ENSG00000023734

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000419869 ENSG00000023734 No_inf pgKDN_inf STRAP protein_coding protein_coding 51.98243 38.61367 60.37149 1.239972 2.433172 0.6446211 43.778559 27.576489 50.752381 1.306721 6.769749 0.8797979 0.82798333 0.718900 0.835250 0.116350 0.73048867 0.00797074 FALSE TRUE
ENST00000538718 ENSG00000023734 No_inf pgKDN_inf STRAP protein_coding protein_coding 51.98243 38.61367 60.37149 1.239972 2.433172 0.6446211 2.221393 5.978031 0.000000 2.311910 0.000000 -9.2259379 0.05632500 0.156475 0.000000 -0.156475 0.00797074 0.00797074   FALSE
ENST00000541731 ENSG00000023734 No_inf pgKDN_inf STRAP protein_coding nonsense_mediated_decay 51.98243 38.61367 60.37149 1.239972 2.433172 0.6446211 4.516693 2.418201 8.451563 1.929196 5.391277 1.8010364 0.08475833 0.060250 0.146325 0.086075 0.99570117 0.00797074 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000023734 E001 0.0000000       12 15882387 15882390 4 +      
ENSG00000023734 E002 0.2373413 0.0156278083 0.4639954565   12 15882391 15882393 3 + 0.141 0.000 -10.335
ENSG00000023734 E003 50.8850123 0.0231851388 0.9078362506 0.97069859 12 15882394 15882819 426 + 1.702 1.711 0.033
ENSG00000023734 E004 0.0000000       12 15883083 15883121 39 +      
ENSG00000023734 E005 32.3489020 0.0119958691 0.5119134910 0.76908945 12 15883541 15883676 136 + 1.497 1.538 0.142
ENSG00000023734 E006 28.5323769 0.0006850905 0.9971349598 1.00000000 12 15889928 15890009 82 + 1.461 1.461 -0.001
ENSG00000023734 E007 31.9909881 0.0004581334 0.3631792076 0.65217940 12 15890597 15890669 73 + 1.528 1.479 -0.166
ENSG00000023734 E008 36.8629767 0.0007264244 0.5336206048 0.78407600 12 15894047 15894143 97 + 1.581 1.550 -0.106
ENSG00000023734 E009 43.0813253 0.0003507088 0.9516694354 0.98784548 12 15895359 15895453 95 + 1.636 1.633 -0.009
ENSG00000023734 E010 33.7326117 0.0034694162 0.8657904771 0.95372968 12 15895454 15895496 43 + 1.535 1.526 -0.030
ENSG00000023734 E011 44.0310973 0.0003219911 0.0580656266 0.24122421 12 15897882 15897944 63 + 1.676 1.590 -0.293
ENSG00000023734 E012 44.6181236 0.0017512649 0.0371259180 0.18555734 12 15897945 15898018 74 + 1.687 1.587 -0.340
ENSG00000023734 E013 0.4896297 0.0157935616 0.6250251768   12 15898019 15898272 254 + 0.141 0.211 0.713
ENSG00000023734 E014 72.3469745 0.0002102883 0.9402981373 0.98303567 12 15899904 15900053 150 + 1.857 1.854 -0.008
ENSG00000023734 E015 0.3549069 0.0242593706 0.2414992186   12 15900899 15900946 48 + 0.197 0.000 -10.919
ENSG00000023734 E016 36.5196256 0.0004297609 0.8034331955 0.92693217 12 15900947 15901012 66 + 1.570 1.557 -0.042
ENSG00000023734 E017 123.5214517 0.0001370876 0.0008045615 0.01266216 12 15902917 15903478 562 + 2.051 2.134 0.277

Help

Please Click HERE to learn more details about the results from DEXseq.