ENSG00000011304

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000349038 ENSG00000011304 No_inf pgKDN_inf PTBP1 protein_coding protein_coding 107.9086 84.14521 112.8359 1.963458 3.077312 0.4232301 34.306090 15.580817 36.637152 5.5520344 3.0583397 1.2330046 0.30550833 0.187075 0.324800 0.137725 0.68480637 0.00213017 FALSE  
ENST00000356948 ENSG00000011304 No_inf pgKDN_inf PTBP1 protein_coding protein_coding 107.9086 84.14521 112.8359 1.963458 3.077312 0.4232301 37.662458 29.623202 45.245410 3.5332402 3.8666097 0.6108757 0.35259167 0.353700 0.401550 0.047850 0.83472787 0.00213017 FALSE  
ENST00000585856 ENSG00000011304 No_inf pgKDN_inf PTBP1 protein_coding retained_intron 107.9086 84.14521 112.8359 1.963458 3.077312 0.4232301 3.777282 5.740872 1.613226 0.1443159 0.1304745 -1.8249167 0.03863333 0.068250 0.014375 -0.053875 0.00213017 0.00213017 FALSE  
ENST00000679114 ENSG00000011304 No_inf pgKDN_inf PTBP1 protein_coding protein_coding 107.9086 84.14521 112.8359 1.963458 3.077312 0.4232301 9.959099 8.015828 12.174665 2.9738005 3.4852877 0.6023444 0.09485000 0.094250 0.105850 0.011600 0.92104847 0.00213017 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011304 E001 0.1187032 0.0118499981 6.813684e-01   19 797075 797391 317 + 0.085 0.000 -8.848
ENSG00000011304 E002 0.2357071 0.0157084837 3.351409e-01   19 797392 797397 6 + 0.157 0.000 -12.095
ENSG00000011304 E003 0.5965691 0.2095674385 3.445499e-01 6.357429e-01 19 797398 797424 27 + 0.272 0.106 -1.657
ENSG00000011304 E004 1.5750165 0.2292450941 8.984876e-01 9.666287e-01 19 797425 797426 2 + 0.437 0.376 -0.334
ENSG00000011304 E005 1.5750165 0.2292450941 8.984876e-01 9.666287e-01 19 797427 797427 1 + 0.437 0.376 -0.334
ENSG00000011304 E006 4.1138686 0.1150295654 4.654826e-01 7.344823e-01 19 797428 797451 24 + 0.762 0.634 -0.531
ENSG00000011304 E007 8.1237553 0.0317977386 3.613122e-01 6.508101e-01 19 797452 797461 10 + 1.006 0.897 -0.406
ENSG00000011304 E008 24.6667667 0.0047708640 4.595290e-03 4.666672e-02 19 797462 797489 28 + 1.485 1.295 -0.658
ENSG00000011304 E009 30.0800753 0.0215508463 1.191892e-01 3.648257e-01 19 797490 797505 16 + 1.543 1.421 -0.420
ENSG00000011304 E010 0.6344230 0.1807603919 2.121300e-02 1.317354e-01 19 798428 798545 118 + 0.000 0.376 12.261
ENSG00000011304 E011 0.3639133 0.2384790535 7.894332e-01   19 799406 799412 7 + 0.157 0.106 -0.660
ENSG00000011304 E012 35.8217082 0.0063871299 1.143763e-01 3.563293e-01 19 799413 799443 31 + 1.606 1.511 -0.325
ENSG00000011304 E013 3.1254747 0.0103108509 3.431024e-04 6.486114e-03 19 799444 800081 638 + 0.320 0.814 2.341
ENSG00000011304 E014 36.8848333 0.0056914836 3.778298e-02 1.875796e-01 19 803561 803574 14 + 1.629 1.507 -0.416
ENSG00000011304 E015 27.3130009 0.0110902380 1.234036e-01 3.719070e-01 19 803575 803576 2 + 1.498 1.388 -0.378
ENSG00000011304 E016 45.0623759 0.0115146095 1.085461e-01 3.456938e-01 19 803577 803636 60 + 1.706 1.603 -0.348
ENSG00000011304 E017 92.1432058 0.0001740725 1.493302e-02 1.047464e-01 19 804036 804208 173 + 2.002 1.924 -0.261
ENSG00000011304 E018 1.4891334 0.0168078987 1.235672e-01 3.722222e-01 19 804209 804291 83 + 0.272 0.506 1.341
ENSG00000011304 E019 60.6672197 0.0002865639 1.076772e-01 3.440559e-01 19 804292 804388 97 + 1.817 1.753 -0.215
ENSG00000011304 E020 47.3195627 0.0061073124 3.866887e-01 6.725460e-01 19 804389 804438 50 + 1.704 1.657 -0.160
ENSG00000011304 E021 1.3622144 0.0096886520 1.976142e-01 4.789092e-01 19 804439 804531 93 + 0.272 0.467 1.149
ENSG00000011304 E022 26.3972300 0.0019654709 4.628076e-01 7.329899e-01 19 804532 804540 9 + 1.457 1.412 -0.155
ENSG00000011304 E023 65.9991530 0.0041430258 1.320537e-01 3.855873e-01 19 804541 804622 82 + 1.855 1.786 -0.235
ENSG00000011304 E024 72.5074309 0.0004807800 1.807935e-02 1.186243e-01 19 804623 804702 80 + 1.903 1.816 -0.292
ENSG00000011304 E025 41.5175283 0.0011443692 5.088395e-01 7.669783e-01 19 804829 804857 29 + 1.642 1.609 -0.111
ENSG00000011304 E026 64.5599775 0.0024685787 5.359798e-01 7.853601e-01 19 804858 804939 82 + 1.804 1.829 0.084
ENSG00000011304 E027 0.0000000       19 804940 805012 73 +      
ENSG00000011304 E028 74.6243601 0.0011367224 9.596558e-01 9.905852e-01 19 805013 805095 83 + 1.878 1.876 -0.009
ENSG00000011304 E029 72.3549881 0.0006402414 5.144217e-02 2.248182e-01 19 805096 805187 92 + 1.896 1.823 -0.244
ENSG00000011304 E030 5.8430181 0.0077184811 5.129974e-04 8.919407e-03 19 805188 805491 304 + 0.607 1.004 1.579
ENSG00000011304 E031 22.7282728 0.0006299182 2.192993e-01 5.059770e-01 19 805492 805507 16 + 1.408 1.330 -0.269
ENSG00000011304 E032 23.4995920 0.0005932764 5.622184e-01 8.021238e-01 19 805508 805512 5 + 1.404 1.368 -0.126
ENSG00000011304 E033 34.4846650 0.0003900522 7.496395e-01 9.013656e-01 19 805513 805569 57 + 1.556 1.539 -0.059
ENSG00000011304 E034 5.6377162 0.0198266857 1.601762e-06 7.012129e-05 19 805570 805831 262 + 0.438 1.049 2.551
ENSG00000011304 E035 2.6045070 0.0059515222 3.992725e-02 1.936892e-01 19 805832 805902 71 + 0.402 0.686 1.341
ENSG00000011304 E036 10.4417827 0.0200024377 4.432280e-05 1.207936e-03 19 805903 806407 505 + 0.809 1.237 1.580
ENSG00000011304 E037 86.5024835 0.0002934849 4.602917e-01 7.317506e-01 19 806408 806556 149 + 1.952 1.927 -0.084
ENSG00000011304 E038 39.3263448 0.0003710538 2.716048e-24 1.053866e-21 19 806557 807858 1302 + 1.299 1.807 1.738
ENSG00000011304 E039 4.8603248 0.0029245409 1.488797e-04 3.282779e-03 19 807859 807868 10 + 0.502 0.954 1.878
ENSG00000011304 E040 49.5142274 0.0003092076 9.892476e-01 1.000000e+00 19 807869 807902 34 + 1.702 1.702 -0.001
ENSG00000011304 E041 9.7054523 0.0014523916 9.662781e-07 4.523893e-05 19 807903 808359 457 + 0.762 1.216 1.689
ENSG00000011304 E042 42.6276478 0.0021230576 4.700972e-01 7.380164e-01 19 808360 808379 20 + 1.655 1.618 -0.124
ENSG00000011304 E043 75.6547207 0.0003402374 8.178848e-01 9.337017e-01 19 808380 808452 73 + 1.880 1.887 0.024
ENSG00000011304 E044 93.1019425 0.0031142927 7.752678e-01 9.136830e-01 19 808546 808649 104 + 1.967 1.978 0.034
ENSG00000011304 E045 103.9423666 0.0001619851 5.401814e-01 7.883036e-01 19 808650 808762 113 + 2.028 2.009 -0.064
ENSG00000011304 E046 78.5862162 0.0002911031 7.954952e-01 9.223427e-01 19 810543 810620 78 + 1.896 1.903 0.027
ENSG00000011304 E047 760.3302041 0.0001277769 4.316872e-03 4.474432e-02 19 810694 812327 1634 + 2.868 2.894 0.088

Help

Please Click HERE to learn more details about the results from DEXseq.