ENSG00000005436

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000321027 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 1.2144092 1.5829637 0.6749709 0.6043781 0.6749709 -1.2175987 0.17735000 0.307400 0.043100 -0.264300 0.4529374 0.0455808 FALSE TRUE
ENST00000409857 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 0.7285637 0.4061994 0.8344909 0.4061994 0.8344909 1.0208072 0.07365833 0.053375 0.053300 -0.000075 1.0000000 0.0455808 FALSE TRUE
ENST00000427862 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 0.8628408 0.4826859 0.0000000 0.4826859 0.0000000 -5.6225963 0.09718333 0.036175 0.000000 -0.036175 0.8074895 0.0455808 FALSE TRUE
ENST00000470197 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding retained_intron 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 1.2464720 1.1439524 1.6144055 0.5168818 0.9353354 0.4933280 0.16785000 0.164375 0.190825 0.026450 0.9446645 0.0455808 FALSE TRUE
ENST00000470503 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 0.4957111 0.8680406 0.2016643 0.1930440 0.2016643 -2.0525098 0.07507500 0.155200 0.021150 -0.134050 0.2907509 0.0455808 FALSE TRUE
ENST00000492826 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 0.1963240 0.5889719 0.0000000 0.5889719 0.0000000 -5.9044164 0.02580000 0.077400 0.000000 -0.077400 0.8342481 0.0455808   FALSE
ENST00000541687 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding protein_coding 8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 0.2122779 0.0000000 0.6368336 0.0000000 0.6368336 6.0153227 0.03124167 0.000000 0.093725 0.093725 0.8923031 0.0455808 FALSE TRUE
MSTRG.16556.10 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding   8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 1.1387122 2.2217753 1.1943613 2.2217753 1.1943613 -0.8899235 0.08094167 0.166550 0.076275 -0.090275 0.9975710 0.0455808   FALSE
MSTRG.16556.5 ENSG00000005436 No_inf pgKDN_inf GCFC2 protein_coding   8.315985 7.496845 9.873249 2.093503 2.013439 0.3967786 1.6787791 0.0000000 3.2930922 0.0000000 1.0988877 8.3676734 0.22450000 0.000000 0.421975 0.421975 0.0455808 0.0455808 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000005436 E001 0.0000000       2 75652000 75652187 188 -      
ENSG00000005436 E002 0.2458395 0.0162725952 0.788360106   2 75662705 75662705 1 - 0.081 0.111 0.507
ENSG00000005436 E003 0.2458395 0.0162725952 0.788360106   2 75662706 75662707 2 - 0.081 0.111 0.507
ENSG00000005436 E004 23.9769187 0.0007349033 0.027472538 0.15440849 2 75662708 75664417 1710 - 1.337 1.458 0.419
ENSG00000005436 E005 0.7274444 0.0143310811 0.684138099 0.86923552 2 75664418 75664418 1 - 0.260 0.200 -0.493
ENSG00000005436 E006 3.5411213 0.0045269304 0.715790891 0.88542027 2 75664419 75664561 143 - 0.632 0.681 0.208
ENSG00000005436 E007 2.1895118 0.0088022918 0.825197908 0.93667734 2 75664562 75664633 72 - 0.513 0.483 -0.145
ENSG00000005436 E008 1.4790298 0.0107105796 0.244585899 0.53489756 2 75664634 75664644 11 - 0.307 0.483 0.993
ENSG00000005436 E009 5.7363582 0.0076105825 0.663741950 0.86015275 2 75664645 75664783 139 - 0.802 0.853 0.199
ENSG00000005436 E010 3.4257579 0.0048546916 0.363967949 0.65265529 2 75665929 75666053 125 - 0.588 0.706 0.507
ENSG00000005436 E011 0.0000000       2 75670138 75670284 147 -      
ENSG00000005436 E012 1.9577697 0.0080037358 0.495046142 0.75634737 2 75671950 75672016 67 - 0.422 0.523 0.507
ENSG00000005436 E013 4.2753988 0.0040034264 0.394977881 0.67977334 2 75673444 75673520 77 - 0.672 0.775 0.425
ENSG00000005436 E014 1.3391197 0.1361787602 0.792939046 0.92099439 2 75674451 75674550 100 - 0.348 0.391 0.246
ENSG00000005436 E015 6.7210729 0.0022630483 0.376390523 0.66353685 2 75680193 75680314 122 - 0.842 0.934 0.350
ENSG00000005436 E016 7.7649377 0.0022331019 0.355620197 0.64540076 2 75687827 75687977 151 - 0.974 0.887 -0.327
ENSG00000005436 E017 8.4888554 0.0018379347 0.447687517 0.72184091 2 75689026 75689225 200 - 1.001 0.934 -0.252
ENSG00000005436 E018 3.0295799 0.0054765354 0.574977904 0.80964543 2 75689969 75690081 113 - 0.632 0.559 -0.323
ENSG00000005436 E019 0.2530140 0.2121815278 0.182202246   2 75690488 75690637 150 - 0.000 0.200 10.794
ENSG00000005436 E020 0.0000000       2 75690638 75690719 82 -      
ENSG00000005436 E021 3.7371176 0.0137245680 0.164186053 0.43340106 2 75691977 75692100 124 - 0.742 0.559 -0.782
ENSG00000005436 E022 6.6257102 0.0025491155 0.053402058 0.22999174 2 75694241 75694427 187 - 0.955 0.754 -0.778
ENSG00000005436 E023 0.0000000       2 75694428 75694479 52 -      
ENSG00000005436 E024 2.0597574 0.0134273154 0.607204153 0.82902637 2 75696200 75696251 52 - 0.513 0.439 -0.367
ENSG00000005436 E025 3.1402848 0.0086252252 0.266328933 0.55976714 2 75696252 75696315 64 - 0.672 0.523 -0.663
ENSG00000005436 E026 3.0039902 0.0077325065 0.069511806 0.26653276 2 75701190 75701287 98 - 0.690 0.439 -1.156
ENSG00000005436 E027 0.1271363 0.0124211125 0.377820716   2 75701288 75701372 85 - 0.000 0.111 10.160
ENSG00000005436 E028 1.6245803 0.0103706139 0.009881345 0.07964611 2 75701796 75702198 403 - 0.208 0.593 2.244
ENSG00000005436 E029 2.8969035 0.0052214764 0.211788833 0.49682686 2 75702199 75702312 114 - 0.652 0.483 -0.773
ENSG00000005436 E030 4.7428672 0.0032187783 0.952639312 0.98825179 2 75702313 75702423 111 - 0.758 0.754 -0.016
ENSG00000005436 E031 4.2528602 0.0034632899 0.858709382 0.95074481 2 75706523 75706651 129 - 0.725 0.706 -0.078
ENSG00000005436 E032 0.0000000       2 75710444 75710590 147 -      
ENSG00000005436 E033 3.0136554 0.0049010152 0.161766848 0.43004402 2 75710591 75710985 395 - 0.672 0.483 -0.855

Help

Please Click HERE to learn more details about the results from DEXseq.