ENSG00000006576

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307305 ENSG00000006576 No_inf pgKDN_inf PHTF2 protein_coding protein_coding 16.77035 18.46836 17.59283 0.9264331 0.9103569 -0.07002935 5.2116583 5.576401 6.093995 0.7402176 2.0541807 0.1278346 0.31492500 0.30710 0.362950 0.055850 1.00000000 0.04094766 FALSE  
ENST00000424760 ENSG00000006576 No_inf pgKDN_inf PHTF2 protein_coding protein_coding 16.77035 18.46836 17.59283 0.9264331 0.9103569 -0.07002935 0.6757885 0.000000 1.531016 0.0000000 0.6054883 7.2677383 0.03974167 0.00000 0.082625 0.082625 0.04885399 0.04094766 FALSE  
ENST00000454592 ENSG00000006576 No_inf pgKDN_inf PHTF2 protein_coding protein_coding_CDS_not_defined 16.77035 18.46836 17.59283 0.9264331 0.9103569 -0.07002935 0.4494729 1.015216 0.000000 0.3913834 0.0000000 -6.6797842 0.02543333 0.05260 0.000000 -0.052600 0.04094766 0.04094766 FALSE  
ENST00000470215 ENSG00000006576 No_inf pgKDN_inf PHTF2 protein_coding protein_coding_CDS_not_defined 16.77035 18.46836 17.59283 0.9264331 0.9103569 -0.07002935 8.6123606 10.589468 7.789455 1.1479678 0.8932988 -0.4425466 0.50935833 0.56885 0.438225 -0.130625 0.52603278 0.04094766 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000006576 E001 0.2452102 0.0163880788 0.9477266659   7 77798773 77798791 19 + 0.099 0.092 -0.121
ENSG00000006576 E002 0.1265070 0.0123337043 0.5854202094   7 77798792 77798804 13 + 0.000 0.092 11.087
ENSG00000006576 E003 0.3809057 0.0158960139 0.1203617537   7 77798805 77798812 8 + 0.000 0.232 12.572
ENSG00000006576 E004 2.2163581 0.0069448865 0.7725739480 0.912419047 7 77798813 77798887 75 + 0.483 0.525 0.201
ENSG00000006576 E005 2.0894427 0.0069883562 0.9463722504 0.985664316 7 77798888 77798900 13 + 0.483 0.493 0.049
ENSG00000006576 E006 3.4487666 0.0043412361 0.5973714967 0.823248015 7 77798901 77798971 71 + 0.609 0.677 0.294
ENSG00000006576 E007 0.0000000       7 77840130 77840179 50 +      
ENSG00000006576 E008 0.0000000       7 77840180 77840220 41 +      
ENSG00000006576 E009 3.7734649 0.0096130800 0.2697645400 0.563343815 7 77840221 77840300 80 + 0.748 0.608 -0.590
ENSG00000006576 E010 0.1271363 0.0123215564 0.5855705308   7 77854733 77854834 102 + 0.000 0.092 11.087
ENSG00000006576 E011 4.4968115 0.0640644364 0.2424770511 0.532145737 7 77893608 77893664 57 + 0.820 0.655 -0.672
ENSG00000006576 E012 0.0000000       7 77893982 77893993 12 +      
ENSG00000006576 E013 5.9552230 0.0024535735 0.0624418938 0.251134990 7 77900711 77900780 70 + 0.937 0.737 -0.780
ENSG00000006576 E014 8.7058667 0.0016409995 0.0005695058 0.009659034 7 77901762 77901920 159 + 1.131 0.806 -1.212
ENSG00000006576 E015 0.7507977 0.1624525062 0.1617053736 0.430007771 7 77906261 77906496 236 + 0.099 0.337 2.201
ENSG00000006576 E016 1.1228916 0.0106745508 0.1151890416 0.357746377 7 77907854 77907983 130 + 0.179 0.422 1.687
ENSG00000006576 E017 8.6620060 0.0016434638 0.1550127094 0.420673014 7 77908793 77908934 142 + 1.050 0.918 -0.488
ENSG00000006576 E018 4.1571626 0.0036256685 0.5584295783 0.800101269 7 77908935 77908958 24 + 0.748 0.677 -0.291
ENSG00000006576 E019 0.3806233 0.0159149350 0.1202984728   7 77908959 77910244 1286 + 0.000 0.232 12.572
ENSG00000006576 E020 10.5841091 0.0052438726 0.0320353226 0.169275310 7 77910245 77910409 165 + 1.154 0.965 -0.692
ENSG00000006576 E021 8.6701503 0.0016740504 0.3427576606 0.634132318 7 77920279 77920424 146 + 1.029 0.942 -0.324
ENSG00000006576 E022 6.1323382 0.0163698215 0.9985915239 1.000000000 7 77920425 77920465 41 + 0.853 0.851 -0.005
ENSG00000006576 E023 9.2264747 0.0186172131 0.5647509300 0.803920922 7 77922623 77922778 156 + 0.974 1.036 0.227
ENSG00000006576 E024 3.1895137 0.1510930260 0.9652735558 0.992727517 7 77922779 77924151 1373 + 0.609 0.632 0.103
ENSG00000006576 E025 13.4825167 0.0232247266 0.7891122623 0.919047071 7 77929109 77929327 219 + 1.170 1.151 -0.068
ENSG00000006576 E026 6.8250108 0.0027857755 0.2666611043 0.560078809 7 77937710 77937838 129 + 0.950 0.837 -0.431
ENSG00000006576 E027 0.3809057 0.0158960139 0.1203617537   7 77937839 77938013 175 + 0.000 0.232 12.572
ENSG00000006576 E028 9.7127739 0.0248656222 0.0459173121 0.209944414 7 77940030 77940198 169 + 1.130 0.918 -0.781
ENSG00000006576 E029 6.5739426 0.0338463490 0.2317398972 0.520446271 7 77940199 77940302 104 + 0.950 0.806 -0.551
ENSG00000006576 E030 0.7164944 0.0141953211 0.0754215751 0.280498361 7 77940303 77940459 157 + 0.357 0.092 -2.443
ENSG00000006576 E031 8.1156028 0.0095953354 0.5505420669 0.794845761 7 77940528 77940659 132 + 0.924 0.986 0.231
ENSG00000006576 E032 9.8137887 0.0014439310 0.8757507326 0.957718075 7 77942700 77942786 87 + 1.040 1.026 -0.048
ENSG00000006576 E033 15.3531853 0.0008998111 0.7398879759 0.896869909 7 77949678 77949833 156 + 1.199 1.223 0.087
ENSG00000006576 E034 9.8585054 0.0105477550 0.2682312678 0.561751454 7 77951617 77951712 96 + 0.974 1.080 0.389
ENSG00000006576 E035 10.7294882 0.0012955069 0.1521077999 0.415844590 7 77953769 77953894 126 + 0.997 1.121 0.451
ENSG00000006576 E036 230.4089713 0.0001260424 0.0025121123 0.030229421 7 77954858 77957503 2646 + 2.340 2.381 0.137

Help

Please Click HERE to learn more details about the results from DEXseq.