ENSG00000025796

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369002 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding protein_coding 166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 10.060990 13.461188 8.923980 0.3063104 0.1525766 -0.5925021 0.06481667 0.103700 0.048875 -0.054825 0.045080952 0.001086748 FALSE TRUE
ENST00000473746 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding retained_intron 166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 7.306983 11.543517 2.875567 1.4993974 0.8042139 -2.0014054 0.04782500 0.088075 0.015750 -0.072325 0.001086748 0.001086748   FALSE
ENST00000484803 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding retained_intron 166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 16.739259 1.412458 22.800771 1.4124583 2.2597332 4.0032570 0.09179167 0.010875 0.124325 0.113450 0.002293347 0.001086748 FALSE TRUE
MSTRG.25090.14 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding   166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 3.298189 9.894568 0.000000 9.8945682 0.0000000 -9.9519503 0.02015833 0.060475 0.000000 -0.060475 0.877478793 0.001086748   FALSE
MSTRG.25090.3 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding   166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 85.140492 52.904566 105.180845 2.3994870 1.4196982 0.9912723 0.50230833 0.407600 0.575950 0.168350 0.007093040 0.001086748 FALSE TRUE
MSTRG.25090.4 ENSG00000025796 No_inf pgKDN_inf SEC63 protein_coding   166.9729 131.8958 182.7398 11.05333 2.841291 0.4703618 37.672549 35.333231 38.070374 1.0892838 1.2427855 0.1076137 0.23090833 0.271875 0.208600 -0.063275 0.433222418 0.001086748 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000025796 E001 159.7799182 1.097888e-04 1.047437e-46 1.345058e-43 6 107867756 107870764 3009 - 2.014 2.358 1.150
ENSG00000025796 E002 728.4345768 4.438924e-05 2.611983e-01 5.538911e-01 6 107870765 107871847 1083 - 2.856 2.867 0.036
ENSG00000025796 E003 63.6940111 7.918155e-04 5.167218e-01 7.724189e-01 6 107872808 107872884 77 - 1.821 1.795 -0.086
ENSG00000025796 E004 61.3438326 3.225630e-03 9.971453e-01 1.000000e+00 6 107872885 107872912 28 - 1.793 1.793 0.002
ENSG00000025796 E005 84.5535030 2.308512e-04 5.579435e-01 7.996845e-01 6 107876564 107876662 99 - 1.939 1.920 -0.065
ENSG00000025796 E006 0.4909846 1.585690e-02 8.080122e-01   6 107876663 107877400 738 - 0.156 0.191 0.353
ENSG00000025796 E007 0.4997349 2.871025e-02 2.190315e-01   6 107880960 107881148 189 - 0.085 0.262 1.938
ENSG00000025796 E008 89.9634088 1.784178e-04 9.418816e-01 9.836084e-01 6 107881149 107881250 102 - 1.958 1.956 -0.008
ENSG00000025796 E009 162.6861434 1.488512e-04 2.303046e-01 5.188490e-01 6 107882988 107883146 159 - 2.225 2.197 -0.095
ENSG00000025796 E010 8.1525041 1.702374e-03 1.138972e-10 1.131295e-08 6 107883147 107883467 321 - 0.529 1.202 2.649
ENSG00000025796 E011 99.9997297 1.224564e-03 6.272512e-02 2.516938e-01 6 107893482 107893579 98 - 1.974 2.035 0.205
ENSG00000025796 E012 82.6188999 1.875150e-04 6.056551e-02 2.470248e-01 6 107893580 107893652 73 - 1.891 1.953 0.208
ENSG00000025796 E013 38.4076858 4.645881e-04 7.599419e-01 9.059237e-01 6 107893653 107893655 3 - 1.587 1.602 0.050
ENSG00000025796 E014 0.7429934 1.386522e-02 2.664073e-01 5.598663e-01 6 107893656 107893837 182 - 0.156 0.324 1.353
ENSG00000025796 E015 58.3504223 5.578395e-03 9.449097e-01 9.847981e-01 6 107893838 107893897 60 - 1.774 1.770 -0.016
ENSG00000025796 E016 59.7920994 1.320679e-02 2.996233e-01 5.924984e-01 6 107897649 107897731 83 - 1.812 1.744 -0.229
ENSG00000025796 E017 87.6507637 2.301477e-04 3.198195e-02 1.690775e-01 6 107901370 107901517 148 - 1.977 1.907 -0.235
ENSG00000025796 E018 0.2441403 1.636206e-02 8.489290e-01   6 107901518 107901556 39 - 0.085 0.106 0.354
ENSG00000025796 E019 86.9485573 1.882504e-04 5.234505e-01 7.767096e-01 6 107902844 107902998 155 - 1.952 1.931 -0.070
ENSG00000025796 E020 69.3906529 2.147632e-04 3.877258e-01 6.734165e-01 6 107904629 107904721 93 - 1.860 1.829 -0.106
ENSG00000025796 E021 33.9765986 4.064742e-04 6.761083e-01 8.658391e-01 6 107906448 107906464 17 - 1.552 1.530 -0.074
ENSG00000025796 E022 82.0487683 1.918482e-04 3.321044e-02 1.732107e-01 6 107906465 107906580 116 - 1.949 1.878 -0.240
ENSG00000025796 E023 91.6324798 2.200233e-04 1.308254e-01 3.836418e-01 6 107906683 107906777 95 - 1.986 1.938 -0.162
ENSG00000025796 E024 75.2009736 2.278611e-04 2.149343e-01 5.005548e-01 6 107908927 107909007 81 - 1.900 1.856 -0.146
ENSG00000025796 E025 40.0608346 8.649738e-04 5.177087e-02 2.258704e-01 6 107909008 107909035 28 - 1.653 1.558 -0.323
ENSG00000025796 E026 0.4994178 3.268912e-02 2.196675e-01   6 107909036 107909159 124 - 0.085 0.262 1.938
ENSG00000025796 E027 0.2373413 1.574035e-02 3.382036e-01   6 107911168 107911345 178 - 0.156 0.000 -14.058
ENSG00000025796 E028 38.2246654 3.623471e-04 2.115975e-02 1.315387e-01 6 107911346 107911396 51 - 1.640 1.527 -0.386
ENSG00000025796 E029 40.8034922 3.825068e-04 3.225669e-02 1.699477e-01 6 107912716 107912774 59 - 1.663 1.561 -0.347
ENSG00000025796 E030 45.2580162 3.410025e-04 7.169746e-03 6.408569e-02 6 107913366 107913427 62 - 1.715 1.593 -0.415
ENSG00000025796 E031 69.9324796 3.529653e-03 5.160315e-04 8.967068e-03 6 107921797 107921909 113 - 1.913 1.759 -0.517
ENSG00000025796 E032 72.3165864 2.245865e-04 6.790526e-06 2.441602e-04 6 107924818 107924932 115 - 1.931 1.767 -0.550
ENSG00000025796 E033 37.7184052 3.717766e-04 9.940366e-03 7.994687e-02 6 107929415 107929514 100 - 1.640 1.512 -0.436
ENSG00000025796 E034 0.2542726 2.945613e-01 2.278400e-01   6 107931070 107931105 36 - 0.000 0.191 12.452
ENSG00000025796 E035 0.7273834 1.275189e-01 6.493917e-01 8.522734e-01 6 107954584 107954766 183 - 0.271 0.191 -0.647
ENSG00000025796 E036 0.2542726 2.945613e-01 2.278400e-01   6 107955575 107955624 50 - 0.000 0.191 12.452
ENSG00000025796 E037 0.6086152 1.435815e-02 8.611243e-01 9.518539e-01 6 107955965 107956026 62 - 0.217 0.191 -0.232
ENSG00000025796 E038 0.7429261 1.182919e-01 3.160460e-01 6.089464e-01 6 107956027 107956106 80 - 0.156 0.324 1.353
ENSG00000025796 E039 0.7600830 2.170100e-01 1.386040e-02 9.934985e-02 6 107957222 107957340 119 - 0.000 0.425 14.227
ENSG00000025796 E040 0.0000000       6 107957886 107958208 323 -      

Help

Please Click HERE to learn more details about the results from DEXseq.