ENSG00000023287

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000435644 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding protein_coding 22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 0.8750763 0.5483291 0.000000 0.5483291 0.000000 -5.8030437 0.06314167 0.026100 0.000000 -0.026100 0.936365889 0.008947711 FALSE TRUE
ENST00000519912 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding protein_coding 22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 4.6975528 10.3155480 0.000000 4.1848267 0.000000 -10.0120026 0.16211667 0.291900 0.000000 -0.291900 0.008947711 0.008947711 FALSE TRUE
MSTRG.27664.1 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding   22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 8.6728446 11.7501306 9.775211 0.6766736 0.663450 -0.2652292 0.38847500 0.396675 0.495750 0.099075 0.709420918 0.008947711 FALSE TRUE
MSTRG.27664.4 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding   22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 1.4106906 1.2093350 3.022737 1.2093350 1.866358 1.3145257 0.06178333 0.038300 0.147050 0.108750 0.742843428 0.008947711 FALSE TRUE
MSTRG.27664.8 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding   22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 1.9171871 1.8048522 3.946709 1.8048522 1.354456 1.1244489 0.08762500 0.058500 0.204375 0.145875 0.271086158 0.008947711 FALSE TRUE
MSTRG.27664.9 ENSG00000023287 No_inf pgKDN_inf RB1CC1 protein_coding   22.26304 31.05812 19.68002 4.041966 0.5617509 -0.65797 2.4625826 2.0195512 1.454963 2.0195512 1.454963 -0.4702969 0.13649167 0.096125 0.077000 -0.019125 0.970925808 0.008947711 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000023287 E001 0.0000000       8 52622458 52622458 1 -      
ENSG00000023287 E002 0.0000000       8 52622459 52622468 10 -      
ENSG00000023287 E003 1.2187109 0.0107363866 0.33746361 0.62924308 8 52622469 52622511 43 - 0.421 0.274 -0.892
ENSG00000023287 E004 83.8240471 0.0002836078 0.02658530 0.15113857 8 52622512 52623328 817 - 1.882 1.954 0.243
ENSG00000023287 E005 36.7368181 0.0093282697 0.25587733 0.54796459 8 52623329 52623471 143 - 1.531 1.602 0.242
ENSG00000023287 E006 30.4184182 0.0006072216 0.01002149 0.08043091 8 52623472 52623583 112 - 1.407 1.548 0.487
ENSG00000023287 E007 32.3439449 0.0073846189 0.78191382 0.91609984 8 52623584 52623713 130 - 1.509 1.526 0.058
ENSG00000023287 E008 15.7241204 0.0008726320 0.88769621 0.96241665 8 52623714 52623727 14 - 1.225 1.215 -0.035
ENSG00000023287 E009 33.0325247 0.0004801269 0.73240903 0.89363131 8 52623728 52623859 132 - 1.538 1.520 -0.059
ENSG00000023287 E010 20.9509621 0.0007356464 0.35683964 0.64665645 8 52624717 52624787 71 - 1.302 1.362 0.208
ENSG00000023287 E011 4.9402821 0.0042899886 0.55755627 0.79945197 8 52628032 52628040 9 - 0.729 0.798 0.278
ENSG00000023287 E012 29.7738591 0.0006025770 0.88282871 0.96056072 8 52628041 52628168 128 - 1.479 1.487 0.029
ENSG00000023287 E013 22.2671586 0.0006206329 0.89480561 0.96526683 8 52630470 52630528 59 - 1.357 1.366 0.030
ENSG00000023287 E014 17.8917874 0.0008001822 0.25651865 0.54856087 8 52634921 52634968 48 - 1.225 1.304 0.278
ENSG00000023287 E015 15.0945174 0.0009036618 0.05447779 0.23247134 8 52636015 52636069 55 - 1.113 1.259 0.519
ENSG00000023287 E016 42.0607481 0.0003342602 0.84015730 0.94258822 8 52642351 52642591 241 - 1.624 1.634 0.032
ENSG00000023287 E017 24.5733316 0.0005538237 0.92969528 0.97937143 8 52642704 52642812 109 - 1.407 1.402 -0.017
ENSG00000023287 E018 0.4992614 0.0152890144 0.43234093   8 52642813 52643243 431 - 0.105 0.220 1.278
ENSG00000023287 E019 28.6640587 0.0004665111 0.77893937 0.91499838 8 52645702 52645867 166 - 1.459 1.475 0.054
ENSG00000023287 E020 245.2973156 0.0001063663 0.20365437 0.48627673 8 52656008 52657884 1877 - 2.399 2.378 -0.071
ENSG00000023287 E021 9.6279608 0.0014688809 0.38208978 0.66831189 8 52657885 52657908 24 - 0.975 1.055 0.294
ENSG00000023287 E022 16.8417489 0.0071579353 0.89314633 0.96451864 8 52657998 52658124 127 - 1.252 1.243 -0.032
ENSG00000023287 E023 15.8494512 0.0008746436 0.95096649 0.98754784 8 52658873 52658976 104 - 1.225 1.221 -0.015
ENSG00000023287 E024 12.8740467 0.0015111040 0.55184976 0.79554829 8 52660596 52660657 62 - 1.165 1.117 -0.169
ENSG00000023287 E025 12.1544662 0.0151992902 0.89487827 0.96529080 8 52660926 52661007 82 - 1.122 1.110 -0.043
ENSG00000023287 E026 18.8887330 0.0046408442 0.43376040 0.71106179 8 52661095 52661281 187 - 1.325 1.270 -0.194
ENSG00000023287 E027 21.5250739 0.0077298614 0.07551413 0.28074418 8 52661535 52661719 185 - 1.416 1.290 -0.438
ENSG00000023287 E028 17.3745627 0.0159429904 0.57525865 0.80978232 8 52668021 52668191 171 - 1.232 1.280 0.168
ENSG00000023287 E029 25.2711333 0.0006002496 0.00664347 0.06079214 8 52673845 52674274 430 - 1.498 1.341 -0.544
ENSG00000023287 E030 6.3485937 0.0024611040 0.19124325 0.47068336 8 52676369 52676423 55 - 0.936 0.798 -0.529
ENSG00000023287 E031 8.5604256 0.0018199054 0.26379959 0.55696876 8 52676424 52676528 105 - 1.033 0.929 -0.389
ENSG00000023287 E032 4.0460186 0.0040178222 0.66590437 0.86104112 8 52676529 52676571 43 - 0.729 0.676 -0.219
ENSG00000023287 E033 5.9346277 0.0145276911 0.34998643 0.64020252 8 52683549 52683603 55 - 0.771 0.881 0.430
ENSG00000023287 E034 5.7527865 0.0024812625 0.38556688 0.67150491 8 52683604 52683687 84 - 0.877 0.783 -0.368
ENSG00000023287 E035 3.2849558 0.0255837413 0.15827391 0.42519112 8 52683688 52683719 32 - 0.729 0.534 -0.847
ENSG00000023287 E036 6.2939672 0.0111033218 0.46028832 0.73175060 8 52683887 52683949 63 - 0.809 0.893 0.326
ENSG00000023287 E037 6.6461121 0.0021373934 0.75867352 0.90525204 8 52683950 52684013 64 - 0.861 0.893 0.124
ENSG00000023287 E038 3.4123801 0.0043499495 0.19234576 0.47227002 8 52685399 52685423 25 - 0.729 0.561 -0.722
ENSG00000023287 E039 5.1559445 0.0061026706 0.70977613 0.88262164 8 52685424 52685520 97 - 0.809 0.767 -0.169
ENSG00000023287 E040 0.4814165 0.0268933349 0.23048178   8 52685937 52686156 220 - 0.259 0.086 -1.892
ENSG00000023287 E041 4.6682608 0.0521835611 0.77493690 0.91353804 8 52686853 52686945 93 - 0.771 0.733 -0.155
ENSG00000023287 E042 1.4522094 0.0304344906 0.14189783 0.40079169 8 52686946 52686967 22 - 0.502 0.274 -1.307
ENSG00000023287 E043 7.0505690 0.0020791861 0.01793586 0.11802992 8 52714075 52714466 392 - 1.022 0.783 -0.912
ENSG00000023287 E044 0.0000000       8 52745549 52745843 295 -      

Help

Please Click HERE to learn more details about the results from DEXseq.