ENSG00000011021

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000346436 ENSG00000011021 No_inf pgKDN_inf CLCN6 protein_coding protein_coding 16.54527 22.45951 11.7422 2.304882 0.6380685 -0.9350381 9.8960415 9.594797 9.574558 0.5024845 0.6069811 -0.003043256 0.6686417 0.444350 0.81855 0.374200 0.007760869 0.007760869 FALSE TRUE
ENST00000446542 ENSG00000011021 No_inf pgKDN_inf CLCN6 protein_coding retained_intron 16.54527 22.45951 11.7422 2.304882 0.6380685 -0.9350381 0.3371103 1.011331 0.000000 0.3920141 0.0000000 -6.674306627 0.0173000 0.051900 0.00000 -0.051900 0.282203835 0.007760869 FALSE FALSE
ENST00000618496 ENSG00000011021 No_inf pgKDN_inf CLCN6 protein_coding misc_RNA 16.54527 22.45951 11.7422 2.304882 0.6380685 -0.9350381 2.8727258 5.708494 0.000000 3.3016904 0.0000000 -9.159491445 0.1170083 0.232825 0.00000 -0.232825 0.595276475 0.007760869   FALSE
ENST00000622391 ENSG00000011021 No_inf pgKDN_inf CLCN6 protein_coding misc_RNA 16.54527 22.45951 11.7422 2.304882 0.6380685 -0.9350381 0.9238726 2.771618 0.000000 2.7716177 0.0000000 -8.119780347 0.0373750 0.112125 0.00000 -0.112125 0.949511810 0.007760869   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011021 E001 0.0000000       1 11806096 11806190 95 +      
ENSG00000011021 E002 0.0000000       1 11806191 11806212 22 +      
ENSG00000011021 E003 0.0000000       1 11806213 11806230 18 +      
ENSG00000011021 E004 0.0000000       1 11806231 11806259 29 +      
ENSG00000011021 E005 0.0000000       1 11806260 11806262 3 +      
ENSG00000011021 E006 0.0000000       1 11806263 11806349 87 +      
ENSG00000011021 E007 1.2223651 0.0109157956 0.85287941 0.94811408 1 11807131 11807190 60 + 0.361 0.334 -0.165
ENSG00000011021 E008 2.7858506 0.0051132529 0.08285179 0.29659686 1 11815846 11815911 66 + 0.689 0.455 -1.072
ENSG00000011021 E009 3.1385187 0.1924610097 0.12195759 0.36949948 1 11816615 11816680 66 + 0.773 0.418 -1.608
ENSG00000011021 E010 3.0368768 0.2500368723 0.25779170 0.55003313 1 11819488 11819554 67 + 0.712 0.489 -0.996
ENSG00000011021 E011 0.9985567 0.0351827823 0.21173700 0.49677324 1 11820362 11820779 418 + 0.181 0.378 1.420
ENSG00000011021 E012 3.6192843 0.0038465963 0.01175201 0.08939813 1 11822695 11822801 107 + 0.809 0.489 -1.387
ENSG00000011021 E013 4.7390960 0.0279851404 0.18789075 0.46613154 1 11823707 11823833 127 + 0.843 0.672 -0.688
ENSG00000011021 E014 0.2459655 0.0169326553 0.92575213   1 11824367 11824485 119 + 0.100 0.090 -0.165
ENSG00000011021 E015 3.5154661 0.1498592204 0.33724563 0.62907987 1 11824486 11824553 68 + 0.753 0.549 -0.875
ENSG00000011021 E016 0.3719033 0.1783270882 0.69666705   1 11826137 11826155 19 + 0.100 0.165 0.835
ENSG00000011021 E017 3.7707790 0.0956776526 0.38837794 0.67422350 1 11826156 11826214 59 + 0.753 0.603 -0.634
ENSG00000011021 E018 0.3719033 0.1783270882 0.69666705   1 11826215 11826224 10 + 0.100 0.165 0.835
ENSG00000011021 E019 1.6915110 0.0599406899 0.24727574 0.53787427 1 11827089 11827114 26 + 0.523 0.334 -1.012
ENSG00000011021 E020 5.0461515 0.0150955805 0.50871889 0.76690944 1 11827115 11827221 107 + 0.733 0.816 0.333
ENSG00000011021 E021 5.7809519 0.0043795890 0.75466892 0.90351203 1 11828106 11828219 114 + 0.809 0.846 0.143
ENSG00000011021 E022 4.6181780 0.0042839773 0.10039744 0.33088385 1 11828458 11828624 167 + 0.843 0.650 -0.782
ENSG00000011021 E023 5.2865288 0.0586666609 0.98635613 0.99933518 1 11829196 11829322 127 + 0.791 0.801 0.037
ENSG00000011021 E024 2.6218025 0.0467325742 0.04796866 0.21550363 1 11829849 11830270 422 + 0.361 0.672 1.513
ENSG00000011021 E025 6.9435436 0.0020219832 0.10240995 0.33454743 1 11833515 11833638 124 + 0.980 0.816 -0.624
ENSG00000011021 E026 4.1283639 0.0036002504 0.08755663 0.30668133 1 11833877 11833886 10 + 0.809 0.603 -0.857
ENSG00000011021 E027 8.6451870 0.0223463088 0.19243155 0.47232198 1 11833887 11834030 144 + 1.055 0.912 -0.532
ENSG00000011021 E028 10.8177252 0.0013810598 0.60936195 0.83006183 1 11834236 11834395 160 + 1.046 1.091 0.164
ENSG00000011021 E029 7.6899842 0.0040368283 0.03894313 0.19105749 1 11834484 11834590 107 + 0.809 1.020 0.800
ENSG00000011021 E030 15.9177771 0.0021462474 0.39885859 0.68269302 1 11835967 11836153 187 + 1.258 1.199 -0.209
ENSG00000011021 E031 11.9604260 0.0017158412 0.25372682 0.54524020 1 11836999 11837156 158 + 1.056 1.152 0.346
ENSG00000011021 E032 10.0550760 0.0346167833 0.85088444 0.94721462 1 11837343 11837499 157 + 1.056 1.030 -0.095
ENSG00000011021 E033 6.4863667 0.0022751668 0.57256750 0.80844071 1 11838335 11838442 108 + 0.903 0.846 -0.219
ENSG00000011021 E034 5.8714133 0.0052589558 0.49318107 0.75516644 1 11838535 11838660 126 + 0.874 0.800 -0.285
ENSG00000011021 E035 0.6157612 0.0207481673 0.75346407 0.90301167 1 11838661 11839050 390 + 0.181 0.229 0.420
ENSG00000011021 E036 12.1934835 0.0163917043 0.42446415 0.70368701 1 11840143 11840371 229 + 1.075 1.152 0.276
ENSG00000011021 E037 45.3639388 0.0003545559 0.40679849 0.68940970 1 11840372 11841016 645 + 1.644 1.681 0.125
ENSG00000011021 E038 6.3753138 0.0024112500 0.88296442 0.96056242 1 11841017 11841057 41 + 0.874 0.860 -0.054
ENSG00000011021 E039 10.2040005 0.0023266796 0.65460915 0.85502494 1 11841058 11841207 150 + 1.025 1.066 0.149
ENSG00000011021 E040 112.0677774 0.0047602018 0.66914507 0.86233223 1 11841208 11842617 1410 + 2.044 2.058 0.047
ENSG00000011021 E041 42.1101630 0.0139596416 0.25409923 0.54572227 1 11842618 11843143 526 + 1.589 1.666 0.260
ENSG00000011021 E042 0.5082326 0.0913760838 0.06865106 0.26456780 1 11843704 11843733 30 + 0.000 0.284 12.486
ENSG00000011021 E043 0.8707287 0.1605924342 0.38702946 0.67293657 1 11843734 11843811 78 + 0.181 0.334 1.157
ENSG00000011021 E044 0.9981474 0.0125448994 0.20365667 0.48627673 1 11843812 11844073 262 + 0.181 0.378 1.420
ENSG00000011021 E045 0.1268540 0.0127793150 0.60480921   1 11845547 11845548 2 + 0.000 0.090 10.830
ENSG00000011021 E046 0.1268540 0.0127793150 0.60480921   1 11845549 11845766 218 + 0.000 0.090 10.830
ENSG00000011021 E047 0.0000000       1 11847434 11847441 8 +      
ENSG00000011021 E048 0.6259894 0.0159075201 0.21664541 0.50282096 1 11847442 11847576 135 + 0.100 0.284 1.835
ENSG00000011021 E049 1.6065068 0.0221725131 0.54823732 0.79338408 1 11847577 11848079 503 + 0.361 0.455 0.513

Help

Please Click HERE to learn more details about the results from DEXseq.