ENSG00000012983

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000557390 ENSG00000012983 No_inf pgKDN_inf MAP4K5 protein_coding nonsense_mediated_decay 6.302777 9.02386 5.29944 0.5558821 0.3499117 -0.7667829 0.4039111 0.0000000 1.2117332 0.0000000 0.5123132 6.9327855 0.07130833 0.000000 0.213925 0.213925 0.02709256 0.02709256 TRUE TRUE
ENST00000682126 ENSG00000012983 No_inf pgKDN_inf MAP4K5 protein_coding protein_coding 6.302777 9.02386 5.29944 0.5558821 0.3499117 -0.7667829 1.1504140 0.6684254 0.7416679 0.5172483 0.7416679 0.1479052 0.23199167 0.066975 0.156825 0.089850 0.94858506 0.02709256 FALSE TRUE
MSTRG.8514.1 ENSG00000012983 No_inf pgKDN_inf MAP4K5 protein_coding   6.302777 9.02386 5.29944 0.5558821 0.3499117 -0.7667829 2.2169131 3.8259085 1.1451652 1.0193747 0.6767366 -1.7314692 0.34425000 0.443000 0.225475 -0.217525 0.64657366 0.02709256 FALSE TRUE
MSTRG.8514.5 ENSG00000012983 No_inf pgKDN_inf MAP4K5 protein_coding   6.302777 9.02386 5.29944 0.5558821 0.3499117 -0.7667829 1.4152937 2.6815428 1.3081328 1.0302817 0.2085561 -1.0299376 0.19332500 0.283500 0.244050 -0.039450 1.00000000 0.02709256 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000012983 E001 0.0000000       14 50418496 50418500 5 -      
ENSG00000012983 E002 0.0000000       14 50418501 50418520 20 -      
ENSG00000012983 E003 0.2455571 0.0164490588 0.642353710   14 50418521 50418524 4 - 0.124 0.073 -0.859
ENSG00000012983 E004 1.4625387 0.2175251354 0.213130361 0.49835883 14 50418525 50418683 159 - 0.520 0.281 -1.346
ENSG00000012983 E005 30.1169585 0.0005866698 0.008523434 0.07210237 14 50418684 50419559 876 - 1.369 1.514 0.497
ENSG00000012983 E006 21.8187660 0.0014811508 0.189669441 0.46849698 14 50419560 50420106 547 - 1.387 1.307 -0.280
ENSG00000012983 E007 5.6322287 0.0029923782 0.044577985 0.20635731 14 50423121 50423176 56 - 0.934 0.714 -0.859
ENSG00000012983 E008 6.5448442 0.0094580800 0.547207716 0.79270363 14 50425907 50425977 71 - 0.899 0.834 -0.251
ENSG00000012983 E009 6.7618942 0.0070050775 0.017479253 0.11594220 14 50428662 50428754 93 - 0.665 0.945 1.108
ENSG00000012983 E010 5.2721346 0.0040988187 0.006938244 0.06272108 14 50429192 50429256 65 - 0.519 0.867 1.463
ENSG00000012983 E011 2.8768373 0.0507035546 0.210274561 0.49471943 14 50429257 50429260 4 - 0.423 0.631 0.990
ENSG00000012983 E012 8.4636257 0.0284829850 0.275958748 0.56934053 14 50434394 50434571 178 - 0.861 0.996 0.508
ENSG00000012983 E013 2.9650754 0.0047331471 0.840420953 0.94270753 14 50434962 50434963 2 - 0.598 0.571 -0.122
ENSG00000012983 E014 7.1721570 0.0020800678 0.913311962 0.97251578 14 50434964 50435065 102 - 0.899 0.888 -0.041
ENSG00000012983 E015 5.0757033 0.0040456694 0.852226972 0.94779211 14 50437476 50437534 59 - 0.749 0.771 0.089
ENSG00000012983 E016 5.6019120 0.0755646487 0.338254834 0.63004092 14 50437894 50438008 115 - 0.695 0.845 0.601
ENSG00000012983 E017 0.3714026 0.0166595255 1.000000000   14 50438009 50438091 83 - 0.124 0.135 0.142
ENSG00000012983 E018 2.1030714 0.0605445776 0.989547837 1.00000000 14 50438092 50438094 3 - 0.474 0.477 0.016
ENSG00000012983 E019 2.4841287 0.0072165109 0.607487242 0.82915330 14 50438095 50438401 307 - 0.474 0.550 0.364
ENSG00000012983 E020 3.3289958 0.0670350399 0.644594375 0.84951072 14 50440013 50440073 61 - 0.665 0.592 -0.318
ENSG00000012983 E021 4.6850392 0.0035080120 0.615777515 0.83330434 14 50440362 50440441 80 - 0.774 0.714 -0.242
ENSG00000012983 E022 4.5609200 0.0033741068 0.527667950 0.77953422 14 50442732 50442816 85 - 0.774 0.699 -0.306
ENSG00000012983 E023 3.8471634 0.0046003891 0.702805524 0.87912223 14 50443729 50443770 42 - 0.633 0.683 0.212
ENSG00000012983 E024 4.8167061 0.0031510312 0.703725240 0.87947718 14 50443939 50444036 98 - 0.774 0.729 -0.180
ENSG00000012983 E025 4.2349614 0.0063309130 0.267243466 0.56042261 14 50445041 50445194 154 - 0.598 0.744 0.615
ENSG00000012983 E026 2.9771968 0.0055515143 0.825361986 0.93674999 14 50446079 50446121 43 - 0.561 0.592 0.141
ENSG00000012983 E027 2.9344840 0.0330789887 0.083224552 0.29728168 14 50447414 50447481 68 - 0.723 0.477 -1.100
ENSG00000012983 E028 0.7279436 0.1633768073 0.175861996 0.44999320 14 50448774 50448832 59 - 0.365 0.135 -1.859
ENSG00000012983 E029 2.1412124 0.0327804712 0.033283662 0.17342489 14 50448833 50450600 1768 - 0.220 0.571 2.048
ENSG00000012983 E030 0.1271363 0.0124026574 1.000000000   14 50453197 50453256 60 - 0.000 0.073 9.803
ENSG00000012983 E031 0.0000000       14 50456516 50456594 79 -      
ENSG00000012983 E032 0.4896324 0.0162695624 0.555367277   14 50462665 50462692 28 - 0.220 0.135 -0.859
ENSG00000012983 E033 1.2324699 0.0103494179 0.770897076 0.91163594 14 50462693 50462781 89 - 0.365 0.320 -0.274
ENSG00000012983 E034 1.4574389 0.0856808350 0.160240485 0.42790565 14 50464052 50464077 26 - 0.519 0.281 -1.343
ENSG00000012983 E035 3.0618080 0.0084857286 0.210144212 0.49458029 14 50464078 50464133 56 - 0.695 0.527 -0.743
ENSG00000012983 E036 3.0658019 0.0052859168 0.204218654 0.48702642 14 50466583 50466645 63 - 0.695 0.527 -0.743
ENSG00000012983 E037 2.3329147 0.0239088507 0.309492556 0.60280133 14 50468651 50468689 39 - 0.598 0.450 -0.707
ENSG00000012983 E038 3.8191512 0.0130974119 0.474150493 0.74091939 14 50468690 50468782 93 - 0.723 0.631 -0.389
ENSG00000012983 E039 1.9938055 0.0087547510 0.371686581 0.65966449 14 50475077 50475091 15 - 0.365 0.503 0.726
ENSG00000012983 E040 3.0989818 0.0047660978 0.711347776 0.88333927 14 50475092 50475149 58 - 0.561 0.612 0.229
ENSG00000012983 E041 2.9520530 0.0409527093 0.585839239 0.81615575 14 50476128 50476170 43 - 0.633 0.550 -0.373
ENSG00000012983 E042 3.1694391 0.0131412401 0.066380155 0.25950618 14 50476259 50476306 48 - 0.749 0.503 -1.081
ENSG00000012983 E043 3.1892343 0.0045464231 0.268451308 0.56197224 14 50482361 50482416 56 - 0.695 0.550 -0.636
ENSG00000012983 E044 1.1157452 0.0487560686 0.897306986 0.96613081 14 50482652 50483149 498 - 0.299 0.320 0.141
ENSG00000012983 E045 2.5817803 0.0056556723 0.491167449 0.75354064 14 50485578 50485642 65 - 0.598 0.503 -0.443
ENSG00000012983 E046 0.1272623 0.0124067173 1.000000000   14 50485929 50486103 175 - 0.000 0.073 9.803
ENSG00000012983 E047 2.2377850 0.0786702498 0.570176591 0.80688366 14 50486104 50486194 91 - 0.423 0.527 0.520
ENSG00000012983 E048 1.3528608 0.1863975307 0.571580819 0.80774974 14 50504800 50504857 58 - 0.423 0.320 -0.595
ENSG00000012983 E049 0.0000000       14 50504858 50505128 271 -      
ENSG00000012983 E050 3.1961118 0.1658949108 0.412786603 0.69378421 14 50531942 50532158 217 - 0.695 0.550 -0.637
ENSG00000012983 E051 0.1176306 0.0117521365 0.285279860   14 50532400 50532447 48 - 0.124 0.000 -11.763
ENSG00000012983 E052 0.2448930 0.0163351550 0.642313990   14 50532448 50532619 172 - 0.124 0.073 -0.859
ENSG00000012983 E053 0.2545247 0.2346762588 0.583594275   14 50542499 50542584 86 - 0.000 0.135 10.499
ENSG00000012983 E054 0.1272623 0.0124067173 1.000000000   14 50561040 50561126 87 - 0.000 0.073 9.803

Help

Please Click HERE to learn more details about the results from DEXseq.