ENSG00000033170

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360689 ENSG00000033170 No_inf pgKDN_inf FUT8 protein_coding protein_coding 34.60911 16.22041 43.28829 1.025727 1.776843 1.415611 2.3454436 1.575216 2.901364 0.3943141 0.6078792 0.8770158 0.07461667 0.099325 0.067875 -0.031450 0.84201875 0.03929616 FALSE TRUE
ENST00000549235 ENSG00000033170 No_inf pgKDN_inf FUT8 protein_coding protein_coding_CDS_not_defined 34.60911 16.22041 43.28829 1.025727 1.776843 1.415611 0.4447018 1.334105 0.000000 0.9549912 0.0000000 -7.0705024 0.02433333 0.073000 0.000000 -0.073000 0.28810751 0.03929616   FALSE
ENST00000557164 ENSG00000033170 No_inf pgKDN_inf FUT8 protein_coding protein_coding 34.60911 16.22041 43.28829 1.025727 1.776843 1.415611 4.3159140 5.656636 4.078720 0.9391883 2.0367167 -0.4708432 0.17168333 0.351400 0.090925 -0.260475 0.19830298 0.03929616 FALSE TRUE
ENST00000673929 ENSG00000033170 No_inf pgKDN_inf FUT8 protein_coding protein_coding 34.60911 16.22041 43.28829 1.025727 1.776843 1.415611 19.6390718 5.357577 28.598981 1.3282163 2.2788018 2.4141253 0.51674167 0.321525 0.666900 0.345375 0.03929616 0.03929616 FALSE TRUE
ENST00000674118 ENSG00000033170 No_inf pgKDN_inf FUT8 protein_coding protein_coding 34.60911 16.22041 43.28829 1.025727 1.776843 1.415611 2.2063907 1.862584 0.000000 1.8625837 0.0000000 -7.5488864 0.08097500 0.127900 0.000000 -0.127900 0.79760921 0.03929616 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000033170 E001 3.0592334 0.0049392461 4.108231e-02 0.1966743586 14 65410592 65411121 530 + 0.478 0.753 1.214
ENSG00000033170 E002 0.2448930 0.0162517618 4.703416e-01   14 65411122 65411862 741 + 0.062 0.142 1.329
ENSG00000033170 E003 0.0000000       14 65411863 65411864 2 +      
ENSG00000033170 E004 0.0000000       14 65411865 65411873 9 +      
ENSG00000033170 E005 0.0000000       14 65411874 65411890 17 +      
ENSG00000033170 E006 0.0000000       14 65411891 65411935 45 +      
ENSG00000033170 E007 0.0000000       14 65411936 65411993 58 +      
ENSG00000033170 E008 6.7159392 0.0454407712 4.630371e-01 0.7331114127 14 65412730 65412980 251 + 0.883 0.781 -0.396
ENSG00000033170 E009 3.8075438 0.0109152053 3.557851e-02 0.1806695970 14 65412981 65413005 25 + 0.726 0.407 -1.478
ENSG00000033170 E010 2.4930983 0.0221374212 4.049950e-02 0.1951836367 14 65413006 65413007 2 + 0.595 0.249 -1.919
ENSG00000033170 E011 2.4947325 0.0065124511 3.502998e-02 0.1791419573 14 65413008 65413018 11 + 0.595 0.249 -1.919
ENSG00000033170 E012 1.4238616 0.0092410574 8.850522e-02 0.3086207159 14 65413019 65413021 3 + 0.431 0.142 -2.130
ENSG00000033170 E013 4.7831133 0.0028579507 1.102541e-01 0.3483973469 14 65413022 65413068 47 + 0.785 0.570 -0.908
ENSG00000033170 E014 15.3818448 0.0009082587 3.456023e-05 0.0009743707 14 65413069 65413214 146 + 1.262 0.881 -1.391
ENSG00000033170 E015 1.0681330 0.0118532345 2.175383e-01 0.5039830111 14 65430216 65430309 94 + 0.349 0.142 -1.671
ENSG00000033170 E016 15.6160549 0.0009126449 6.247432e-05 0.0015969146 14 65455621 65455718 98 + 1.266 0.902 -1.321
ENSG00000033170 E017 0.3635311 0.0167751363 8.286774e-01   14 65457894 65458188 295 + 0.117 0.142 0.329
ENSG00000033170 E018 0.0000000       14 65479707 65479784 78 +      
ENSG00000033170 E019 0.0000000       14 65488318 65488583 266 +      
ENSG00000033170 E020 0.1187032 0.0118075018 1.000000e+00   14 65516243 65516388 146 + 0.062 0.001 -6.883
ENSG00000033170 E021 61.0001016 0.0002486330 8.160720e-03 0.0700302754 14 65561337 65561766 430 + 1.786 1.674 -0.380
ENSG00000033170 E022 26.1424817 0.0005470921 7.965117e-01 0.9229378274 14 65615978 65616093 116 + 1.402 1.385 -0.058
ENSG00000033170 E023 32.6145394 0.0004413874 2.638909e-01 0.5570307411 14 65616211 65616373 163 + 1.471 1.531 0.207
ENSG00000033170 E024 0.9616056 0.0118019197 8.285408e-01 0.9379451681 14 65617090 65617191 102 + 0.285 0.249 -0.256
ENSG00000033170 E025 28.8183766 0.0004614902 8.788439e-01 0.9590123907 14 65629492 65629606 115 + 1.435 1.444 0.028
ENSG00000033170 E026 0.0000000       14 65636516 65636516 1 +      
ENSG00000033170 E027 0.0000000       14 65636517 65636622 106 +      
ENSG00000033170 E028 0.0000000       14 65645960 65646117 158 +      
ENSG00000033170 E029 0.0000000       14 65646520 65646598 79 +      
ENSG00000033170 E030 54.6208149 0.0002922842 6.512469e-01 0.8530853257 14 65669243 65669480 238 + 1.703 1.721 0.063
ENSG00000033170 E031 50.0331595 0.0016555577 9.145255e-01 0.9730938902 14 65721775 65722021 247 + 1.672 1.666 -0.020
ENSG00000033170 E032 36.6708956 0.0022394307 6.653702e-01 0.8608044898 14 65724147 65724323 177 + 1.532 1.555 0.080
ENSG00000033170 E033 21.5915310 0.0008906267 8.545460e-01 0.9487278400 14 65733231 65733277 47 + 1.314 1.326 0.041
ENSG00000033170 E034 36.3797877 0.0003720071 7.092659e-01 0.8823533656 14 65733278 65733381 104 + 1.542 1.521 -0.070
ENSG00000033170 E035 236.7914204 0.0001184982 1.141653e-05 0.0003833994 14 65742093 65744121 2029 + 2.315 2.389 0.246

Help

Please Click HERE to learn more details about the results from DEXseq.