ENSG00000027697

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367739 ENSG00000027697 No_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 1103.685 599.0605 8.500966 2.15957 -0.8815442 332.49448 366.1861 370.59500 20.16065 18.148737 0.01726599 0.57984167 0.332025 0.618525 0.286500 4.475134e-12 4.475134e-12 FALSE TRUE
ENST00000458076 ENSG00000027697 No_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 1103.685 599.0605 8.500966 2.15957 -0.8815442 69.68918 154.6105 40.36189 12.00292 4.959009 -1.93730855 0.08326667 0.140125 0.067425 -0.072700 1.118902e-03 4.475134e-12 FALSE TRUE
ENST00000696693 ENSG00000027697 No_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 1103.685 599.0605 8.500966 2.15957 -0.8815442 239.67371 520.7961 159.32846 20.01813 13.809903 -1.70865167 0.28509167 0.471550 0.266025 -0.205525 4.530266e-08 4.475134e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000027697 E001 4.469660 3.177756e-03 7.429415e-01 8.983949e-01 6 137197483 137197484 2 - 0.683 0.725 0.176
ENSG00000027697 E002 55.395768 2.759552e-04 2.362141e-01 5.254188e-01 6 137197485 137197496 12 - 1.683 1.736 0.181
ENSG00000027697 E003 2757.923665 9.769877e-05 6.620679e-16 1.222876e-13 6 137197497 137198133 637 - 3.372 3.425 0.176
ENSG00000027697 E004 3049.896087 3.678369e-05 4.230879e-03 4.416262e-02 6 137198134 137198639 506 - 3.441 3.458 0.056
ENSG00000027697 E005 1003.004251 3.522526e-05 3.859500e-03 4.143278e-02 6 137200881 137201008 128 - 2.989 2.961 -0.092
ENSG00000027697 E006 453.322420 8.206010e-05 4.143440e-01 6.946193e-01 6 137203499 137203532 34 - 2.616 2.630 0.046
ENSG00000027697 E007 759.228780 1.240614e-04 2.952379e-01 5.884712e-01 6 137203533 137203642 110 - 2.857 2.846 -0.038
ENSG00000027697 E008 483.138150 5.296109e-05 5.326586e-02 2.296986e-01 6 137203643 137203685 43 - 2.672 2.645 -0.090
ENSG00000027697 E009 4.918453 2.455921e-02 2.065228e-03 2.620231e-02 6 137203686 137203730 45 - 0.378 0.848 2.122
ENSG00000027697 E010 1017.927841 2.122319e-04 8.507393e-04 1.323443e-02 6 137204332 137204504 173 - 3.001 2.965 -0.120
ENSG00000027697 E011 521.007944 9.266024e-05 1.481447e-01 4.098504e-01 6 137206136 137206206 71 - 2.699 2.680 -0.065
ENSG00000027697 E012 448.289890 8.947942e-04 7.088335e-04 1.144960e-02 6 137206207 137206308 102 - 2.664 2.600 -0.212
ENSG00000027697 E013 3.915524 3.586939e-03 3.654850e-04 6.820784e-03 6 137206642 137206962 321 - 0.229 0.779 2.850
ENSG00000027697 E014 458.459749 1.248096e-04 1.390181e-07 7.842889e-06 6 137206963 137207077 115 - 2.683 2.604 -0.263
ENSG00000027697 E015 7.342854 2.505743e-03 3.245248e-01 6.168865e-01 6 137209850 137209972 123 - 0.816 0.925 0.418
ENSG00000027697 E016 2.011935 6.894976e-03 5.915638e-02 2.441056e-01 6 137209973 137209984 12 - 0.229 0.534 1.799
ENSG00000027697 E017 2.657123 5.483119e-03 1.528210e-03 2.077703e-02 6 137213751 137213832 82 - 0.129 0.649 3.313
ENSG00000027697 E018 23.923724 3.883777e-03 6.607008e-02 2.588327e-01 6 137215267 137215377 111 - 1.272 1.404 0.459
ENSG00000027697 E019 1.122988 2.130247e-02 4.808262e-01 7.460464e-01 6 137218028 137218060 33 - 0.229 0.344 0.799
ENSG00000027697 E020 7.445914 1.956992e-03 8.095913e-01 9.297440e-01 6 137218451 137218671 221 - 0.881 0.907 0.102
ENSG00000027697 E021 44.844344 2.018469e-03 4.205378e-01 6.998237e-01 6 137218672 137218983 312 - 1.601 1.643 0.145
ENSG00000027697 E022 15.758984 3.324919e-02 9.259611e-01 9.777382e-01 6 137218984 137219093 110 - 1.193 1.195 0.008
ENSG00000027697 E023 10.328580 1.504290e-03 4.060249e-02 1.954646e-01 6 137219094 137219242 149 - 1.141 0.960 -0.663
ENSG00000027697 E024 303.811170 7.080793e-05 1.297723e-09 1.081783e-07 6 137219243 137219449 207 - 2.524 2.415 -0.363

Help

Please Click HERE to learn more details about the results from DEXseq.