ENSG00000028203

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000356859 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding protein_coding_CDS_not_defined 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.6703745 1.4555711 0.4135733 0.07720829 0.1506534 -1.7907793 0.06870000 0.164075 0.028575 -0.135500 0.071649543 0.001439965 FALSE TRUE
ENST00000436874 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding protein_coding 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.3350757 0.0000000 1.0052272 0.00000000 1.0052272 6.6656589 0.02395000 0.000000 0.071850 0.071850 0.901779462 0.001439965 FALSE TRUE
ENST00000546557 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding nonsense_mediated_decay 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.8688881 0.0000000 2.2105524 0.00000000 0.9520343 7.7947748 0.06055833 0.000000 0.150950 0.150950 0.102970936 0.001439965 FALSE FALSE
ENST00000547611 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding nonsense_mediated_decay 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 1.1215258 0.2936158 1.4379432 0.29361575 0.8937508 2.2536864 0.08301667 0.027525 0.101800 0.074275 0.836251324 0.001439965 TRUE TRUE
ENST00000547997 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding nonsense_mediated_decay 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 1.7557977 2.2274997 1.3324568 0.99237677 1.3324568 -0.7370118 0.18104167 0.273150 0.092725 -0.180425 0.391096717 0.001439965 FALSE TRUE
ENST00000549002 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding protein_coding 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.6016509 0.0000000 1.8049527 0.00000000 1.4795679 7.5037881 0.03944167 0.000000 0.118325 0.118325 0.633591662 0.001439965 FALSE FALSE
ENST00000549192 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding retained_intron 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.9879599 1.7331866 0.3841312 0.23644272 0.1608583 -2.1449792 0.09878333 0.189125 0.025525 -0.163600 0.031217124 0.001439965 FALSE TRUE
ENST00000552306 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding protein_coding_CDS_not_defined 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.4590199 1.0498726 0.0000000 0.42467075 0.0000000 -6.7277470 0.04474167 0.108850 0.000000 -0.108850 0.038903539 0.001439965 FALSE TRUE
ENST00000552660 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding nonsense_mediated_decay 11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 1.2629887 0.9333503 0.5079569 0.55499889 0.5079569 -0.8649616 0.10211667 0.099175 0.033250 -0.065925 0.776549391 0.001439965 FALSE TRUE
MSTRG.7001.13 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding   11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 0.8073696 0.0000000 2.4221088 0.00000000 1.3984601 7.9260639 0.05311667 0.000000 0.159350 0.159350 0.558203323 0.001439965 FALSE TRUE
MSTRG.7001.28 ENSG00000028203 No_inf pgKDN_inf VEZT protein_coding   11.91897 9.052088 14.69104 0.737661 0.3060454 0.6980026 1.1217376 0.0000000 2.2329014 0.00000000 0.4209407 7.8092224 0.08593333 0.000000 0.152350 0.152350 0.001439965 0.001439965 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000028203 E001 0.0000000       12 95217746 95217752 7 +      
ENSG00000028203 E002 0.0000000       12 95217753 95217760 8 +      
ENSG00000028203 E003 0.0000000       12 95217761 95217761 1 +      
ENSG00000028203 E004 0.1176306 0.0116720505 6.528810e-01   12 95217762 95217763 2 + 0.087 0.000 -10.714
ENSG00000028203 E005 0.2352613 0.2398605224 3.721370e-01   12 95217764 95217779 16 + 0.159 0.000 -13.556
ENSG00000028203 E006 0.4886223 0.0534478177 8.471863e-01   12 95217780 95217798 19 + 0.159 0.188 0.289
ENSG00000028203 E007 0.6073254 0.0158836212 8.186720e-01 0.933939748 12 95217799 95217806 8 + 0.221 0.188 -0.296
ENSG00000028203 E008 0.6073254 0.0158836212 8.186720e-01 0.933939748 12 95217807 95217807 1 + 0.221 0.188 -0.296
ENSG00000028203 E009 0.6073254 0.0158836212 8.186720e-01 0.933939748 12 95217808 95217809 2 + 0.221 0.188 -0.296
ENSG00000028203 E010 0.6073254 0.0158836212 8.186720e-01 0.933939748 12 95217810 95217810 1 + 0.221 0.188 -0.296
ENSG00000028203 E011 0.6073254 0.0158836212 8.186720e-01 0.933939748 12 95217811 95217811 1 + 0.221 0.188 -0.296
ENSG00000028203 E012 0.7259635 0.0141961777 5.600473e-01 0.800699515 12 95217812 95217817 6 + 0.275 0.188 -0.711
ENSG00000028203 E013 0.7259635 0.0141961777 5.600473e-01 0.800699515 12 95217818 95217823 6 + 0.275 0.188 -0.711
ENSG00000028203 E014 0.7259635 0.0141961777 5.600473e-01 0.800699515 12 95217824 95217825 2 + 0.275 0.188 -0.711
ENSG00000028203 E015 0.7259635 0.0141961777 5.600473e-01 0.800699515 12 95217826 95217827 2 + 0.275 0.188 -0.711
ENSG00000028203 E016 1.5686545 0.0085615596 2.949699e-01 0.588238391 12 95217828 95217841 14 + 0.476 0.319 -0.881
ENSG00000028203 E017 3.6500684 0.0109797752 5.844657e-01 0.815316256 12 95217842 95217886 45 + 0.698 0.628 -0.296
ENSG00000028203 E018 0.0000000       12 95218065 95218115 51 +      
ENSG00000028203 E019 0.0000000       12 95218116 95218128 13 +      
ENSG00000028203 E020 0.0000000       12 95218129 95218228 100 +      
ENSG00000028203 E021 0.0000000       12 95218229 95218229 1 +      
ENSG00000028203 E022 0.0000000       12 95218230 95218253 24 +      
ENSG00000028203 E023 0.0000000       12 95218254 95218254 1 +      
ENSG00000028203 E024 0.0000000       12 95218255 95218260 6 +      
ENSG00000028203 E025 0.0000000       12 95218261 95218277 17 +      
ENSG00000028203 E026 0.0000000       12 95218278 95218309 32 +      
ENSG00000028203 E027 0.0000000       12 95218310 95218345 36 +      
ENSG00000028203 E028 0.0000000       12 95218346 95218613 268 +      
ENSG00000028203 E029 0.1268540 0.0122587726 4.414977e-01   12 95224180 95224236 57 + 0.000 0.104 12.542
ENSG00000028203 E030 0.0000000       12 95231412 95231545 134 +      
ENSG00000028203 E031 0.1176306 0.0116720505 6.528810e-01   12 95242164 95242264 101 + 0.087 0.000 -13.003
ENSG00000028203 E032 0.0000000       12 95242265 95242314 50 +      
ENSG00000028203 E033 0.2373413 0.0160789775 3.166689e-01   12 95243941 95244009 69 + 0.159 0.000 -13.902
ENSG00000028203 E034 3.6387651 0.0041387929 3.520812e-01 0.642164942 12 95251940 95251944 5 + 0.717 0.599 -0.499
ENSG00000028203 E035 4.5954036 0.0033216953 9.026341e-02 0.312008383 12 95251945 95251966 22 + 0.830 0.628 -0.826
ENSG00000028203 E036 7.6446173 0.0019968013 1.660109e-01 0.436080371 12 95251967 95252071 105 + 0.994 0.859 -0.509
ENSG00000028203 E037 0.0000000       12 95252072 95252440 369 +      
ENSG00000028203 E038 4.3254660 0.0046141399 3.723542e-02 0.185781224 12 95256550 95256622 73 + 0.589 0.842 1.048
ENSG00000028203 E039 2.7100135 0.0054018902 1.929928e-01 0.472800902 12 95257150 95257153 4 + 0.476 0.655 0.820
ENSG00000028203 E040 5.2274726 0.0031917757 6.683875e-01 0.861943583 12 95257154 95257239 86 + 0.815 0.769 -0.185
ENSG00000028203 E041 0.1271363 0.0122632836 4.414565e-01   12 95258245 95258282 38 + 0.000 0.104 12.542
ENSG00000028203 E042 0.0000000       12 95258283 95258287 5 +      
ENSG00000028203 E043 0.5074127 0.0161808486 2.798246e-02 0.156264844 12 95262304 95262412 109 + 0.000 0.319 14.348
ENSG00000028203 E044 9.1821058 0.0165744346 3.043424e-02 0.164144043 12 95262906 95263081 176 + 1.097 0.875 -0.826
ENSG00000028203 E045 0.0000000       12 95263746 95263797 52 +      
ENSG00000028203 E046 19.3874006 0.0008706327 1.266129e-02 0.093621333 12 95266357 95266632 276 + 1.377 1.215 -0.564
ENSG00000028203 E047 0.0000000       12 95266633 95266633 1 +      
ENSG00000028203 E048 0.2542726 0.2398167708 2.287460e-01   12 95269824 95270038 215 + 0.000 0.188 13.146
ENSG00000028203 E049 2.0377028 0.0075487587 6.752708e-02 0.262171334 12 95270039 95270050 12 + 0.589 0.319 -1.411
ENSG00000028203 E050 9.8427663 0.0051805541 4.411649e-01 0.716685260 12 95270051 95270188 138 + 1.065 0.997 -0.251
ENSG00000028203 E051 2.9213386 0.0261210844 7.553131e-01 0.903589405 12 95274742 95274745 4 + 0.613 0.569 -0.196
ENSG00000028203 E052 8.1863734 0.0030766450 6.650967e-01 0.860718976 12 95274746 95274889 144 + 0.942 0.985 0.160
ENSG00000028203 E053 0.0000000       12 95274890 95274891 2 +      
ENSG00000028203 E054 4.7779791 0.0338686971 4.778062e-01 0.743953044 12 95282313 95282359 47 + 0.717 0.807 0.363
ENSG00000028203 E055 15.6616189 0.0011660086 4.438392e-01 0.718495084 12 95282360 95282644 285 + 1.193 1.250 0.199
ENSG00000028203 E056 12.9554370 0.0016304551 2.596169e-02 0.148996935 12 95287664 95287857 194 + 1.217 1.042 -0.631
ENSG00000028203 E057 0.1170040 0.0116268137 6.528875e-01   12 95287858 95287864 7 + 0.087 0.000 -13.003
ENSG00000028203 E058 0.0000000       12 95293684 95294271 588 +      
ENSG00000028203 E059 9.8006293 0.0015870701 3.794554e-01 0.666216021 12 95294272 95294372 101 + 0.994 1.073 0.289
ENSG00000028203 E060 4.0903276 0.0034258389 1.324019e-02 0.096432124 12 95296051 95296068 18 + 0.536 0.842 1.289
ENSG00000028203 E061 15.1509671 0.0010866942 7.072194e-01 0.881169256 12 95296069 95296258 190 + 1.194 1.223 0.103
ENSG00000028203 E062 2.1418728 0.0064277079 2.109026e-04 0.004369889 12 95296259 95296956 698 + 0.159 0.704 3.196
ENSG00000028203 E063 3.1631063 0.0052677247 7.750505e-01 0.913555859 12 95298862 95298943 82 + 0.636 0.599 -0.158
ENSG00000028203 E064 8.0860909 0.0017732875 8.643482e-06 0.000301343 12 95299094 95300164 1071 + 0.698 1.137 1.674
ENSG00000028203 E065 87.1115700 0.0004043147 3.501180e-01 0.640327778 12 95300165 95302799 2635 + 1.931 1.958 0.091

Help

Please Click HERE to learn more details about the results from DEXseq.