ENSG00000028137

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376259 ENSG00000028137 No_inf pgKDN_inf TNFRSF1B protein_coding protein_coding 134.1687 70.98654 156.1929 2.8362 10.47891 1.137601 51.372693 21.537303 73.502787 2.275990 12.151502 1.7704879 0.37410833 0.304550 0.477625 0.173075 0.38488758 0.02130803 FALSE TRUE
ENST00000492361 ENSG00000028137 No_inf pgKDN_inf TNFRSF1B protein_coding protein_coding_CDS_not_defined 134.1687 70.98654 156.1929 2.8362 10.47891 1.137601 50.763862 35.362113 40.255955 2.386894 9.196818 0.1869482 0.39825000 0.497625 0.258200 -0.239425 0.02130803 0.02130803 FALSE TRUE
ENST00000622420 ENSG00000028137 No_inf pgKDN_inf TNFRSF1B protein_coding miRNA 134.1687 70.98654 156.1929 2.8362 10.47891 1.137601 14.223880 2.773666 24.385148 2.773666 9.080482 3.1315363 0.08724167 0.035000 0.145675 0.110675 0.40677771 0.02130803   FALSE
MSTRG.255.1 ENSG00000028137 No_inf pgKDN_inf TNFRSF1B protein_coding   134.1687 70.98654 156.1929 2.8362 10.47891 1.137601 16.056747 6.773379 17.334543 1.828304 3.640529 1.3544059 0.11656667 0.096900 0.112975 0.016075 0.88960521 0.02130803 FALSE TRUE
MSTRG.255.6 ENSG00000028137 No_inf pgKDN_inf TNFRSF1B protein_coding   134.1687 70.98654 156.1929 2.8362 10.47891 1.137601 1.672004 4.301518 0.714493 2.486944 0.714493 -2.5731521 0.02285833 0.062975 0.005600 -0.057375 0.66883153 0.02130803 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000028137 E001 0.4893478 1.035734e-01 5.945102e-01   1 12166943 12166990 48 + 0.136 0.218 0.828
ENSG00000028137 E002 4.3678822 3.309832e-03 7.318315e-01 8.933840e-01 1 12166991 12167002 12 + 0.703 0.746 0.176
ENSG00000028137 E003 34.4160441 4.089314e-04 3.860030e-04 7.090833e-03 1 12167003 12167169 167 + 1.599 1.406 -0.664
ENSG00000028137 E004 0.9977665 2.855940e-02 2.917600e-02 1.602585e-01 1 12188013 12188115 103 + 0.136 0.471 2.413
ENSG00000028137 E005 33.5595603 4.524069e-04 2.577823e-04 5.147439e-03 1 12188796 12188895 100 + 1.591 1.389 -0.695
ENSG00000028137 E006 45.4156894 6.192908e-04 7.941882e-04 1.253548e-02 1 12190957 12191085 129 + 1.707 1.547 -0.545
ENSG00000028137 E007 33.2817155 4.458760e-04 1.281973e-02 9.440459e-02 1 12191774 12191837 64 + 1.568 1.433 -0.464
ENSG00000028137 E008 50.8624930 3.021378e-04 8.266908e-02 2.962227e-01 1 12191838 12191923 86 + 1.729 1.654 -0.255
ENSG00000028137 E009 0.2454921 1.641296e-02 6.567546e-01   1 12192348 12192430 83 + 0.073 0.123 0.828
ENSG00000028137 E010 64.8072993 2.303568e-04 3.625812e-03 3.969845e-02 1 12192431 12192524 94 + 1.844 1.731 -0.383
ENSG00000028137 E011 113.6378623 1.757606e-04 1.183275e-02 8.972133e-02 1 12192863 12193098 236 + 2.072 1.999 -0.244
ENSG00000028137 E012 60.0274651 2.786293e-04 1.254056e-02 9.303473e-02 1 12193955 12194032 78 + 1.807 1.707 -0.341
ENSG00000028137 E013 47.0055885 1.254086e-03 5.880249e-02 2.431164e-01 1 12194584 12194618 35 + 1.699 1.611 -0.302
ENSG00000028137 E014 107.3439947 1.521406e-04 1.721243e-01 4.448089e-01 1 12201967 12202171 205 + 2.036 1.996 -0.133
ENSG00000028137 E015 2.1881881 6.258611e-03 8.084662e-01 9.293027e-01 1 12206737 12206739 3 + 0.480 0.516 0.176
ENSG00000028137 E016 1387.6790016 5.057099e-05 1.515074e-18 3.615665e-16 1 12206740 12209228 2489 + 3.113 3.155 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.