ENSG00000014257

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336375 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding protein_coding 14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 6.2339696 15.045990 2.2183431 0.3407202 0.2279934 -2.7562943 0.3680583 0.482950 0.293175 -0.189775 0.299613199 0.002250867 FALSE TRUE
ENST00000351273 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding protein_coding 14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 0.6078738 0.000000 1.3326012 0.0000000 0.4735488 7.0688871 0.0861000 0.000000 0.151675 0.151675 0.002250867 0.002250867 FALSE TRUE
ENST00000495911 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding protein_coding 14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 0.7292573 1.220355 0.9674169 1.2203550 0.9674169 -0.3320287 0.0409250 0.034650 0.088125 0.053475 0.849854281 0.002250867 FALSE FALSE
ENST00000507647 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding protein_coding 14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 0.2198338 0.000000 0.6595013 0.0000000 0.6595013 6.0650148 0.0240000 0.000000 0.072000 0.072000 0.639572590 0.002250867 FALSE FALSE
MSTRG.20750.10 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding   14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 5.1498861 13.450239 1.5532883 1.3045702 0.8990362 -3.1060483 0.2577583 0.429600 0.242050 -0.187550 0.553464890 0.002250867 FALSE TRUE
MSTRG.20750.2 ENSG00000014257 No_inf pgKDN_inf ACP3 protein_coding   14.68497 31.32228 8.281559 1.312323 1.120566 -1.917935 1.5243265 1.392940 1.5504083 1.3929396 0.9176154 0.1534707 0.1895417 0.046775 0.153000 0.106225 0.557881422 0.002250867 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000014257 E001 0.1271363 0.0123832176 0.7778479795   3 132317369 132317405 37 + 0.000 0.045 7.942
ENSG00000014257 E002 0.1271363 0.0123832176 0.7778479795   3 132317406 132317406 1 + 0.000 0.045 9.765
ENSG00000014257 E003 0.7612770 0.0192620127 0.4157783742 0.695810822 3 132317407 132317425 19 + 0.000 0.217 12.162
ENSG00000014257 E004 1.0152673 0.0363713262 0.2528168692 0.544121640 3 132317426 132317436 11 + 0.000 0.271 12.475
ENSG00000014257 E005 5.8998313 0.0032324079 0.7893674643 0.919161985 3 132317437 132317576 140 + 0.688 0.727 0.162
ENSG00000014257 E006 8.4202833 0.0018813058 0.5119704520 0.769106266 3 132328267 132328323 57 + 0.777 0.862 0.335
ENSG00000014257 E007 7.2947142 0.0022915834 0.3633628649 0.652335549 3 132328324 132328362 39 + 0.688 0.814 0.512
ENSG00000014257 E008 9.9725340 0.0013846696 0.0467209611 0.212197753 3 132331647 132331733 87 + 1.082 0.875 -0.768
ENSG00000014257 E009 16.7112606 0.0016021085 0.0135116455 0.097764568 3 132332192 132332344 153 + 1.285 1.077 -0.739
ENSG00000014257 E010 0.1271363 0.0123832176 0.7778479795   3 132332345 132332626 282 + 0.000 0.045 9.765
ENSG00000014257 E011 0.3802764 0.0270660805 1.0000000000   3 132333406 132333492 87 + 0.000 0.122 11.216
ENSG00000014257 E012 0.0000000       3 132337352 132337455 104 +      
ENSG00000014257 E013 6.6412100 0.0022347564 0.6214819904 0.836687814 3 132337456 132337475 20 + 0.815 0.753 -0.249
ENSG00000014257 E014 10.4926304 0.0013220584 0.1332368835 0.387703359 3 132337476 132337554 79 + 1.061 0.905 -0.578
ENSG00000014257 E015 0.1271363 0.0123832176 0.7778479795   3 132338658 132338688 31 + 0.000 0.045 9.765
ENSG00000014257 E016 10.7708330 0.0245885613 0.6214691543 0.836687814 3 132342552 132342613 62 + 0.993 0.933 -0.224
ENSG00000014257 E017 8.2527062 0.0294935770 0.3446957303 0.635822774 3 132342614 132342644 31 + 0.942 0.822 -0.460
ENSG00000014257 E018 19.3144786 0.0010648438 0.8459492389 0.945252056 3 132344927 132345059 133 + 1.187 1.172 -0.053
ENSG00000014257 E019 15.3264530 0.0012388800 0.4644992727 0.733979299 3 132349920 132350002 83 + 1.017 1.092 0.274
ENSG00000014257 E020 15.2349611 0.0013988600 0.0783119632 0.286499044 3 132352720 132352801 82 + 0.913 1.104 0.702
ENSG00000014257 E021 10.3081037 0.0054159339 0.4707693568 0.738352754 3 132352802 132352823 22 + 0.850 0.939 0.337
ENSG00000014257 E022 24.6520180 0.0006186525 0.1885070841 0.466887448 3 132356686 132356855 170 + 1.354 1.258 -0.335
ENSG00000014257 E023 76.1802757 0.0003094398 0.0003941697 0.007208934 3 132356856 132358416 1561 + 1.599 1.770 0.581
ENSG00000014257 E024 18.3413520 0.0007984830 0.6783175423 0.866825692 3 132358417 132358841 425 + 1.120 1.159 0.142
ENSG00000014257 E025 49.0441367 0.0003752065 0.0355528257 0.180607149 3 132367704 132368706 1003 + 1.650 1.543 -0.367
ENSG00000014257 E026 145.9422848 0.0001359974 0.8705301708 0.955410896 3 132368707 132371754 3048 + 2.021 2.028 0.022

Help

Please Click HERE to learn more details about the results from DEXseq.