e-01 0.8217091306 9 35104128 35104141 14 - 0.309 0.229 -0.584
ENSG00000005238 E008 0.8538900 0.0137812454 5.945507e-01 0.8217091306 9 35104142 35104161 20 - 0.309 0.229 -0.584
ENSG00000005238 E009 187.2587431 0.0001213367 8.184942e-01 0.9339397475 9 35104162 35105374 1213 - 2.274 2.272 -0.006
ENSG00000005238 E010 9.1094515 0.0016084151 3.061359e-05 0.0008787192 9 35105375 35105681 307 - 0.733 1.144 1.551
ENSG00000005238 E011 29.4512465 0.0005556744 8.634650e-01 0.9527895762 9 35105682 35105857 176 - 1.485 1.478 -0.024
ENSG00000005238 E012 3.7636187 0.0786790443 5.225355e-03 0.0512414669 9 35105858 35105940 83 - 0.361 0.831 2.154
ENSG00000005238 E013 16.5396850 0.0024291062 5.405957e-01 0.7886116365 9 35105941 35106009 69 - 1.265 1.223 -0.147
ENSG00000005238 E014 25.5320244 0.0005981248 9.637554e-01 0.9923478745 9 35106252 35106410 159 - 1.422 1.422 -0.002
ENSG00000005238 E015 13.0761977 0.0011861082 1.908261e-01 0.4701342265 9 35106538 35106643 106 - 1.198 1.098 -0.358
ENSG00000005238 E016 7.9034803 0.0017976084 3.592819e-02 0.1818415706 9 35106833 35106891 59 - 1.046 0.845 -0.754
ENSG00000005238 E017 0.0000000       9 35106892 35106928 37 -      
ENSG00000005238 E018 15.6561598 0.0010663860 3.851643e-01 0.6712169243 9 35107381 35107568 188 - 1.252 1.192 -0.214
ENSG00000005238 E019 8.2812719 0.0018538158 8.816081e-02 0.3079367253 9 35107569 35107682 114 - 1.046 0.886 -0.596
ENSG00000005238 E020 32.3512908 0.0005003532 5.261907e-01 0.7786252231 9 35107683 35108127 445 - 1.538 1.507 -0.103
ENSG00000005238 E021 13.2524889 0.0014985182 9.727224e-03 0.0788876851 9 35108128 35108234 107 - 1.025 1.235 0.751
ENSG00000005238 E022 11.8090355 0.0012463698 5.273529e-01 0.7794105292 9 35108235 35108344 110 - 1.076 1.129 0.194
ENSG00000005238 E023 5.2677871 0.0035718511 8.094184e-01 0.9297038175 9 35108345 35108349 5 - 0.810 0.784 -0.102
ENSG00000005238 E024 0.1271363 0.0122315147 6.066962e-01   9 35108350 35108593 244 - 0.000 0.090 11.466
ENSG00000005238 E025 15.0347375 0.0009733835 2.578633e-01 0.5500682465 9 35108594 35108737 144 - 1.246 1.165 -0.286
ENSG00000005238 E026 3.6257799 0.0039733879 3.495301e-03 0.0387413785 9 35108738 35111268 2531 - 0.408 0.800 1.770
ENSG00000005238 E027 0.1187032 0.0117569597 4.766317e-01   9 35111269 35111588 320 - 0.100 0.000 -12.468
ENSG00000005238 E028 0.4884040 0.0161282445 9.045660e-01   9 35112330 35112392 63 - 0.182 0.165 -0.169
ENSG00000005238 E029 8.3491803 0.1715571776 9.461098e-01 0.9855241586 9 35115671 35115792 122 - 0.969 0.969 0.000
ENSG00000005238 E030 1.5886056 0.0167988922 6.234908e-01 0.8378578744 9 35115793 35115804 12 - 0.450 0.378 -0.391
ENSG00000005238 E031 2.0968659 0.0215397662 6.543223e-01 0.8548744870 9 35115805 35115895 91 - 0.450 0.520 0.346
ENSG00000005238 E032 0.0000000       9 35116262 35116341 80 -      

Help

Please Click HERE to learn more details about the results from DEXseq.