ENSG00000005700

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000445419 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding retained_intron 18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 1.7006883 3.5317747 0.8325005 0.3092786 0.08190145 -2.071723 0.10146667 0.226375 0.038150 -0.188225 0.003107229 0.003107229 TRUE TRUE
ENST00000471036 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding nonsense_mediated_decay 18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 0.3379776 1.0139327 0.0000000 0.7837006 0.00000000 -6.677977 0.01931667 0.057950 0.000000 -0.057950 0.451023892 0.003107229 TRUE TRUE
ENST00000610980 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding protein_coding 18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 3.2832362 1.0559764 4.7033380 0.6172728 1.57350265 2.144574 0.16618333 0.071425 0.207250 0.135825 0.681417445 0.003107229 FALSE TRUE
MSTRG.24961.3 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding   18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 2.3515878 1.2835854 3.8151814 0.2530054 0.14477498 1.564153 0.12030833 0.081475 0.174025 0.092550 0.433365201 0.003107229 FALSE TRUE
MSTRG.24961.5 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding   18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 0.2865617 0.8596852 0.0000000 0.7075594 0.00000000 -6.442421 0.02060000 0.061800 0.000000 -0.061800 0.530316273 0.003107229 TRUE TRUE
MSTRG.24961.6 ENSG00000005700 No_inf pgKDN_inf IBTK protein_coding   18.76549 15.73202 22.01445 0.8784304 0.6817845 0.4844856 8.7282754 5.5285815 11.1838578 0.7849214 0.42515768 1.015119 0.45691667 0.350325 0.509950 0.159625 0.443332117 0.003107229 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000005700 E001 0.0000000       6 82169986 82169986 1 -      
ENSG00000005700 E002 0.5074773 0.0157942314 0.0188455560 0.122068193 6 82169987 82170098 112 - 0.000 0.336 11.665
ENSG00000005700 E003 0.3717469 0.0168121058 0.3896424474   6 82170099 82170108 10 - 0.081 0.199 1.504
ENSG00000005700 E004 1.0862264 0.0155875834 0.6269673202 0.839789448 6 82170109 82170235 127 - 0.349 0.273 -0.496
ENSG00000005700 E005 0.3634701 0.0168210235 0.8244061199   6 82170236 82170238 3 - 0.150 0.111 -0.496
ENSG00000005700 E006 74.6121873 0.0004815895 0.0127648344 0.094119095 6 82170239 82170742 504 - 1.836 1.920 0.282
ENSG00000005700 E007 102.4208722 0.0002176031 0.0002055183 0.004284664 6 82170743 82171402 660 - 1.963 2.066 0.346
ENSG00000005700 E008 10.6428811 0.0014444071 0.1293561386 0.381552856 6 82171403 82171411 9 - 1.002 1.131 0.471
ENSG00000005700 E009 18.7252808 0.0007824530 0.0370542283 0.185371422 6 82171412 82171507 96 - 1.226 1.365 0.485
ENSG00000005700 E010 13.9907879 0.0020244858 0.0168167747 0.113105865 6 82171508 82171556 49 - 1.083 1.267 0.656
ENSG00000005700 E011 20.8209223 0.0078988985 0.0791018264 0.288382205 6 82172380 82172512 133 - 1.276 1.401 0.436
ENSG00000005700 E012 0.6261456 0.0149612562 0.0813979503 0.293267645 6 82172513 82173366 854 - 0.081 0.336 2.504
ENSG00000005700 E013 15.5836304 0.0070531706 0.8947348501 0.965230240 6 82173367 82173438 72 - 1.221 1.208 -0.044
ENSG00000005700 E014 0.2438580 0.0164214784 0.7847138358   6 82173439 82173578 140 - 0.081 0.111 0.504
ENSG00000005700 E015 0.9903408 0.0117786747 0.2335411585 0.522430894 6 82174898 82175002 105 - 0.209 0.390 1.241
ENSG00000005700 E016 3.0141009 0.0047007509 0.1716548955 0.444285613 6 82175904 82176026 123 - 0.672 0.483 -0.859
ENSG00000005700 E017 24.9935645 0.0041465440 0.0133296661 0.096889786 6 82181879 82182028 150 - 1.338 1.492 0.532
ENSG00000005700 E018 20.3605539 0.0381583871 0.4850622842 0.748879375 6 82191073 82191216 144 - 1.303 1.354 0.175
ENSG00000005700 E019 0.4906372 0.0870731894 0.7299012669   6 82191217 82191330 114 - 0.150 0.199 0.504
ENSG00000005700 E020 1.3352184 0.0130436183 0.7439684220 0.898734935 6 82191331 82191786 456 - 0.387 0.336 -0.303
ENSG00000005700 E021 16.8021901 0.0257343328 0.1286994915 0.380469106 6 82191787 82191879 93 - 1.308 1.150 -0.559
ENSG00000005700 E022 17.1724072 0.0007881110 0.0442219246 0.205673905 6 82194479 82194595 117 - 1.312 1.167 -0.511
ENSG00000005700 E023 11.7727676 0.0011888190 0.4008920052 0.684123063 6 82194596 82194642 47 - 1.132 1.060 -0.257
ENSG00000005700 E024 14.5920750 0.0127170131 0.7845415972 0.916838543 6 82196298 82196401 104 - 1.199 1.176 -0.081
ENSG00000005700 E025 6.9613421 0.0546379907 0.6125414929 0.831512242 6 82196402 82196446 45 - 0.868 0.933 0.250
ENSG00000005700 E026 14.9531539 0.0090047870 0.7849522007 0.917109571 6 82200141 82200253 113 - 1.210 1.184 -0.091
ENSG00000005700 E027 15.4677924 0.0012005461 0.0316379014 0.168047919 6 82200587 82200708 122 - 1.276 1.112 -0.581
ENSG00000005700 E028 11.2263156 0.0014491591 0.0455483359 0.208823865 6 82201422 82201482 61 - 1.151 0.976 -0.638
ENSG00000005700 E029 19.9704027 0.0007972237 0.8400711919 0.942588222 6 82202528 82202645 118 - 1.312 1.325 0.043
ENSG00000005700 E030 17.0014674 0.0009072670 0.5096606431 0.767476304 6 82204857 82204958 102 - 1.271 1.224 -0.167
ENSG00000005700 E031 3.1228643 0.0045534701 0.0004900047 0.008597239 6 82204959 82205929 971 - 0.349 0.815 2.167
ENSG00000005700 E032 13.1932875 0.0101860572 0.2110281947 0.495823774 6 82210814 82210910 97 - 1.193 1.082 -0.398
ENSG00000005700 E033 9.6904770 0.0017096805 0.3591117811 0.648529995 6 82211367 82211404 38 - 1.060 0.976 -0.310
ENSG00000005700 E034 14.3760462 0.0009558103 0.0355767363 0.180669597 6 82211490 82211572 83 - 1.247 1.082 -0.588
ENSG00000005700 E035 11.8548896 0.0013050635 0.1230814243 0.371305802 6 82212707 82212788 82 - 1.157 1.026 -0.474
ENSG00000005700 E036 3.6348995 0.0193389764 0.6270504259 0.839793839 6 82212789 82212793 5 - 0.691 0.624 -0.284
ENSG00000005700 E037 37.4295063 0.0057040805 0.0554366618 0.234617854 6 82214227 82214829 603 - 1.624 1.516 -0.372
ENSG00000005700 E038 14.0778321 0.0045202616 0.2855785380 0.579190017 6 82216076 82216250 175 - 1.210 1.122 -0.313
ENSG00000005700 E039 13.1107875 0.0499213169 0.5383340267 0.787125443 6 82217960 82218137 178 - 1.182 1.092 -0.320
ENSG00000005700 E040 8.8456600 0.0373515432 0.3446883801 0.635822774 6 82220590 82220713 124 - 1.036 0.918 -0.438
ENSG00000005700 E041 10.4710757 0.0223381775 0.9375618591 0.982087053 6 82223440 82223620 181 - 1.052 1.060 0.030
ENSG00000005700 E042 9.4990777 0.0218235027 0.9774105559 0.996591478 6 82224068 82224185 118 - 1.019 1.014 -0.020
ENSG00000005700 E043 11.9075218 0.0011668215 0.6107790210 0.830684265 6 82225477 82225647 171 - 1.125 1.082 -0.155
ENSG00000005700 E044 0.0000000       6 82227164 82227191 28 -      
ENSG00000005700 E045 6.8903602 0.0140516803 0.2495687296 0.540528466 6 82227192 82227302 111 - 0.945 0.815 -0.496
ENSG00000005700 E046 6.9999704 0.0115215522 0.1291359578 0.381278740 6 82231718 82231842 125 - 0.965 0.796 -0.648
ENSG00000005700 E047 4.8213302 0.0240191271 0.1802026644 0.455633720 6 82234159 82234255 97 - 0.830 0.653 -0.718
ENSG00000005700 E048 25.2666488 0.0005791472 0.0087262699 0.073331667 6 82240166 82240843 678 - 1.477 1.319 -0.548
ENSG00000005700 E049 4.7136667 0.0030218742 0.1786149806 0.453508161 6 82247562 82247754 193 - 0.816 0.653 -0.666

Help

Please Click HERE to learn more details about the results from DEXseq.