ENSG00000011426

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265748 ENSG00000011426 No_inf pgKDN_inf ANLN protein_coding protein_coding 16.65809 13.99039 19.28798 0.9574507 1.177165 0.4629825 6.281519 3.309492 9.066661 2.4183398 1.7387240 1.4511992 0.37203333 0.247075 0.474175 0.227100 0.50207416 0.03591972 FALSE TRUE
ENST00000396068 ENSG00000011426 No_inf pgKDN_inf ANLN protein_coding protein_coding 16.65809 13.99039 19.28798 0.9574507 1.177165 0.4629825 4.352622 2.555598 5.870780 1.4478800 0.9725048 1.1967121 0.25847500 0.192175 0.308150 0.115975 0.66944328 0.03591972 FALSE TRUE
ENST00000491782 ENSG00000011426 No_inf pgKDN_inf ANLN protein_coding retained_intron 16.65809 13.99039 19.28798 0.9574507 1.177165 0.4629825 1.071182 2.526238 0.443856 0.5952008 0.2002781 -2.4823835 0.07321667 0.182925 0.022050 -0.160875 0.03591972 0.03591972   FALSE
MSTRG.26063.3 ENSG00000011426 No_inf pgKDN_inf ANLN protein_coding   16.65809 13.99039 19.28798 0.9574507 1.177165 0.4629825 3.675297 3.748932 2.086723 2.1644661 1.2096895 -0.8421868 0.22427500 0.256275 0.110275 -0.146000 0.94522536 0.03591972 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011426 E001 0.1186381 0.0118132815 0.7806375662   7 36389821 36389824 4 + 0.081 0.000 -8.377
ENSG00000011426 E002 0.2451451 0.0164238956 0.7754940153   7 36389825 36389827 3 + 0.081 0.112 0.525
ENSG00000011426 E003 1.0970802 0.0151902310 0.8337364325 0.94012616 7 36389828 36389861 34 + 0.305 0.337 0.203
ENSG00000011426 E004 2.4186419 0.0073398622 0.5917023929 0.81956077 7 36389862 36390044 183 + 0.563 0.485 -0.368
ENSG00000011426 E005 0.0000000       7 36390171 36390211 41 +      
ENSG00000011426 E006 0.0000000       7 36390235 36390541 307 +      
ENSG00000011426 E007 6.6776884 0.0022922031 0.6790577589 0.86731952 7 36396266 36396419 154 + 0.900 0.855 -0.170
ENSG00000011426 E008 0.1170040 0.0117194352 0.7805904402   7 36396420 36396421 2 + 0.081 0.000 -10.934
ENSG00000011426 E009 15.5089182 0.0010428535 0.1790695279 0.45413877 7 36399079 36399393 315 + 1.254 1.153 -0.358
ENSG00000011426 E010 0.0000000       7 36403493 36403566 74 +      
ENSG00000011426 E011 11.5346132 0.0011721628 0.5442507354 0.79075877 7 36406181 36406401 221 + 1.115 1.063 -0.188
ENSG00000011426 E012 3.0240163 0.0053020132 0.3611490805 0.65074731 7 36406402 36406402 1 + 0.650 0.525 -0.562
ENSG00000011426 E013 8.5801084 0.0016985527 0.0842562305 0.29974214 7 36406403 36406532 130 + 1.041 0.873 -0.630
ENSG00000011426 E014 4.2336903 0.0041380100 0.4251343092 0.70419605 7 36406533 36406550 18 + 0.755 0.655 -0.413
ENSG00000011426 E015 4.1329269 0.0131325454 0.9743482771 0.99538773 7 36406551 36406566 16 + 0.706 0.708 0.011
ENSG00000011426 E016 0.0000000       7 36406567 36406570 4 +      
ENSG00000011426 E017 0.0000000       7 36407718 36407733 16 +      
ENSG00000011426 E018 13.7182501 0.0021127671 0.5392223535 0.78771430 7 36407734 36407956 223 + 1.184 1.134 -0.178
ENSG00000011426 E019 8.0079657 0.0018392956 0.6131853602 0.83181039 7 36410514 36410559 46 + 0.972 0.921 -0.189
ENSG00000011426 E020 12.3838362 0.0011751548 0.5773820705 0.81114127 7 36410560 36410655 96 + 1.142 1.095 -0.167
ENSG00000011426 E021 7.2676192 0.0018996762 0.3481698541 0.63864888 7 36410656 36410704 49 + 0.952 0.855 -0.368
ENSG00000011426 E022 11.5006478 0.0319470316 0.3607001658 0.65037452 7 36411059 36411166 108 + 1.135 1.029 -0.384
ENSG00000011426 E023 13.6485542 0.0011423685 0.5469541623 0.79256206 7 36415758 36415884 127 + 1.142 1.187 0.163
ENSG00000011426 E024 0.0000000       7 36415885 36415885 1 +      
ENSG00000011426 E025 9.8188964 0.0036232172 0.2490042014 0.53985378 7 36417080 36417190 111 + 1.072 0.965 -0.396
ENSG00000011426 E026 18.1053080 0.0008130566 0.6139589217 0.83218483 7 36419244 36419467 224 + 1.292 1.256 -0.125
ENSG00000011426 E027 3.9922982 0.0053258302 0.3757140482 0.66309723 7 36419468 36419479 12 + 0.739 0.626 -0.475
ENSG00000011426 E028 7.0244228 0.0019584146 0.3155066440 0.60836350 7 36420169 36420223 55 + 0.942 0.837 -0.401
ENSG00000011426 E029 11.6462552 0.0012123239 0.4926057623 0.75471449 7 36420224 36420314 91 + 1.122 1.063 -0.212
ENSG00000011426 E030 5.8246235 0.0028970345 0.6305982512 0.84149963 7 36420597 36420611 15 + 0.853 0.798 -0.212
ENSG00000011426 E031 13.8128306 0.0010290808 0.2766065698 0.57010900 7 36420612 36420744 133 + 1.201 1.115 -0.307
ENSG00000011426 E032 13.5002560 0.0095042614 0.9319029819 0.98015280 7 36421857 36421992 136 + 1.160 1.153 -0.027
ENSG00000011426 E033 14.5625942 0.0418918957 0.4361251939 0.71255728 7 36422633 36422722 90 + 1.223 1.134 -0.316
ENSG00000011426 E034 13.1882619 0.0012021640 0.0893106493 0.31024607 7 36422723 36422809 87 + 1.201 1.063 -0.495
ENSG00000011426 E035 13.2453769 0.0020184321 0.7527150071 0.90263025 7 36423817 36423943 127 + 1.160 1.134 -0.093
ENSG00000011426 E036 8.4507240 0.0018390296 0.1037698476 0.33670575 7 36424545 36424593 49 + 0.900 1.052 0.567
ENSG00000011426 E037 9.7566644 0.0015731096 0.4643713945 0.73388832 7 36424686 36424742 57 + 0.999 1.063 0.236
ENSG00000011426 E038 11.1378548 0.0025717721 0.0683291012 0.26383604 7 36425702 36425740 39 + 1.008 1.162 0.557
ENSG00000011426 E039 9.2916724 0.0015766687 0.1745083425 0.44827267 7 36426015 36426036 22 + 0.952 1.074 0.449
ENSG00000011426 E040 13.9624291 0.0046172992 0.7083101920 0.88176951 7 36426916 36427028 113 + 1.184 1.153 -0.112
ENSG00000011426 E041 0.4793989 0.4506035580 0.7627297639   7 36428307 36428360 54 + 0.207 0.112 -1.059
ENSG00000011426 E042 8.9131808 0.0400124367 0.5479445261 0.79323706 7 36439204 36439290 87 + 0.962 1.029 0.248
ENSG00000011426 E043 13.1687876 0.0030432944 0.4704197613 0.73812109 7 36443755 36443862 108 + 1.122 1.179 0.203
ENSG00000011426 E044 1.9967931 0.0079250670 0.0062977297 0.05841131 7 36448939 36449664 726 + 0.259 0.655 2.110
ENSG00000011426 E045 24.0903979 0.0033920491 0.9803807684 0.99781716 7 36449665 36449837 173 + 1.396 1.394 -0.005
ENSG00000011426 E046 123.7702725 0.0003071335 0.0007254061 0.01166142 7 36452477 36453791 1315 + 2.055 2.136 0.268

Help

Please Click HERE to learn more details about the results from DEXseq.