ENSG00000008517

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000008180 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.1839191 0.0000000 0.5517573 0.0000000 0.4296314 5.811875 0.01829167 0.000000 0.054875 0.054875 0.61847620 0.04609402 FALSE TRUE
ENST00000440815 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.2407634 0.5954828 0.0000000 0.5954828 0.0000000 -5.920014 0.02460833 0.059375 0.000000 -0.059375 0.85411605 0.04609402 FALSE TRUE
ENST00000525003 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding retained_intron 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.9303908 1.8363754 0.0000000 1.8363754 0.0000000 -7.528552 0.07567500 0.123375 0.000000 -0.123375 0.84658493 0.04609402 FALSE FALSE
ENST00000525228 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.2849316 0.8547949 0.0000000 0.5417648 0.0000000 -6.434286 0.02612500 0.078375 0.000000 -0.078375 0.52333278 0.04609402 FALSE FALSE
ENST00000529550 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 1.6416130 0.8950946 1.9636264 0.8950946 1.9636264 1.124708 0.15390000 0.060150 0.166000 0.105850 1.00000000 0.04609402 FALSE TRUE
ENST00000529699 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 1.0814535 0.0000000 1.9983537 0.0000000 0.9696878 7.649870 0.08729167 0.000000 0.146675 0.146675 0.04609402 0.04609402 FALSE TRUE
ENST00000530538 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 2.9199419 2.3148658 6.4449598 2.3148658 2.5230536 1.473261 0.24673333 0.217025 0.523175 0.306150 0.24187912 0.04609402 FALSE TRUE
ENST00000531965 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.6290693 1.0091188 0.0000000 1.0091188 0.0000000 -6.671178 0.06121667 0.088325 0.000000 -0.088325 0.85260370 0.04609402 FALSE TRUE
ENST00000548246 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.9877635 0.6151525 0.0000000 0.6151525 0.0000000 -5.966136 0.08191667 0.053850 0.000000 -0.053850 0.84956130 0.04609402 FALSE TRUE
ENST00000552664 ENSG00000008517 No_inf pgKDN_inf IL32 protein_coding protein_coding 11.3946 11.75073 12.17442 1.082632 1.733894 0.05106018 0.9170185 1.6211889 0.0000000 1.6211889 0.0000000 -7.349780 0.08870833 0.161650 0.000000 -0.161650 0.86398391 0.04609402 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000008517 E001 0.1186381 0.012429109 0.776171953   16 3065297 3065311 15 + 0.082 0.000 -10.734
ENSG00000008517 E002 0.2459004 0.016799708 0.789407006   16 3065312 3065321 10 + 0.082 0.110 0.485
ENSG00000008517 E003 0.2459004 0.016799708 0.789407006   16 3065322 3065354 33 + 0.082 0.110 0.485
ENSG00000008517 E004 0.2459004 0.016799708 0.789407006   16 3065355 3065357 3 + 0.082 0.110 0.485
ENSG00000008517 E005 0.2459004 0.016799708 0.789407006   16 3065358 3065368 11 + 0.082 0.110 0.485
ENSG00000008517 E006 0.3646036 0.017000215 0.831384243   16 3065369 3065376 8 + 0.150 0.110 -0.515
ENSG00000008517 E007 0.7360062 0.015150900 0.677944775 0.8666821 16 3065377 3065379 3 + 0.210 0.272 0.485
ENSG00000008517 E008 0.6173681 0.016722354 0.408475433 0.6907696 16 3065380 3065391 12 + 0.150 0.272 1.070
ENSG00000008517 E009 0.4901058 0.016748186 0.731772553   16 3065392 3065403 12 + 0.150 0.198 0.485
ENSG00000008517 E010 0.6087439 0.015365712 0.947278557 0.9860370 16 3065404 3065411 8 + 0.210 0.198 -0.100
ENSG00000008517 E011 1.2059397 0.010961898 0.448943169 0.7228882 16 3065412 3065494 83 + 0.389 0.272 -0.737
ENSG00000008517 E012 0.1170040 0.012339564 0.776142177   16 3065495 3065609 115 + 0.082 0.000 -13.146
ENSG00000008517 E013 0.0000000       16 3065610 3065613 4 +      
ENSG00000008517 E014 0.0000000       16 3065614 3065620 7 +      
ENSG00000008517 E015 0.0000000       16 3065621 3065630 10 +      
ENSG00000008517 E016 0.0000000       16 3065631 3065638 8 +      
ENSG00000008517 E017 0.0000000       16 3065639 3065639 1 +      
ENSG00000008517 E018 0.0000000       16 3065640 3065640 1 +      
ENSG00000008517 E019 0.0000000       16 3065641 3065641 1 +      
ENSG00000008517 E020 0.1187032 0.012064263 0.776449872   16 3065642 3065652 11 + 0.082 0.000 -13.147
ENSG00000008517 E021 0.1187032 0.012064263 0.776449872   16 3065653 3065653 1 + 0.082 0.000 -13.147
ENSG00000008517 E022 0.2363338 0.016106206 0.390950331   16 3065654 3065655 2 + 0.150 0.000 -13.868
ENSG00000008517 E023 0.2363338 0.016106206 0.390950331   16 3065656 3065661 6 + 0.150 0.000 -13.868
ENSG00000008517 E024 0.2363338 0.016106206 0.390950331   16 3065662 3065662 1 + 0.150 0.000 -13.868
ENSG00000008517 E025 0.7276653 0.014484611 0.681623267 0.8682781 16 3065663 3065676 14 + 0.262 0.198 -0.515
ENSG00000008517 E026 0.8463035 0.013794370 0.478047440 0.7441843 16 3065677 3065687 11 + 0.308 0.198 -0.837
ENSG00000008517 E027 0.6271531 0.015454309 0.081826494 0.2942397 16 3065688 3065710 23 + 0.082 0.334 2.485
ENSG00000008517 E028 0.6271531 0.015454309 0.081826494 0.2942397 16 3065711 3065711 1 + 0.082 0.334 2.485
ENSG00000008517 E029 0.6271531 0.015454309 0.081826494 0.2942397 16 3065712 3065780 69 + 0.082 0.334 2.485
ENSG00000008517 E030 0.6090882 0.014986018 0.944937972 0.9847981 16 3065781 3065783 3 + 0.210 0.198 -0.100
ENSG00000008517 E031 1.8054586 0.008497988 0.227373096 0.5157347 16 3065784 3065811 28 + 0.515 0.334 -0.974
ENSG00000008517 E032 2.2874408 0.007238431 0.163304366 0.4320656 16 3065812 3065826 15 + 0.591 0.389 -1.000
ENSG00000008517 E033 2.2802324 0.006673015 0.056514997 0.2372229 16 3067377 3067415 39 + 0.613 0.334 -1.422
ENSG00000008517 E034 0.1176306 0.012175898 0.776202192   16 3067416 3067442 27 + 0.082 0.000 -13.147
ENSG00000008517 E035 0.3522653 0.040881826 0.195051594   16 3067443 3067553 111 + 0.210 0.000 -14.244
ENSG00000008517 E036 4.3726283 0.003791432 0.737239831 0.8958600 16 3067554 3067613 60 + 0.744 0.704 -0.167
ENSG00000008517 E037 0.1268540 0.012492747 0.374326790   16 3067614 3067803 190 + 0.000 0.110 12.879
ENSG00000008517 E038 0.3628408 0.017631561 0.832879268   16 3067804 3067983 180 + 0.150 0.110 -0.515
ENSG00000008517 E039 4.3662747 0.003785710 0.486375293 0.7500476 16 3067984 3068010 27 + 0.760 0.678 -0.338
ENSG00000008517 E040 0.3629044 0.017525067 0.830147872   16 3068011 3068117 107 + 0.150 0.110 -0.515
ENSG00000008517 E041 0.0000000       16 3068118 3068179 62 +      
ENSG00000008517 E042 3.0332054 0.006777981 0.562059189 0.8021157 16 3068180 3068239 60 + 0.635 0.557 -0.345
ENSG00000008517 E043 0.0000000       16 3068240 3068665 426 +      
ENSG00000008517 E044 0.0000000       16 3068990 3069109 120 +      
ENSG00000008517 E045 4.9997340 0.066643642 0.579764858 0.8123717 16 3069110 3069280 171 + 0.744 0.813 0.275
ENSG00000008517 E046 8.9309545 0.002139273 0.141126204 0.3997336 16 3069281 3069522 242 + 0.937 1.058 0.446
ENSG00000008517 E047 0.9999116 0.013110076 0.055160274 0.2339583 16 3069523 3069819 297 + 0.150 0.437 2.070
ENSG00000008517 E048 0.7619374 0.046461439 0.003162362 0.0358920 16 3081633 3082192 560 + 0.000 0.437 14.848

Help

Please Click HERE to learn more details about the results from DEXseq.