ENSG00000013375

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000507404 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding retained_intron 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 14.0060817 0.0000000 15.61957690 0.0000000 6.38368327 10.6100630 0.30111667 0.000000 0.486025 0.486025 0.00873224 0.00873224   FALSE
ENST00000513973 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding protein_coding 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 3.0717360 2.2958794 3.94573870 0.7868848 0.08545666 0.7786301 0.23990833 0.349650 0.194925 -0.154725 0.82396809 0.00873224 FALSE TRUE
ENST00000651425 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding protein_coding 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 0.6414654 0.0000000 1.92439632 0.0000000 1.14603314 7.5957396 0.02025833 0.000000 0.060775 0.060775 0.69370101 0.00873224 FALSE TRUE
ENST00000698525 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding protein_coding 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 0.2514779 0.4484028 0.03023062 0.1771996 0.03023062 -3.5102500 0.03322500 0.076475 0.001200 -0.075275 0.07833918 0.00873224 FALSE TRUE
ENST00000698605 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding nonsense_mediated_decay 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 0.2528884 0.7586651 0.00000000 0.7586651 0.00000000 -6.2642832 0.04661667 0.139850 0.000000 -0.139850 0.73842631 0.00873224 FALSE TRUE
ENST00000698610 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding protein_coding 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 0.7343993 0.0000000 1.24414844 0.0000000 0.81768821 6.9705643 0.05216667 0.000000 0.098375 0.098375 0.83124781 0.00873224 FALSE TRUE
ENST00000698616 ENSG00000013375 No_inf pgKDN_inf PGM3 protein_coding retained_intron 22.61353 6.299029 26.11639 0.3730993 6.469862 2.050018 0.4269431 0.7742381 0.23853630 0.3450347 0.17125800 -1.6578351 0.04550000 0.114400 0.018875 -0.095525 0.26841813 0.00873224 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000013375 E001 1.3595077 0.009830457 0.145266299 0.40552757 6 83147324 83150456 3133 - 0.259 0.486 1.341
ENSG00000013375 E002 0.0000000       6 83150754 83150755 2 -      
ENSG00000013375 E003 1.2398658 0.091783957 0.105484962 0.33978356 6 83150756 83151839 1084 - 0.207 0.486 1.756
ENSG00000013375 E004 0.1271363 0.012301895 0.379081706   6 83151840 83151894 55 - 0.000 0.112 13.177
ENSG00000013375 E005 0.1272623 0.012486123 0.378775451   6 83151895 83152057 163 - 0.000 0.112 13.176
ENSG00000013375 E006 0.0000000       6 83153453 83153539 87 -      
ENSG00000013375 E007 0.1271363 0.012301895 0.379081706   6 83161113 83161149 37 - 0.000 0.112 13.177
ENSG00000013375 E008 0.1271363 0.012301895 0.379081706   6 83161150 83161242 93 - 0.000 0.112 13.177
ENSG00000013375 E009 0.2530140 0.243847947 0.189065071   6 83164873 83164894 22 - 0.000 0.201 13.803
ENSG00000013375 E010 0.2530140 0.243847947 0.189065071   6 83164895 83164903 9 - 0.000 0.201 13.803
ENSG00000013375 E011 0.2530140 0.243847947 0.189065071   6 83164904 83164910 7 - 0.000 0.201 13.803
ENSG00000013375 E012 1.8338127 0.018717332 0.696135561 0.87604054 6 83164911 83165013 103 - 0.420 0.486 0.341
ENSG00000013375 E013 1.7080610 0.009117050 0.920222664 0.97521456 6 83165014 83165034 21 - 0.420 0.442 0.119
ENSG00000013375 E014 3.6680701 0.004495789 0.573093356 0.80875510 6 83165035 83165180 146 - 0.629 0.710 0.341
ENSG00000013375 E015 18.1407156 0.022582277 0.058398171 0.24200130 6 83165181 83166129 949 - 1.194 1.369 0.613
ENSG00000013375 E016 5.5611441 0.003283104 0.005519201 0.05318431 6 83166130 83166309 180 - 0.649 0.966 1.254
ENSG00000013375 E017 3.9271530 0.003987133 0.190986175 0.47032776 6 83166310 83166466 157 - 0.608 0.779 0.715
ENSG00000013375 E018 1.6913812 0.008715071 0.318188699 0.61096517 6 83166467 83166488 22 - 0.482 0.338 -0.788
ENSG00000013375 E019 3.1626367 0.014894956 0.757372155 0.90459983 6 83166489 83166598 110 - 0.629 0.596 -0.144
ENSG00000013375 E020 1.2150619 0.011289363 0.920315105 0.97521456 6 83166599 83166600 2 - 0.346 0.338 -0.051
ENSG00000013375 E021 1.3326925 0.029863545 0.733214173 0.89389760 6 83166601 83166603 3 - 0.384 0.338 -0.273
ENSG00000013375 E022 29.8697139 0.017513691 0.627586880 0.83998598 6 83166604 83167793 1190 - 1.495 1.471 -0.085
ENSG00000013375 E023 1.4614357 0.100209830 0.994748120 1.00000000 6 83167794 83167926 133 - 0.385 0.393 0.049
ENSG00000013375 E024 0.0000000       6 83167927 83168057 131 -      
ENSG00000013375 E025 0.0000000       6 83168058 83168243 186 -      
ENSG00000013375 E026 0.0000000       6 83168244 83168266 23 -      
ENSG00000013375 E027 0.0000000       6 83168267 83168363 97 -      
ENSG00000013375 E028 0.0000000       6 83168364 83168527 164 -      
ENSG00000013375 E029 0.0000000       6 83168528 83168714 187 -      
ENSG00000013375 E030 0.0000000       6 83168715 83168744 30 -      
ENSG00000013375 E031 1.3337298 0.091163058 0.780940222 0.91565534 6 83168745 83168846 102 - 0.385 0.338 -0.273
ENSG00000013375 E032 3.5941045 0.073830878 0.041944922 0.19928272 6 83168847 83168902 56 - 0.770 0.442 -1.466
ENSG00000013375 E033 2.5045123 0.005759548 0.007086510 0.06358406 6 83168903 83168908 6 - 0.669 0.275 -2.051
ENSG00000013375 E034 2.9859939 0.004793153 0.006222737 0.05794530 6 83168909 83168927 19 - 0.722 0.338 -1.858
ENSG00000013375 E035 5.9138046 0.002458568 0.114714124 0.35700108 6 83168928 83168972 45 - 0.898 0.734 -0.647
ENSG00000013375 E036 4.0077102 0.003649268 0.803474029 0.92693217 6 83168973 83168973 1 - 0.705 0.684 -0.087
ENSG00000013375 E037 6.7048022 0.002194610 0.754425061 0.90338880 6 83168974 83169062 89 - 0.864 0.907 0.165
ENSG00000013375 E038 4.3611207 0.008793326 0.510366123 0.76800524 6 83169063 83169122 60 - 0.754 0.684 -0.289
ENSG00000013375 E039 8.3349066 0.002511645 0.097477760 0.32533203 6 83169123 83169241 119 - 1.024 0.874 -0.561
ENSG00000013375 E040 3.7577266 0.003933163 0.492282965 0.75449814 6 83169242 83169323 82 - 0.705 0.627 -0.328
ENSG00000013375 E041 1.0972739 0.029289073 0.861173743 0.95185395 6 83169324 83169520 197 - 0.305 0.338 0.212
ENSG00000013375 E042 0.0000000       6 83169521 83169568 48 -      
ENSG00000013375 E043 0.2541163 0.016174002 0.145700379   6 83169569 83169841 273 - 0.000 0.201 14.058
ENSG00000013375 E044 1.0046931 0.095963454 0.013334875 0.09691275 6 83169842 83170300 459 - 0.080 0.486 3.341
ENSG00000013375 E045 0.0000000       6 83170301 83170304 4 -      
ENSG00000013375 E046 0.0000000       6 83170305 83170478 174 -      
ENSG00000013375 E047 0.0000000       6 83171495 83171587 93 -      
ENSG00000013375 E048 0.0000000       6 83171588 83171635 48 -      
ENSG00000013375 E049 0.1271363 0.012301895 0.379081706   6 83171636 83171690 55 - 0.000 0.112 13.177
ENSG00000013375 E050 0.1271363 0.012301895 0.379081706   6 83171691 83171936 246 - 0.000 0.112 13.177
ENSG00000013375 E051 4.2626493 0.003763612 0.875127914 0.95732813 6 83171937 83172055 119 - 0.705 0.734 0.119
ENSG00000013375 E052 2.4229176 0.009588424 0.559896199 0.80065281 6 83172056 83172059 4 - 0.562 0.486 -0.359
ENSG00000013375 E053 1.3524280 0.010464853 0.390877464 0.67614938 6 83172060 83174373 2314 - 0.305 0.442 0.797
ENSG00000013375 E054 4.1142690 0.017323579 0.300192064 0.59306076 6 83174374 83174436 63 - 0.754 0.627 -0.530
ENSG00000013375 E055 3.7561851 0.009371665 0.494931873 0.75630043 6 83174437 83174487 51 - 0.705 0.627 -0.328
ENSG00000013375 E056 2.1053016 0.007094616 0.057147384 0.23896627 6 83174488 83175961 1474 - 0.346 0.627 1.409
ENSG00000013375 E057 6.3028032 0.003973509 0.462109661 0.73264994 6 83175962 83176060 99 - 0.887 0.819 -0.262
ENSG00000013375 E058 0.4726025 0.016341497 0.095074709   6 83176061 83176135 75 - 0.259 0.000 -14.766
ENSG00000013375 E059 5.3309647 0.002720508 0.482758561 0.74767332 6 83178673 83178756 84 - 0.826 0.757 -0.273
ENSG00000013375 E060 9.7559709 0.001473036 0.686500519 0.87049699 6 83179810 83179967 158 - 1.007 1.053 0.171
ENSG00000013375 E061 1.3702093 0.009935101 0.038292344 0.18894589 6 83180357 83181735 1379 - 0.207 0.526 1.949
ENSG00000013375 E062 4.8747593 0.002930279 0.902781845 0.96886466 6 83181736 83181761 26 - 0.754 0.779 0.098
ENSG00000013375 E063 8.5749829 0.001647439 0.064813045 0.25657842 6 83181762 83181931 170 - 1.040 0.874 -0.621
ENSG00000013375 E064 0.7246754 0.014104784 0.682730630 0.86858482 6 83182280 83182790 511 - 0.259 0.201 -0.466
ENSG00000013375 E065 0.1268540 0.012353368 0.378900426   6 83182791 83182844 54 - 0.000 0.112 13.177
ENSG00000013375 E066 5.3007475 0.002803699 0.049235089 0.21873538 6 83182845 83182978 134 - 0.876 0.657 -0.881
ENSG00000013375 E067 3.8772679 0.003842068 0.408638156 0.69089311 6 83187008 83187075 68 - 0.722 0.627 -0.399
ENSG00000013375 E068 2.6054119 0.005759628 0.021389657 0.13246797 6 83187076 83188502 1427 - 0.385 0.710 1.534
ENSG00000013375 E069 0.2454921 0.016300607 0.790025421   6 83188503 83188613 111 - 0.080 0.112 0.534
ENSG00000013375 E070 2.4136942 0.005957942 0.289353602 0.58294413 6 83188614 83188626 13 - 0.585 0.442 -0.688
ENSG00000013375 E071 6.7151135 0.002346453 0.557779733 0.79961969 6 83188627 83188744 118 - 0.851 0.922 0.271
ENSG00000013375 E072 4.6614509 0.023576025 0.202700375 0.48519626 6 83188745 83188794 50 - 0.668 0.838 0.686
ENSG00000013375 E073 2.5471201 0.021611278 0.755503061 0.90360806 6 83188795 83188798 4 - 0.562 0.526 -0.166
ENSG00000013375 E074 4.5374413 0.003110517 0.231196754 0.51970849 6 83188799 83190509 1711 - 0.669 0.819 0.612
ENSG00000013375 E075 0.2536433 0.016013784 0.145990663   6 83190510 83190808 299 - 0.000 0.201 14.058
ENSG00000013375 E076 7.7795281 0.002575472 0.684634443 0.86954136 6 83190809 83191014 206 - 0.951 0.922 -0.108
ENSG00000013375 E077 0.1268540 0.012353368 0.378900426   6 83191187 83191323 137 - 0.000 0.112 13.177
ENSG00000013375 E078 0.0000000       6 83192962 83193104 143 -      
ENSG00000013375 E079 0.0000000       6 83193105 83193178 74 -      
ENSG00000013375 E080 1.9437347 0.007443977 0.742083076 0.89791856 6 83193179 83193293 115 - 0.482 0.442 -0.203
ENSG00000013375 E081 0.2537694 0.016163135 0.145706719   6 83193823 83193936 114 - 0.000 0.201 14.058

Help

Please Click HERE to learn more details about the results from DEXseq.