ENSG00000011114

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000298896 ENSG00000011114 No_inf pgKDN_inf BTBD7 protein_coding protein_coding 10.49888 11.03092 10.29352 0.9871908 0.3388024 -0.09972366 1.7240789 1.7399964 0.9205312 0.4671135 0.4212698 -0.9112256 0.17000000 0.170575 0.093000 -0.077575 0.80302090 0.01962144 FALSE TRUE
ENST00000334746 ENSG00000011114 No_inf pgKDN_inf BTBD7 protein_coding protein_coding 10.49888 11.03092 10.29352 0.9871908 0.3388024 -0.09972366 1.6930639 0.2879008 3.1615983 0.2879008 0.3751846 3.4123063 0.16527500 0.028125 0.310150 0.282025 0.01962144 0.01962144 FALSE TRUE
ENST00000355125 ENSG00000011114 No_inf pgKDN_inf BTBD7 protein_coding nonsense_mediated_decay 10.49888 11.03092 10.29352 0.9871908 0.3388024 -0.09972366 1.3744010 1.4952958 0.2945362 0.5024675 0.2945362 -2.3053614 0.13701667 0.148625 0.028250 -0.120375 0.44679536 0.01962144 FALSE TRUE
ENST00000555525 ENSG00000011114 No_inf pgKDN_inf BTBD7 protein_coding protein_coding 10.49888 11.03092 10.29352 0.9871908 0.3388024 -0.09972366 0.8102235 1.1143478 1.3163227 0.7386847 0.5499805 0.2383435 0.07101667 0.088525 0.124525 0.036000 0.84609057 0.01962144 FALSE TRUE
MSTRG.9003.1 ENSG00000011114 No_inf pgKDN_inf BTBD7 protein_coding   10.49888 11.03092 10.29352 0.9871908 0.3388024 -0.09972366 4.1353302 5.1894062 4.0208527 0.7257744 0.3259283 -0.3672618 0.38894167 0.465450 0.388775 -0.076675 0.83262275 0.01962144   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011114 E001 176.2158276 0.0001421927 0.03516495 0.17948202 14 93237550 93242032 4483 - 2.234 2.260 0.087
ENSG00000011114 E002 2.1980994 0.0330565285 0.65772456 0.85687375 14 93242033 93242037 5 - 0.538 0.470 -0.330
ENSG00000011114 E003 12.7133942 0.0552152288 0.71796332 0.88650726 14 93242038 93242435 398 - 1.169 1.105 -0.231
ENSG00000011114 E004 15.3355367 0.0268198814 0.15267203 0.41683777 14 93242436 93243088 653 - 1.277 1.144 -0.469
ENSG00000011114 E005 2.2220809 0.0092643512 0.35020427 0.64044205 14 93245825 93245863 39 - 0.434 0.566 0.645
ENSG00000011114 E006 8.6970934 0.0016769633 0.92071653 0.97521456 14 93245864 93246286 423 - 0.993 0.980 -0.048
ENSG00000011114 E007 5.0632314 0.0032524786 0.15626116 0.42254285 14 93248476 93248654 179 - 0.693 0.851 0.636
ENSG00000011114 E008 3.4235414 0.0410870432 0.78600574 0.91754542 14 93251463 93251652 190 - 0.670 0.620 -0.215
ENSG00000011114 E009 2.8305711 0.0057087883 0.52918232 0.78057432 14 93253647 93253790 144 - 0.538 0.621 0.371
ENSG00000011114 E010 2.7307579 0.0065987922 0.08649577 0.30476664 14 93255510 93257194 1685 - 0.434 0.669 1.092
ENSG00000011114 E011 3.2451246 0.1294505724 0.05922826 0.24425883 14 93257195 93257355 161 - 0.771 0.433 -1.520
ENSG00000011114 E012 2.0498501 0.0068741137 0.08990080 0.31146369 14 93261602 93261677 76 - 0.596 0.346 -1.271
ENSG00000011114 E013 5.0808474 0.0027618345 0.03109854 0.16619978 14 93263785 93263993 209 - 0.896 0.645 -1.008
ENSG00000011114 E014 0.3811266 0.0231599759 0.10310493   14 93287628 93287671 44 - 0.000 0.239 11.475
ENSG00000011114 E015 17.2711443 0.0008397524 0.01442364 0.10234502 14 93287672 93288707 1036 - 1.169 1.333 0.577
ENSG00000011114 E016 0.4985061 0.0477719956 0.32155026   14 93288708 93288730 23 - 0.095 0.239 1.577
ENSG00000011114 E017 18.8420308 0.0008295390 0.01196617 0.09030129 14 93293858 93294630 773 - 1.377 1.208 -0.593
ENSG00000011114 E018 5.8187794 0.0028810396 0.08678483 0.30536618 14 93294631 93294852 222 - 0.922 0.732 -0.745
ENSG00000011114 E019 1.7257454 0.0080190086 0.59022136 0.81864470 14 93294853 93294937 85 - 0.393 0.470 0.407
ENSG00000011114 E020 2.5500436 0.0905516960 0.41691924 0.69671422 14 93295970 93296157 188 - 0.622 0.470 -0.708
ENSG00000011114 E021 0.1170040 0.0117713339 0.54179657   14 93296158 93296158 1 - 0.095 0.000 -11.015
ENSG00000011114 E022 0.0000000       14 93332304 93332346 43 -      
ENSG00000011114 E023 1.7330175 0.0077130506 0.28304123 0.57670254 14 93332820 93333092 273 - 0.348 0.505 0.840

Help

Please Click HERE to learn more details about the results from DEXseq.