ENSG00000010295

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356896 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding protein_coding 17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 3.8547975 4.7994246 4.0044380 2.2274690 1.6956592 -0.26066624 0.21630833 0.206600 0.281825 0.075225 0.931412806 0.006372943 FALSE TRUE
ENST00000396830 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding retained_intron 17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 2.9644507 2.1877978 3.2198050 1.4333086 1.8812195 0.55538838 0.17590833 0.104975 0.213800 0.108825 0.926959477 0.006372943 FALSE TRUE
ENST00000396840 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding protein_coding 17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 0.2521449 0.0000000 0.7564347 0.0000000 0.7564347 6.26009092 0.01735833 0.000000 0.052075 0.052075 0.819860551 0.006372943 FALSE TRUE
ENST00000471408 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding retained_intron 17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 1.2622542 0.7853055 1.0840527 0.3302033 0.3962724 0.46010127 0.07468333 0.034500 0.074450 0.039950 0.774952544 0.006372943 FALSE TRUE
ENST00000619571 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding protein_coding 17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 0.4153362 1.2460087 0.0000000 1.2460087 0.0000000 -6.97270262 0.01864167 0.055925 0.000000 -0.055925 0.913327782 0.006372943 FALSE TRUE
MSTRG.5876.12 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding   17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 1.7264705 0.6066363 1.2120472 0.6066363 1.2120472 0.98680816 0.10286667 0.025800 0.078100 0.052300 0.970349247 0.006372943 FALSE TRUE
MSTRG.5876.14 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding   17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 1.8347431 1.3619068 1.3984679 1.3619068 0.8542426 0.03794427 0.11122500 0.067250 0.101525 0.034275 0.785498467 0.006372943 TRUE TRUE
MSTRG.5876.4 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding   17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 2.9267148 7.0661414 0.3965174 0.5268274 0.3965174 -4.12157381 0.13957500 0.314825 0.027075 -0.287750 0.006372943 0.006372943 TRUE TRUE
MSTRG.5876.8 ENSG00000010295 No_inf pgKDN_inf IFFO1 protein_coding   17.90735 22.45384 14.51151 0.8041437 0.4439255 -0.6294127 1.9178472 3.7783538 1.4649172 1.3193376 0.9386278 -1.36093712 0.09855000 0.162350 0.103200 -0.059150 0.829478471 0.006372943 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000010295 E001 0.0000000       12 6538961 6539527 567 -      
ENSG00000010295 E002 0.4992000 0.4475125983 1.000000000   12 6539528 6539534 7 - 0.130 0.181 0.567
ENSG00000010295 E003 0.6264624 0.1491815549 0.594786897 0.82176490 12 6539535 6539538 4 - 0.130 0.227 0.983
ENSG00000010295 E004 0.6264624 0.1491815549 0.594786897 0.82176490 12 6539539 6539540 2 - 0.130 0.227 0.983
ENSG00000010295 E005 2.0071495 0.0464686513 0.232350990 0.52102942 12 6539541 6539576 36 - 0.311 0.510 1.099
ENSG00000010295 E006 2.7693724 0.1443193681 0.099486024 0.32950622 12 6539577 6539606 30 - 0.311 0.630 1.646
ENSG00000010295 E007 100.3092675 0.0001914515 0.021732544 0.13377345 12 6539607 6540584 978 - 2.016 1.953 -0.210
ENSG00000010295 E008 7.0328052 0.0026290400 0.385285499 0.67134004 12 6540585 6540588 4 - 0.937 0.847 -0.347
ENSG00000010295 E009 23.9152165 0.0005970584 0.022910651 0.13807834 12 6541512 6541642 131 - 1.455 1.318 -0.475
ENSG00000010295 E010 23.2141764 0.0006781806 0.125486644 0.37548524 12 6548065 6548157 93 - 1.416 1.321 -0.328
ENSG00000010295 E011 9.4235388 0.0016896568 0.972707557 0.99491032 12 6548158 6548160 3 - 0.987 0.990 0.012
ENSG00000010295 E012 20.8177606 0.0006430206 0.036460237 0.18368690 12 6548161 6548424 264 - 1.203 1.349 0.511
ENSG00000010295 E013 24.4983530 0.0006639127 0.318627912 0.61126173 12 6548425 6548545 121 - 1.416 1.356 -0.209
ENSG00000010295 E014 23.3182971 0.0009710083 0.852599003 0.94794631 12 6548668 6548825 158 - 1.347 1.359 0.041
ENSG00000010295 E015 6.1297108 0.0022457584 0.049994602 0.22071644 12 6548826 6548849 24 - 0.651 0.887 0.947
ENSG00000010295 E016 31.7643466 0.0005706650 0.015262847 0.10640924 12 6548850 6549475 626 - 1.386 1.523 0.472
ENSG00000010295 E017 6.8101973 0.0026352664 0.608795183 0.82970535 12 6549476 6549484 9 - 0.901 0.847 -0.209
ENSG00000010295 E018 19.9455808 0.0007612668 0.767891438 0.91019776 12 6549756 6549896 141 - 1.304 1.284 -0.070
ENSG00000010295 E019 4.1482076 0.0806533692 0.034925487 0.17873690 12 6549897 6550467 571 - 0.882 0.554 -1.358
ENSG00000010295 E020 13.0963990 0.0011214664 0.061832993 0.24981168 12 6550695 6550790 96 - 1.002 1.164 0.587
ENSG00000010295 E021 9.9848703 0.0014266612 0.067681798 0.26255845 12 6550941 6551001 61 - 0.882 1.061 0.666
ENSG00000010295 E022 5.2841568 0.0041415593 0.001621926 0.02172262 12 6551398 6551503 106 - 0.438 0.867 1.871
ENSG00000010295 E023 2.1105019 0.0103050705 0.750830688 0.90169929 12 6551595 6551900 306 - 0.438 0.486 0.247
ENSG00000010295 E024 34.2480631 0.0025258158 0.873925952 0.95694492 12 6555257 6556073 817 - 1.510 1.519 0.031

Help

Please Click HERE to learn more details about the results from DEXseq.