ENSG00000011009

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374514 ENSG00000011009 No_inf pgKDN_inf LYPLA2 protein_coding protein_coding 55.1578 43.91199 60.9166 2.445585 2.963353 0.4721286 42.094793 37.148702 45.35905 0.9534268 1.455658 0.2880084 0.777100 0.85390 0.75015 -0.10375 0.50400161 0.03817155 FALSE TRUE
ENST00000421070 ENSG00000011009 No_inf pgKDN_inf LYPLA2 protein_coding protein_coding 55.1578 43.91199 60.9166 2.445585 2.963353 0.4721286 8.972403 2.501688 11.69878 2.5016878 1.892761 2.2208615 0.147975 0.04895 0.18905 0.14010 0.03817155 0.03817155 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011009 E001 3.8050240 0.0091263834 0.81764995 0.9336156 1 23791145 23791186 42 + 0.666 0.696 0.125
ENSG00000011009 E002 9.5630662 0.0014867543 0.75177268 0.9022075 1 23791187 23791202 16 + 1.008 1.037 0.106
ENSG00000011009 E003 17.6532980 0.0008572678 0.77043577 0.9115029 1 23791203 23791220 18 + 1.260 1.280 0.072
ENSG00000011009 E004 21.1889658 0.0006675516 0.95084887 0.9875356 1 23791221 23791250 30 + 1.344 1.348 0.016
ENSG00000011009 E005 0.1268540 0.0122976554 0.52734304   1 23791971 23791991 21 + 0.000 0.096 9.874
ENSG00000011009 E006 0.1268540 0.0122976554 0.52734304   1 23791992 23792017 26 + 0.000 0.096 9.874
ENSG00000011009 E007 0.5992382 0.0142638981 0.18007717 0.4554838 1 23792552 23792656 105 + 0.294 0.096 -1.968
ENSG00000011009 E008 42.2621038 0.0003580747 0.25851683 0.5508428 1 23792657 23792760 104 + 1.661 1.611 -0.168
ENSG00000011009 E009 25.7179788 0.0007340030 0.08443048 0.3000773 1 23793008 23793039 32 + 1.474 1.376 -0.339
ENSG00000011009 E010 30.6213615 0.0004953629 0.76648058 0.9093869 1 23793151 23793216 66 + 1.492 1.508 0.055
ENSG00000011009 E011 0.3522653 0.0249409165 0.10850753   1 23793653 23793704 52 + 0.237 0.000 -12.070
ENSG00000011009 E012 23.9951737 0.0006750596 0.88394371 0.9609687 1 23793705 23793752 48 + 1.393 1.402 0.032
ENSG00000011009 E013 34.9415571 0.0007500538 0.55212776 0.7957277 1 23793860 23793930 71 + 1.540 1.570 0.103
ENSG00000011009 E014 24.8329544 0.0017373712 0.16372139 0.4326512 1 23794063 23794091 29 + 1.367 1.451 0.290
ENSG00000011009 E015 28.7088966 0.0005417677 0.33847299 0.6302323 1 23794092 23794136 45 + 1.445 1.498 0.180
ENSG00000011009 E016 34.1877414 0.0004119629 0.62902912 0.8409693 1 23794224 23794325 102 + 1.534 1.558 0.084
ENSG00000011009 E017 2.5162941 0.1420970970 0.01358441 0.0981225 1 23794326 23794426 101 + 0.237 0.717 2.535
ENSG00000011009 E018 36.4420578 0.0041972357 0.71552395 0.8853259 1 23794427 23794551 125 + 1.583 1.564 -0.064
ENSG00000011009 E019 29.3852234 0.0017845416 0.87591695 0.9578256 1 23794552 23794600 49 + 1.478 1.487 0.032
ENSG00000011009 E020 2.4875591 0.1045769551 0.13564543 0.3914340 1 23794601 23794681 81 + 0.390 0.650 1.254
ENSG00000011009 E021 148.5812244 0.0002731083 0.23070449 0.5191645 1 23794682 23795539 858 + 2.187 2.162 -0.084

Help

Please Click HERE to learn more details about the results from DEXseq.