ENSG00000008294

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262013 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding protein_coding 41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 4.083623 5.483231 3.512261 1.876103 1.3156675 -0.6411533 0.10906667 0.183025 0.072525 -0.110500 7.975494e-01 1.197291e-15 FALSE TRUE
ENST00000357122 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding protein_coding 41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 9.586925 0.000000 14.543428 0.000000 1.4821314 10.5071433 0.20510000 0.000000 0.293525 0.293525 1.197291e-15 1.197291e-15 FALSE TRUE
MSTRG.12946.10 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 3.314174 5.035839 0.000000 1.248170 0.0000000 -8.9789503 0.09268333 0.167625 0.000000 -0.167625 1.645910e-07 1.197291e-15 TRUE TRUE
MSTRG.12946.11 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 1.242149 0.000000 3.726447 0.000000 2.1622260 8.5455231 0.02372500 0.000000 0.071175 0.071175 5.390891e-01 1.197291e-15 TRUE TRUE
MSTRG.12946.13 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 5.021122 4.155920 6.529414 1.673445 0.8795242 0.6505264 0.12039167 0.134250 0.132100 -0.002150 9.313005e-01 1.197291e-15 FALSE TRUE
MSTRG.12946.2 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 6.944866 3.040316 11.200676 1.833369 0.8510765 1.8778429 0.15845833 0.102125 0.223100 0.120975 4.515004e-01 1.197291e-15 FALSE TRUE
MSTRG.12946.4 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 4.813136 5.969116 4.666613 1.448137 1.6367465 -0.3544680 0.12815833 0.199175 0.098600 -0.100575 7.562677e-01 1.197291e-15 TRUE TRUE
MSTRG.12946.5 ENSG00000008294 No_inf pgKDN_inf SPAG9 protein_coding   41.70492 30.37628 50.09434 1.131719 2.850792 0.7215155 2.305216 3.074683 1.309324 1.649820 0.9080751 -1.2253236 0.05993333 0.099375 0.023675 -0.075700 6.904758e-01 1.197291e-15 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000008294 E001 0.0000000       17 50962174 50962175 2 -      
ENSG00000008294 E002 0.1186381 0.0118272110 7.178385e-01   17 50962176 50962199 24 - 0.083 0.000 -10.190
ENSG00000008294 E003 0.2459004 0.0163576473 8.223240e-01   17 50962200 50962202 3 - 0.083 0.109 0.436
ENSG00000008294 E004 217.2378455 0.0001127111 3.608928e-08 2.303479e-06 17 50962203 50964148 1946 - 2.282 2.396 0.379
ENSG00000008294 E005 24.2211724 0.0014825345 1.188725e-01 3.643802e-01 17 50964149 50964394 246 - 1.352 1.452 0.348
ENSG00000008294 E006 41.9634979 0.0047410816 4.879740e-02 2.176693e-01 17 50964395 50965059 665 - 1.578 1.689 0.377
ENSG00000008294 E007 6.9957382 0.0019897076 1.412314e-01 3.998123e-01 17 50965060 50965074 15 - 0.825 0.980 0.588
ENSG00000008294 E008 47.7365081 0.0003126063 1.090111e-02 8.509896e-02 17 50965075 50965626 552 - 1.630 1.746 0.392
ENSG00000008294 E009 7.8586993 0.0261558935 1.592131e-01 4.265658e-01 17 50965627 50965643 17 - 0.864 1.029 0.616
ENSG00000008294 E010 171.9620673 0.0001196627 6.877376e-02 2.648325e-01 17 50965644 50966299 656 - 2.214 2.260 0.154
ENSG00000008294 E011 35.2282484 0.0073443181 7.647774e-01 9.085086e-01 17 50966300 50966387 88 - 1.545 1.570 0.085
ENSG00000008294 E012 45.9401190 0.0004544876 7.118425e-01 8.834878e-01 17 50970707 50970856 150 - 1.659 1.681 0.074
ENSG00000008294 E013 37.8177587 0.0003652727 3.492102e-01 6.395993e-01 17 50974771 50974869 99 - 1.604 1.563 -0.137
ENSG00000008294 E014 32.5982308 0.0004155730 4.043590e-01 6.871262e-01 17 50974870 50974947 78 - 1.540 1.502 -0.131
ENSG00000008294 E015 46.6286342 0.0080516120 4.464859e-13 6.096398e-11 17 50974948 50975862 915 - 1.433 1.862 1.459
ENSG00000008294 E016 12.2981123 0.0011086691 8.825447e-03 7.394620e-02 17 50975863 50975901 39 - 1.011 1.229 0.784
ENSG00000008294 E017 35.7953469 0.0126337698 1.212812e-08 8.528266e-07 17 50975902 50976599 698 - 1.343 1.739 1.354
ENSG00000008294 E018 26.7827388 0.0175449013 3.517841e-07 1.815610e-05 17 50976600 50977107 508 - 1.208 1.623 1.436
ENSG00000008294 E019 29.5468667 0.0035034952 4.652686e-01 7.343722e-01 17 50977108 50977221 114 - 1.498 1.461 -0.129
ENSG00000008294 E020 13.5127813 0.0010082530 7.706942e-01 9.115077e-01 17 50979746 50979761 16 - 1.167 1.149 -0.063
ENSG00000008294 E021 37.9607848 0.0003706014 5.216714e-01 7.754548e-01 17 50979762 50979917 156 - 1.599 1.573 -0.088
ENSG00000008294 E022 41.0524971 0.0003241964 1.037942e-01 3.367093e-01 17 50982524 50982672 149 - 1.651 1.580 -0.242
ENSG00000008294 E023 28.2736335 0.0005565780 6.807381e-02 2.632205e-01 17 50984923 50984990 68 - 1.504 1.406 -0.337
ENSG00000008294 E024 16.5324943 0.0008410812 2.049449e-03 2.603273e-02 17 50985698 50985698 1 - 1.326 1.103 -0.791
ENSG00000008294 E025 27.3449185 0.0005731365 4.987235e-03 4.952588e-02 17 50985699 50985778 80 - 1.513 1.355 -0.545
ENSG00000008294 E026 34.0557975 0.0004044517 4.768738e-01 7.432368e-01 17 50987112 50987237 126 - 1.556 1.524 -0.106
ENSG00000008294 E027 0.1187032 0.0118317626 7.178812e-01   17 50989540 50989638 99 - 0.083 0.000 -12.899
ENSG00000008294 E028 0.3549719 0.0157267217 1.720579e-01   17 50989639 50989676 38 - 0.213 0.000 -14.391
ENSG00000008294 E029 41.4568224 0.0004494795 3.243970e-01 6.167800e-01 17 50989677 50989827 151 - 1.643 1.602 -0.138
ENSG00000008294 E030 17.3991798 0.0173922347 7.625859e-01 9.073709e-01 17 50989828 50989872 45 - 1.271 1.250 -0.074
ENSG00000008294 E031 0.0000000       17 50990023 50990164 142 -      
ENSG00000008294 E032 0.1186381 0.0118272110 7.178385e-01   17 50990327 50990449 123 - 0.083 0.000 -12.899
ENSG00000008294 E033 42.7172129 0.0004297916 5.600027e-02 2.358190e-01 17 50990450 50990668 219 - 1.673 1.590 -0.284
ENSG00000008294 E034 0.2545247 0.2863274579 2.136424e-01   17 50990669 50990742 74 - 0.000 0.196 12.528
ENSG00000008294 E035 9.2906362 0.0052107779 2.509327e-02 1.457285e-01 17 50993764 50993772 9 - 1.092 0.878 -0.795
ENSG00000008294 E036 35.9342617 0.0050442812 1.627843e-01 4.313244e-01 17 50993773 50993935 163 - 1.597 1.521 -0.260
ENSG00000008294 E037 0.1176306 0.0117672168 7.178729e-01   17 50993936 50993937 2 - 0.083 0.000 -12.900
ENSG00000008294 E038 45.8822225 0.0003793933 7.898444e-02 2.881847e-01 17 50995057 50995224 168 - 1.699 1.626 -0.248
ENSG00000008294 E039 23.9769349 0.0182303390 6.769816e-01 8.661023e-01 17 50995444 50995533 90 - 1.409 1.376 -0.113
ENSG00000008294 E040 2.3497313 0.2074720381 2.498169e-01 5.407820e-01 17 50995534 50995960 427 - 0.393 0.645 1.215
ENSG00000008294 E041 1.7446605 0.1058339137 7.610357e-02 2.819104e-01 17 50996229 50996564 336 - 0.265 0.585 1.758
ENSG00000008294 E042 25.8606196 0.0058906879 1.360935e-01 3.923073e-01 17 50996565 50996694 130 - 1.465 1.371 -0.327
ENSG00000008294 E043 0.2362687 0.0156871607 3.583241e-01   17 50998413 50998443 31 - 0.153 0.000 -13.829
ENSG00000008294 E044 35.1326875 0.0047766276 3.119613e-01 6.053363e-01 17 50998444 50998617 174 - 1.578 1.524 -0.183
ENSG00000008294 E045 0.1176306 0.0117672168 7.178729e-01   17 50999476 50999487 12 - 0.083 0.000 -12.900
ENSG00000008294 E046 23.6199031 0.0006025283 2.446673e-02 1.435272e-01 17 50999661 50999717 57 - 1.443 1.309 -0.465
ENSG00000008294 E047 40.1342104 0.0003734673 1.522826e-02 1.062656e-01 17 51001715 51001834 120 - 1.657 1.546 -0.378
ENSG00000008294 E048 17.3471172 0.0007935263 1.648214e-01 4.342898e-01 17 51001835 51001836 2 - 1.300 1.207 -0.328
ENSG00000008294 E049 16.7053535 0.0009369392 3.729770e-02 1.859456e-01 17 51001837 51001845 9 - 1.304 1.158 -0.517
ENSG00000008294 E050 23.8110029 0.0006959254 1.186240e-03 1.705188e-02 17 51005212 51005263 52 - 1.469 1.271 -0.687
ENSG00000008294 E051 42.9039906 0.0010313118 3.666608e-03 3.999086e-02 17 51006085 51006237 153 - 1.694 1.560 -0.455
ENSG00000008294 E052 21.7924290 0.0051670537 5.181937e-02 2.259723e-01 17 51007269 51007326 58 - 1.409 1.277 -0.457
ENSG00000008294 E053 0.0000000       17 51007837 51007851 15 -      
ENSG00000008294 E054 0.0000000       17 51009131 51009142 12 -      
ENSG00000008294 E055 26.4842156 0.0166026077 4.756351e-02 2.144013e-01 17 51014232 51014353 122 - 1.498 1.344 -0.534
ENSG00000008294 E056 0.0000000       17 51014454 51014653 200 -      
ENSG00000008294 E057 0.0000000       17 51016226 51016256 31 -      
ENSG00000008294 E058 22.1813330 0.0007648505 6.493687e-02 2.567290e-01 17 51020159 51020258 100 - 1.409 1.296 -0.390
ENSG00000008294 E059 0.0000000       17 51020259 51020259 1 -      
ENSG00000008294 E060 19.6668272 0.0006938375 2.426147e-01 5.322207e-01 17 51021158 51021251 94 - 1.343 1.271 -0.254
ENSG00000008294 E061 18.9539886 0.0013369549 1.929454e-03 2.488359e-02 17 51021252 51021365 114 - 1.379 1.166 -0.747
ENSG00000008294 E062 0.2537079 0.3070364544 2.173645e-01   17 51030914 51031442 529 - 0.000 0.196 12.498
ENSG00000008294 E063 0.4886249 0.0158562243 7.744485e-01   17 51031443 51031680 238 - 0.153 0.196 0.436
ENSG00000008294 E064 3.2247291 0.1734007356 5.570970e-02 2.351974e-01 17 51031681 51031722 42 - 0.750 0.384 -1.700
ENSG00000008294 E065 0.0000000       17 51040428 51040451 24 -      
ENSG00000008294 E066 23.2979001 0.0053349696 2.262334e-01 5.142527e-01 17 51041501 51041651 151 - 1.416 1.338 -0.269
ENSG00000008294 E067 0.1272623 0.0123465117 4.007677e-01   17 51046500 51046878 379 - 0.000 0.109 12.545
ENSG00000008294 E068 17.4503757 0.0007657946 7.206086e-02 2.722507e-01 17 51047375 51047469 95 - 1.313 1.191 -0.431
ENSG00000008294 E069 0.1187032 0.0118317626 7.178812e-01   17 51047470 51047471 2 - 0.083 0.000 -12.899
ENSG00000008294 E070 0.1272623 0.0123465117 4.007677e-01   17 51052748 51052801 54 - 0.000 0.109 12.545
ENSG00000008294 E071 16.8854527 0.0017580917 3.530287e-01 6.428737e-01 17 51056412 51056482 71 - 1.276 1.214 -0.219
ENSG00000008294 E072 22.1102144 0.0106543897 3.277211e-01 6.203014e-01 17 51079584 51079704 121 - 1.390 1.321 -0.242
ENSG00000008294 E073 26.1799829 0.0155182806 1.871152e-03 2.430604e-02 17 51120354 51120868 515 - 1.524 1.277 -0.854

Help

Please Click HERE to learn more details about the results from DEXseq.