ENSG00000011028

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303375 ENSG00000011028 No_inf pgKDN_inf MRC2 protein_coding protein_coding 96.68982 166.6109 59.86548 1.40732 1.160106 -1.476532 45.12245 65.14649 37.412000 0.4808009 1.010423 -0.8000222 0.5110083 0.391075 0.624975 0.233900 7.774032e-08 7.774032e-08 FALSE TRUE
ENST00000583597 ENSG00000011028 No_inf pgKDN_inf MRC2 protein_coding retained_intron 96.68982 166.6109 59.86548 1.40732 1.160106 -1.476532 21.86365 39.99563 12.168583 0.8527471 1.462739 -1.7158568 0.2180333 0.240000 0.204125 -0.035875 8.179193e-01 7.774032e-08 FALSE TRUE
MSTRG.13087.9 ENSG00000011028 No_inf pgKDN_inf MRC2 protein_coding   96.68982 166.6109 59.86548 1.40732 1.160106 -1.476532 23.21738 48.58485 7.689699 1.6573515 1.445199 -2.6579294 0.2097583 0.291425 0.127600 -0.163825 1.815002e-03 7.774032e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011028 E001 2.2307683 6.119072e-03 5.938738e-01 8.211555e-01 17 62627670 62627682 13 + 0.530 0.448 -0.399
ENSG00000011028 E002 2.2307683 6.119072e-03 5.938738e-01 8.211555e-01 17 62627683 62627684 2 + 0.530 0.448 -0.399
ENSG00000011028 E003 38.8101684 1.043001e-03 2.734818e-04 5.391070e-03 17 62627685 62627920 236 + 1.677 1.487 -0.648
ENSG00000011028 E004 97.1043783 1.684216e-04 1.129910e-03 1.645825e-02 17 62664548 62664949 402 + 2.014 1.905 -0.366
ENSG00000011028 E005 65.5621560 2.341401e-04 9.171302e-02 3.144796e-01 17 62666094 62666267 174 + 1.818 1.748 -0.236
ENSG00000011028 E006 53.4717899 4.845697e-04 4.326941e-02 2.028473e-01 17 62666455 62666619 165 + 1.747 1.655 -0.313
ENSG00000011028 E007 48.3606667 3.152630e-03 2.480679e-02 1.447975e-01 17 62666757 62666870 114 + 1.722 1.604 -0.399
ENSG00000011028 E008 65.3821313 8.004491e-03 5.661212e-03 5.414644e-02 17 62667390 62667533 144 + 1.873 1.722 -0.509
ENSG00000011028 E009 82.6358871 2.094612e-04 1.163986e-02 8.882066e-02 17 62671649 62671837 189 + 1.933 1.841 -0.311
ENSG00000011028 E010 74.4775211 1.351715e-03 4.523688e-02 2.079138e-01 17 62671998 62672152 155 + 1.882 1.799 -0.279
ENSG00000011028 E011 57.1614334 2.689445e-04 1.071457e-02 8.404296e-02 17 62674063 62674170 108 + 1.788 1.677 -0.376
ENSG00000011028 E012 49.5124008 2.896009e-04 8.034589e-04 1.265147e-02 17 62675790 62675905 116 + 1.756 1.602 -0.522
ENSG00000011028 E013 23.1249263 5.986928e-04 5.823735e-03 5.523076e-02 17 62676383 62676393 11 + 1.454 1.274 -0.625
ENSG00000011028 E014 48.9603463 6.382375e-04 1.135915e-04 2.636164e-03 17 62676394 62676531 138 + 1.768 1.589 -0.608
ENSG00000011028 E015 0.6264628 1.414313e-02 7.364816e-01 8.954328e-01 17 62676532 62676604 73 + 0.145 0.205 0.600
ENSG00000011028 E016 66.4434234 1.227109e-03 1.187249e-04 2.737628e-03 17 62677269 62677486 218 + 1.886 1.725 -0.542
ENSG00000011028 E017 36.9173668 3.869826e-04 1.696046e-02 1.137036e-01 17 62678504 62678617 114 + 1.614 1.487 -0.435
ENSG00000011028 E018 7.6683951 2.857523e-02 2.281299e-01 5.166039e-01 17 62678618 62678646 29 + 0.989 0.847 -0.537
ENSG00000011028 E019 0.0000000       17 62679800 62679902 103 +      
ENSG00000011028 E020 0.0000000       17 62680170 62680308 139 +      
ENSG00000011028 E021 0.0000000       17 62680418 62680453 36 +      
ENSG00000011028 E022 0.0000000       17 62680631 62680799 169 +      
ENSG00000011028 E023 0.0000000       17 62680800 62680960 161 +      
ENSG00000011028 E024 0.0000000       17 62681062 62681129 68 +      
ENSG00000011028 E025 0.8810824 2.174392e-02 4.221836e-01 7.014587e-01 17 62681453 62681457 5 + 0.145 0.280 1.185
ENSG00000011028 E026 6.5059920 6.130267e-03 3.024561e-01 5.955268e-01 17 62681458 62681836 379 + 0.730 0.856 0.499
ENSG00000011028 E027 47.0814168 5.548311e-03 6.935492e-01 8.748199e-01 17 62681837 62681937 101 + 1.610 1.632 0.076
ENSG00000011028 E028 4.1543092 2.872372e-02 4.702191e-02 2.129959e-01 17 62682056 62682234 179 + 0.413 0.730 1.459
ENSG00000011028 E029 88.4980229 2.156889e-04 2.167133e-01 5.028271e-01 17 62682235 62682377 143 + 1.863 1.907 0.148
ENSG00000011028 E030 91.8986801 1.585090e-04 4.384000e-01 7.146163e-01 17 62688289 62688403 115 + 1.933 1.905 -0.095
ENSG00000011028 E031 121.3240935 1.967105e-03 4.287255e-02 2.018408e-01 17 62688501 62688664 164 + 2.083 2.012 -0.239
ENSG00000011028 E032 5.6387596 6.741386e-03 1.355729e-01 3.913034e-01 17 62688691 62688851 161 + 0.621 0.818 0.810
ENSG00000011028 E033 39.2199686 1.017736e-03 1.475903e-01 4.090089e-01 17 62688852 62688857 6 + 1.606 1.528 -0.267
ENSG00000011028 E034 41.3740450 7.545388e-04 3.237955e-01 6.163909e-01 17 62688858 62688877 20 + 1.610 1.558 -0.179
ENSG00000011028 E035 75.4751831 2.439742e-04 7.193393e-01 8.868075e-01 17 62688878 62688960 83 + 1.818 1.831 0.043
ENSG00000011028 E036 10.3124503 9.132378e-03 3.696574e-03 4.021290e-02 17 62688961 62689370 410 + 0.730 1.068 1.291
ENSG00000011028 E037 4.3886987 3.232998e-03 1.519649e-01 4.156435e-01 17 62689371 62689437 67 + 0.530 0.730 0.874
ENSG00000011028 E038 4.7847703 5.826116e-02 2.971527e-02 1.621005e-01 17 62689438 62689521 84 + 0.413 0.787 1.688
ENSG00000011028 E039 122.3043071 1.397713e-04 7.626064e-01 9.073746e-01 17 62689522 62689760 239 + 2.043 2.032 -0.035
ENSG00000011028 E040 4.5258362 3.539901e-03 5.175279e-02 2.258098e-01 17 62689761 62689893 133 + 0.475 0.754 1.233
ENSG00000011028 E041 108.7264868 2.596159e-04 6.393334e-01 8.466348e-01 17 62689894 62690062 169 + 1.996 1.980 -0.055
ENSG00000011028 E042 132.5959586 1.791892e-04 3.606124e-01 6.502597e-01 17 62690156 62690305 150 + 2.090 2.062 -0.093
ENSG00000011028 E043 157.5021207 2.305509e-04 2.487675e-01 5.396383e-01 17 62690642 62690761 120 + 2.121 2.152 0.102
ENSG00000011028 E044 190.6103411 1.583647e-04 3.617126e-04 6.776175e-03 17 62690949 62691128 180 + 2.159 2.248 0.297
ENSG00000011028 E045 1.7275225 9.139556e-01 9.696992e-01 9.937648e-01 17 62691949 62691975 27 + 0.474 0.372 -0.545
ENSG00000011028 E046 69.1838702 2.405835e-04 1.314209e-02 9.603734e-02 17 62692112 62692138 27 + 1.712 1.815 0.350
ENSG00000011028 E047 356.9126175 8.606764e-05 7.439070e-09 5.414559e-07 17 62692231 62692726 496 + 2.419 2.522 0.345
ENSG00000011028 E048 548.4831637 1.473563e-04 6.027125e-12 7.128661e-10 17 62692727 62693597 871 + 2.609 2.707 0.328

Help

Please Click HERE to learn more details about the results from DEXseq.