ENSG00000011485

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000012443 ENSG00000011485 No_inf pgKDN_inf PPP5C protein_coding protein_coding 43.21377 44.54862 37.54054 2.140555 5.086808 -0.246871 27.280017 20.812389 30.372020 1.2685121 0.1614425 0.5450822 0.65219167 0.466875 0.844575 0.377700 0.002174815 0.002174815 FALSE TRUE
ENST00000467902 ENSG00000011485 No_inf pgKDN_inf PPP5C protein_coding retained_intron 43.21377 44.54862 37.54054 2.140555 5.086808 -0.246871 1.226117 2.815343 0.000000 1.1351372 0.0000000 -8.1422823 0.02752500 0.064225 0.000000 -0.064225 0.058010150 0.002174815 FALSE FALSE
ENST00000493347 ENSG00000011485 No_inf pgKDN_inf PPP5C protein_coding retained_intron 43.21377 44.54862 37.54054 2.140555 5.086808 -0.246871 8.464095 10.002341 4.355358 1.5390923 4.3553582 -1.1976074 0.17862500 0.221550 0.082500 -0.139050 0.057950856 0.002174815   FALSE
ENST00000595055 ENSG00000011485 No_inf pgKDN_inf PPP5C protein_coding retained_intron 43.21377 44.54862 37.54054 2.140555 5.086808 -0.246871 1.695470 3.544173 0.602012 0.9166082 0.3543173 -2.5378823 0.03813333 0.079175 0.015375 -0.063800 0.190961443 0.002174815   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000011485 E001 7.2290430 0.0020642710 7.521508e-01 0.9024169162 19 46347087 46347100 14 + 0.892 0.938 0.177
ENSG00000011485 E002 8.4272402 0.0016720972 6.920105e-01 0.8739291817 19 46347101 46347107 7 + 0.985 0.963 -0.082
ENSG00000011485 E003 21.7660657 0.0011031564 4.662186e-02 0.2118725554 19 46347108 46347217 110 + 1.408 1.300 -0.377
ENSG00000011485 E004 37.5306443 0.0003953562 5.023947e-04 0.0087838156 19 46353748 46353989 242 + 1.653 1.505 -0.508
ENSG00000011485 E005 12.9896989 0.0010741927 2.978773e-02 0.1623291242 19 46375604 46375626 23 + 1.216 1.060 -0.559
ENSG00000011485 E006 31.1195120 0.0004425143 2.856065e-01 0.5792028182 19 46375627 46375751 125 + 1.526 1.487 -0.133
ENSG00000011485 E007 33.8392516 0.0004858462 5.315122e-01 0.7821388364 19 46376453 46376574 122 + 1.549 1.535 -0.050
ENSG00000011485 E008 1.1409887 0.0178715101 8.597895e-04 0.0133482697 19 46376575 46376703 129 + 0.000 0.519 14.667
ENSG00000011485 E009 1.7591392 0.0784800827 9.499134e-03 0.0777902081 19 46381511 46381725 215 + 0.167 0.610 2.713
ENSG00000011485 E010 9.5935787 0.0390931868 1.178649e-03 0.0169653694 19 46381726 46382771 1046 + 0.772 1.186 1.543
ENSG00000011485 E011 0.0000000       19 46382772 46383155 384 +      
ENSG00000011485 E012 1.5256055 0.3461417272 9.847500e-03 0.0794725496 19 46383156 46383322 167 + 0.000 0.610 15.083
ENSG00000011485 E013 1.6515478 0.0642207080 1.395316e-04 0.0031208963 19 46383323 46383410 88 + 0.000 0.636 15.198
ENSG00000011485 E014 17.3518402 0.0009438475 7.057085e-01 0.8804868051 19 46383411 46383462 52 + 1.269 1.259 -0.035
ENSG00000011485 E015 13.7858506 0.0010256701 4.395889e-01 0.7155503273 19 46383463 46383476 14 + 1.191 1.148 -0.154
ENSG00000011485 E016 4.8956704 0.0029069552 3.374294e-06 0.0001336191 19 46383477 46383779 303 + 0.381 0.975 2.587
ENSG00000011485 E017 11.3516382 0.0036104799 6.409087e-01 0.8475986962 19 46383780 46383783 4 + 1.104 1.079 -0.090
ENSG00000011485 E018 15.0173604 0.0134100371 8.109901e-01 0.9304532019 19 46383784 46383793 10 + 1.210 1.200 -0.036
ENSG00000011485 E019 32.6212343 0.0004984059 2.992922e-01 0.5921940522 19 46383794 46383878 85 + 1.491 1.560 0.236
ENSG00000011485 E020 0.8888560 0.0702325919 5.318254e-03 0.0517985242 19 46383879 46383998 120 + 0.000 0.446 14.305
ENSG00000011485 E021 2.2479839 0.0281445608 1.697019e-02 0.1137497806 19 46384377 46384803 427 + 0.287 0.661 1.935
ENSG00000011485 E022 36.2921079 0.0004407427 3.020016e-01 0.5952057955 19 46384804 46384909 106 + 1.538 1.604 0.225
ENSG00000011485 E023 0.1268540 0.0123009759 5.129532e-01   19 46384910 46384943 34 + 0.000 0.099 11.498
ENSG00000011485 E024 0.7608383 0.0359651224 8.927616e-03 0.0745474557 19 46386718 46387092 375 + 0.000 0.404 14.082
ENSG00000011485 E025 45.4127338 0.0040251967 1.263367e-01 0.3768509725 19 46387093 46387235 143 + 1.618 1.711 0.315
ENSG00000011485 E026 27.7452432 0.0289649587 4.617512e-01 0.7323162360 19 46387366 46387453 88 + 1.412 1.501 0.306
ENSG00000011485 E027 0.5002991 0.0259129172 2.993997e-01 0.5923098944 19 46387454 46387925 472 + 0.091 0.247 1.713
ENSG00000011485 E028 0.7537251 0.0133823583 8.228300e-02 0.2953837205 19 46387926 46388407 482 + 0.091 0.358 2.450
ENSG00000011485 E029 16.2780906 0.0077212293 8.838077e-01 0.9609464381 19 46388408 46388448 41 + 1.235 1.240 0.019
ENSG00000011485 E030 0.2537079 0.2964149198 2.896967e-01   19 46388449 46388552 104 + 0.000 0.179 12.497
ENSG00000011485 E031 44.1102297 0.0003464972 3.804556e-01 0.6670097652 19 46388553 46388731 179 + 1.665 1.643 -0.072
ENSG00000011485 E032 22.8615710 0.0006253543 2.038126e-02 0.1284311971 19 46390051 46390132 82 + 1.435 1.311 -0.432
ENSG00000011485 E033 0.8695004 0.0130641933 2.280303e-01 0.5164825039 19 46390133 46390283 151 + 0.167 0.358 1.450
ENSG00000011485 E034 32.5442946 0.0005293043 9.857130e-02 0.3275451805 19 46390284 46390975 692 + 1.558 1.490 -0.231
ENSG00000011485 E035 0.3543453 0.0156734609 1.129710e-01   19 46391151 46391258 108 + 0.231 0.000 -12.932
ENSG00000011485 E036 0.6245427 0.0434972219 1.634639e-01 0.4322757710 19 46392637 46392981 345 + 0.091 0.306 2.128

Help

Please Click HERE to learn more details about the results from DEXseq.