ENSG00000006744

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338034 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding protein_coding 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 2.1586937 2.4045517 2.42246636 0.09273249 0.22475750 0.01066451 0.15225833 0.219675 0.134950 -0.084725 0.626384288 0.001016208 FALSE TRUE
ENST00000395962 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding protein_coding 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 7.8713800 3.6593388 11.03346006 0.47999094 0.50962895 1.58960023 0.50065000 0.333150 0.605875 0.272725 0.070153820 0.001016208 FALSE TRUE
ENST00000426905 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding protein_coding 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 1.4360153 0.7677602 0.80925166 0.48514921 0.46722268 0.07498123 0.09761667 0.076250 0.048125 -0.028125 0.971980984 0.001016208 FALSE TRUE
ENST00000487229 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding retained_intron 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 0.4779379 0.8686244 0.08541031 0.46444813 0.08541031 -3.20302948 0.03717500 0.075450 0.004225 -0.071225 0.260940838 0.001016208 FALSE TRUE
ENST00000491478 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding retained_intron 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 0.5808440 1.2512977 0.00000000 0.30007445 0.00000000 -6.97876502 0.04732500 0.113650 0.000000 -0.113650 0.001016208 0.001016208 FALSE FALSE
ENST00000578071 ENSG00000006744 No_inf pgKDN_inf ELAC2 protein_coding protein_coding 15.09715 10.97385 18.29423 0.5191316 0.9124043 0.7367931 0.8994493 0.4972539 2.20109406 0.49725388 1.27167117 2.12398050 0.05120000 0.042075 0.111525 0.069450 0.833354664 0.001016208 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000006744 E001 6.1271512 0.0023478201 0.087983434 0.30765680 17 12991612 12992390 779 - 0.764 0.943 0.695
ENSG00000006744 E002 0.7254019 0.0139573218 0.738300383 0.89612902 17 12992391 12992391 1 - 0.255 0.204 -0.420
ENSG00000006744 E003 0.7254019 0.0139573218 0.738300383 0.89612902 17 12992392 12992392 1 - 0.255 0.204 -0.420
ENSG00000006744 E004 11.4829825 0.0013152351 0.179234658 0.45433294 17 12992393 12992559 167 - 1.042 1.151 0.395
ENSG00000006744 E005 9.6722576 0.0014803600 0.091284329 0.31384771 17 12992560 12992610 51 - 0.955 1.103 0.543
ENSG00000006744 E006 43.7514614 0.0005848413 0.907622097 0.97067573 17 12992611 12993045 435 - 1.644 1.647 0.011
ENSG00000006744 E007 14.4559844 0.0009831360 0.026631897 0.15129184 17 12993687 12993831 145 - 1.108 1.271 0.580
ENSG00000006744 E008 4.8074495 0.0041280684 0.018384268 0.11989566 17 12994425 12994429 5 - 0.624 0.897 1.103
ENSG00000006744 E009 10.4260801 0.0013582344 0.028133396 0.15679928 17 12994430 12994503 74 - 0.964 1.151 0.682
ENSG00000006744 E010 14.7599043 0.0009466842 0.142221108 0.40122153 17 12994764 12994884 121 - 1.236 1.123 -0.403
ENSG00000006744 E011 0.8802322 0.0122996029 0.013316919 0.09681018 17 12994885 12994962 78 - 0.079 0.446 3.165
ENSG00000006744 E012 11.2578777 0.0227702817 0.351832816 0.64198359 17 12994963 12995062 100 - 1.121 1.024 -0.351
ENSG00000006744 E013 11.4692169 0.0012528122 0.353231190 0.64300050 17 12995703 12995812 110 - 1.057 1.133 0.272
ENSG00000006744 E014 7.0365039 0.0043442762 0.563313360 0.80269645 17 12995940 12995978 39 - 0.925 0.862 -0.237
ENSG00000006744 E015 1.8313299 0.0074223837 0.603496251 0.82699604 17 12995979 12996546 568 - 0.415 0.491 0.387
ENSG00000006744 E016 12.0923807 0.0126952058 0.140972594 0.39943346 17 12996547 12996685 139 - 1.165 1.024 -0.508
ENSG00000006744 E017 6.6493563 0.0038252837 0.271485549 0.56523490 17 12998412 12998448 37 - 0.925 0.805 -0.460
ENSG00000006744 E018 7.6423224 0.0270016575 0.620273420 0.83580239 17 12998449 12998508 60 - 0.955 0.897 -0.219
ENSG00000006744 E019 5.2287826 0.0209787364 0.964814408 0.99259340 17 13000156 13000176 21 - 0.793 0.784 -0.034
ENSG00000006744 E020 6.6919433 0.0278406244 0.975994949 0.99597577 17 13000177 13000224 48 - 0.881 0.880 -0.006
ENSG00000006744 E021 6.0578617 0.0208470636 0.624124458 0.83826896 17 13000225 13000274 50 - 0.870 0.805 -0.250
ENSG00000006744 E022 1.6075803 0.0084698118 0.121398040 0.36877902 17 13000275 13000897 623 - 0.301 0.531 1.258
ENSG00000006744 E023 10.0980087 0.0013850047 0.855582512 0.94916702 17 13002274 13002359 86 - 1.034 1.048 0.052
ENSG00000006744 E024 0.3729758 0.2239485367 0.412976565   17 13002360 13002440 81 - 0.079 0.204 1.579
ENSG00000006744 E025 5.7465881 0.0024741316 0.345986868 0.63690749 17 13002441 13002445 5 - 0.779 0.880 0.395
ENSG00000006744 E026 11.4775963 0.0020044841 0.258419889 0.55079328 17 13002446 13002579 134 - 1.050 1.142 0.334
ENSG00000006744 E027 0.1187032 0.0118452944 0.819146032   17 13002580 13002725 146 - 0.079 0.000 -7.981
ENSG00000006744 E028 0.0000000       17 13003450 13003478 29 -      
ENSG00000006744 E029 4.4624483 0.0033976156 0.198351173 0.47976824 17 13003479 13003499 21 - 0.793 0.633 -0.661
ENSG00000006744 E030 4.2233428 0.0057956732 0.303557317 0.59691047 17 13003500 13003505 6 - 0.764 0.633 -0.546
ENSG00000006744 E031 5.5565980 0.0027264346 0.304040159 0.59753314 17 13003506 13003548 43 - 0.858 0.739 -0.468
ENSG00000006744 E032 4.8317641 0.0200092598 0.353384872 0.64313079 17 13003549 13003574 26 - 0.807 0.689 -0.475
ENSG00000006744 E033 1.1328379 0.0116999201 0.002473247 0.02986836 17 13003575 13004108 534 - 0.079 0.531 3.580
ENSG00000006744 E034 7.4844987 0.0019978577 0.127888106 0.37905949 17 13004989 13005101 113 - 0.983 0.825 -0.599
ENSG00000006744 E035 0.3614886 0.0165468943 0.871343847   17 13005102 13005110 9 - 0.146 0.114 -0.420
ENSG00000006744 E036 3.7914549 0.0039693354 0.347267717 0.63784011 17 13005753 13005771 19 - 0.624 0.739 0.487
ENSG00000006744 E037 5.3909454 0.0027122900 0.181591576 0.45759753 17 13005772 13005825 54 - 0.733 0.880 0.580
ENSG00000006744 E038 5.7327665 0.0030227666 0.516081108 0.77182860 17 13005921 13005979 59 - 0.793 0.862 0.272
ENSG00000006744 E039 0.8686190 0.0129155487 0.095732622 0.32221937 17 13005980 13006546 567 - 0.146 0.397 1.902
ENSG00000006744 E040 3.7475865 0.0239419136 0.409690938 0.69188633 17 13010613 13010617 5 - 0.716 0.601 -0.491
ENSG00000006744 E041 4.1073760 0.0366189233 0.425086698 0.70419605 17 13010618 13010671 54 - 0.748 0.633 -0.484
ENSG00000006744 E042 3.2548401 0.0044614756 0.266968586 0.56023978 17 13011663 13011686 24 - 0.682 0.531 -0.668
ENSG00000006744 E043 2.4107740 0.0060040595 0.357635809 0.64720866 17 13011687 13011692 6 - 0.580 0.446 -0.643
ENSG00000006744 E044 3.8697564 0.0066842195 0.521498048 0.77536431 17 13011693 13011723 31 - 0.716 0.633 -0.353
ENSG00000006744 E045 6.0436276 0.0024803252 0.245291935 0.53573199 17 13011724 13011782 59 - 0.893 0.763 -0.508
ENSG00000006744 E046 8.0704287 0.0017173956 0.024688812 0.14443719 17 13013207 13013275 69 - 1.034 0.805 -0.865
ENSG00000006744 E047 6.0150086 0.0022544327 0.038678997 0.19025302 17 13014439 13014496 58 - 0.925 0.689 -0.929
ENSG00000006744 E048 7.0075893 0.0020483740 0.158645061 0.42575389 17 13015768 13015832 65 - 0.955 0.805 -0.572
ENSG00000006744 E049 7.2601585 0.0019499432 0.288475372 0.58202270 17 13016862 13016925 64 - 0.955 0.844 -0.420
ENSG00000006744 E050 2.6783159 0.0664383119 0.928890489 0.97898311 17 13016926 13016932 7 - 0.557 0.567 0.048
ENSG00000006744 E051 3.8006458 0.0042663148 0.195900510 0.47636150 17 13017071 13017098 28 - 0.602 0.762 0.673
ENSG00000006744 E052 3.2026074 0.0050691491 0.072068146 0.27225071 17 13017099 13017121 23 - 0.505 0.739 1.027
ENSG00000006744 E053 0.0000000       17 13017122 13017412 291 -      
ENSG00000006744 E054 0.0000000       17 13017413 13017496 84 -      
ENSG00000006744 E055 0.0000000       17 13017497 13017566 70 -      
ENSG00000006744 E056 0.0000000       17 13017567 13017581 15 -      
ENSG00000006744 E057 0.0000000       17 13017582 13017683 102 -      
ENSG00000006744 E058 3.5400816 0.0040232490 0.599258816 0.82431138 17 13017703 13017736 34 - 0.624 0.689 0.280
ENSG00000006744 E059 10.0493091 0.0512930842 0.484842497 0.74881863 17 13017737 13017990 254 - 1.072 0.986 -0.317
ENSG00000006744 E060 0.8414621 0.0272941615 0.537864681 0.78681802 17 13017991 13018065 75 - 0.301 0.204 -0.742

Help

Please Click HERE to learn more details about the results from DEXseq.