ENSG00000012822

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000546443 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding protein_coding 26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 3.9852060 5.9836858 4.6153066 3.8343200 1.5605049 -0.3738945 0.17442500 0.117075 0.311225 0.194150 0.62103238 0.03094944 FALSE TRUE
ENST00000548263 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding protein_coding 26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 5.1732154 12.0224727 1.3489933 0.1948764 0.1213766 -3.1463229 0.16373333 0.231600 0.087400 -0.144200 0.03094944 0.03094944 FALSE TRUE
ENST00000549935 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding retained_intron 26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 1.2767722 2.0625333 0.5886889 2.0625333 0.3779873 -1.7915167 0.05658333 0.039325 0.042100 0.002775 0.71145333 0.03094944 TRUE TRUE
ENST00000552282 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding retained_intron 26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 0.3415029 0.0000000 1.0245086 0.0000000 1.0245086 6.6928019 0.01944167 0.000000 0.058325 0.058325 0.67681881 0.03094944 FALSE FALSE
MSTRG.6573.10 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding   26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 2.2238015 5.1393503 0.5913150 1.7483989 0.4955701 -3.0981976 0.07138333 0.099625 0.034425 -0.065200 0.69969790 0.03094944 FALSE TRUE
MSTRG.6573.3 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding   26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 1.3156501 0.9839823 1.9003189 0.9839823 0.3204453 0.9425215 0.07255000 0.018200 0.123675 0.105475 0.04792073 0.03094944 TRUE TRUE
MSTRG.6573.5 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding   26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 7.1896262 15.8486310 1.9991324 4.2047011 1.9991324 -2.9806237 0.23926667 0.303700 0.113800 -0.189900 0.11185181 0.03094944 FALSE TRUE
MSTRG.6573.7 ENSG00000012822 No_inf pgKDN_inf CALCOCO1 protein_coding   26.78591 51.96334 15.56948 0.8825486 1.056184 -1.738124 2.1258594 3.6753967 1.7412170 0.3237062 0.7485991 -1.0734620 0.08996667 0.070650 0.121250 0.050600 0.92070504 0.03094944 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000012822 E001 3.6707511 0.0060464247 1.411704e-02 0.1007260907 12 53708517 53711117 2601 - 0.179 0.631 2.682
ENSG00000012822 E002 0.1265070 0.0123076767 1.000000e+00   12 53711118 53711118 1 - 0.000 0.048 8.496
ENSG00000012822 E003 2.4938865 0.0143013475 4.815671e-01 0.7466034122 12 53711119 53711158 40 - 0.551 0.441 -0.541
ENSG00000012822 E004 158.8628020 0.0001120301 3.872727e-02 0.1904088712 12 53711159 53712121 963 - 2.129 2.076 -0.175
ENSG00000012822 E005 31.0452957 0.0004308799 2.714857e-06 0.0001103415 12 53712122 53712774 653 - 1.050 1.439 1.372
ENSG00000012822 E006 9.9555749 0.0015027694 3.849766e-02 0.1896713906 12 53712775 53712846 72 - 0.707 0.969 1.024
ENSG00000012822 E007 20.1521998 0.0171459467 5.002526e-02 0.2208087812 12 53712847 53713099 253 - 1.030 1.244 0.766
ENSG00000012822 E008 18.5928275 0.0007822293 2.330121e-01 0.5217254737 12 53713100 53713169 70 - 1.088 1.198 0.392
ENSG00000012822 E009 10.6738243 0.0013010249 4.286977e-01 0.7071360760 12 53713170 53713203 34 - 0.884 0.975 0.344
ENSG00000012822 E010 6.4103500 0.0022092452 3.580514e-01 0.6475960995 12 53713204 53713206 3 - 0.661 0.789 0.526
ENSG00000012822 E011 0.6348960 0.0142019572 4.392969e-01 0.7152399783 12 53713537 53713700 164 - 0.000 0.200 10.663
ENSG00000012822 E012 31.7503545 0.0004594285 2.053654e-01 0.4886076536 12 53713701 53713900 200 - 1.464 1.386 -0.271
ENSG00000012822 E013 16.5208198 0.0008867511 2.546309e-03 0.0305183619 12 53713901 53714132 232 - 0.853 1.174 1.184
ENSG00000012822 E014 12.6112083 0.0060046819 3.028238e-01 0.5959461628 12 53714133 53714136 4 - 1.106 1.006 -0.364
ENSG00000012822 E015 34.3938989 0.0015683363 3.604502e-01 0.6501410797 12 53714137 53714241 105 - 1.479 1.424 -0.191
ENSG00000012822 E016 33.1621857 0.0005200048 5.418840e-01 0.7893578411 12 53714598 53714693 96 - 1.449 1.412 -0.126
ENSG00000012822 E017 30.9934537 0.0007334287 3.261666e-01 0.6186990033 12 53715200 53715325 126 - 1.331 1.402 0.246
ENSG00000012822 E018 0.1265070 0.0123076767 1.000000e+00   12 53715675 53715792 118 - 0.000 0.048 8.496
ENSG00000012822 E019 30.8438488 0.0004945889 5.395952e-01 0.7879758444 12 53715793 53716047 255 - 1.352 1.396 0.154
ENSG00000012822 E020 2.0231999 0.0071646017 1.592355e-01 0.4265694657 12 53716048 53716259 212 - 0.179 0.441 1.781
ENSG00000012822 E021 20.1222625 0.0006702954 3.046055e-01 0.5980022943 12 53716260 53716415 156 - 1.276 1.198 -0.278
ENSG00000012822 E022 8.9859028 0.0015777171 2.856837e-01 0.5793158958 12 53719739 53719771 33 - 0.986 0.872 -0.432
ENSG00000012822 E023 10.2411857 0.0014345687 2.961240e-01 0.5891891632 12 53719772 53719829 58 - 1.030 0.923 -0.396
ENSG00000012822 E024 15.9559693 0.0008845924 4.295076e-02 0.2020985259 12 53721467 53721615 149 - 1.252 1.084 -0.600
ENSG00000012822 E025 3.2644200 0.0046518970 6.719038e-01 0.8640342772 12 53721616 53722024 409 - 0.484 0.554 0.334
ENSG00000012822 E026 13.4188117 0.0036225778 6.452981e-01 0.8498609780 12 53722025 53722139 115 - 1.009 1.058 0.180
ENSG00000012822 E027 5.5023369 0.0397113128 7.539719e-01 0.9031878773 12 53722140 53722154 15 - 0.748 0.708 -0.167
ENSG00000012822 E028 4.8873550 0.0223551995 9.252005e-01 0.9774109547 12 53722155 53722163 9 - 0.661 0.677 0.067
ENSG00000012822 E029 5.3783688 0.0026403336 6.948236e-01 0.8753570268 12 53722164 53722183 20 - 0.748 0.698 -0.208
ENSG00000012822 E030 0.1265070 0.0123076767 1.000000e+00   12 53722900 53722936 37 - 0.000 0.048 8.496
ENSG00000012822 E031 0.4899798 0.0851650037 1.592898e-01   12 53723550 53723592 43 - 0.306 0.091 -2.126
ENSG00000012822 E032 4.5096264 0.0032311055 8.912106e-01 0.9637844245 12 53723593 53723593 1 - 0.661 0.643 -0.075
ENSG00000012822 E033 7.0056196 0.0021554526 5.880322e-01 0.8171846835 12 53723594 53723620 27 - 0.853 0.789 -0.251
ENSG00000012822 E034 6.7603792 0.0076169210 7.408683e-01 0.8971486014 12 53723621 53723639 19 - 0.821 0.781 -0.159
ENSG00000012822 E035 8.8988853 0.0163430518 9.869275e-01 0.9995483329 12 53723640 53723682 43 - 0.884 0.892 0.032
ENSG00000012822 E036 5.3888543 0.0208232820 9.724814e-01 0.9948269550 12 53723683 53723684 2 - 0.707 0.708 0.003
ENSG00000012822 E037 5.6587997 0.0361125358 4.251368e-01 0.7041960490 12 53723685 53723695 11 - 0.609 0.746 0.575
ENSG00000012822 E038 8.0355280 0.0018747469 5.402331e-01 0.7883246839 12 53723696 53723728 33 - 0.786 0.865 0.307
ENSG00000012822 E039 8.2867783 0.0016320850 4.660649e-01 0.7349065510 12 53723729 53723762 34 - 0.786 0.879 0.360
ENSG00000012822 E040 6.8741803 0.0389128743 5.868371e-01 0.8168561910 12 53723763 53723783 21 - 0.853 0.781 -0.284
ENSG00000012822 E041 0.6342667 0.0142506238 4.391231e-01 0.7151297522 12 53724044 53724251 208 - 0.000 0.200 10.663
ENSG00000012822 E042 1.2444535 0.0540999972 4.028685e-01 0.6859117459 12 53724404 53724582 179 - 0.404 0.260 -0.903
ENSG00000012822 E043 0.3721553 0.2250139844 4.895072e-01   12 53724583 53724584 2 - 0.179 0.091 -1.125
ENSG00000012822 E044 0.7444368 0.0138668243 3.891580e-01 0.6750344229 12 53724585 53724644 60 - 0.306 0.167 -1.126
ENSG00000012822 E045 14.5485628 0.0010274944 7.123844e-01 0.8838273161 12 53724645 53724747 103 - 1.050 1.088 0.137
ENSG00000012822 E046 1.2527958 0.1498038063 8.686247e-01 0.9548427306 12 53724748 53725086 339 - 0.306 0.287 -0.126
ENSG00000012822 E047 19.3217055 0.0011871388 4.157723e-02 0.1981992731 12 53725087 53725258 172 - 1.321 1.164 -0.553
ENSG00000012822 E048 5.4993433 0.0077144187 7.517417e-01 0.9021952541 12 53725259 53725263 5 - 0.748 0.708 -0.166
ENSG00000012822 E049 5.3724893 0.0100135831 6.978602e-01 0.8766923633 12 53725264 53725266 3 - 0.748 0.698 -0.208
ENSG00000012822 E050 0.0000000       12 53725267 53725267 1 -      
ENSG00000012822 E051 0.3720293 0.0165849917 4.770961e-01   12 53725690 53725759 70 - 0.179 0.091 -1.126
ENSG00000012822 E052 0.0000000       12 53726200 53726243 44 -      
ENSG00000012822 E053 0.0000000       12 53726244 53726334 91 -      
ENSG00000012822 E054 0.0000000       12 53726335 53726340 6 -      
ENSG00000012822 E055 5.4902460 0.0033776484 4.909016e-01 0.7533872096 12 53727404 53727745 342 - 0.786 0.698 -0.360

Help

Please Click HERE to learn more details about the results from DEXseq.