ENSG00000033800

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000563996 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding nonsense_mediated_decay 20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 2.4428646 3.4000004 3.089896 1.1772931 0.5605744 -0.137552 0.12449167 0.174775 0.158300 -0.016475 1.00000000 0.03795423   FALSE
ENST00000564915 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding nonsense_mediated_decay 20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 2.5692576 1.6488557 0.000000 0.8514452 0.0000000 -7.374045 0.10974167 0.078400 0.000000 -0.078400 0.06013728 0.03795423 TRUE TRUE
MSTRG.9814.14 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding   20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 1.5088393 0.8475424 1.858266 0.8475424 0.6526055 1.123420 0.06934167 0.033950 0.092450 0.058500 0.49206860 0.03795423 FALSE FALSE
MSTRG.9814.2 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding   20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 2.3697835 4.9754141 1.065866 0.4241754 0.5085197 -2.212214 0.13260833 0.287775 0.058350 -0.229425 0.03795423 0.03795423 TRUE TRUE
MSTRG.9814.4 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding   20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 0.6375371 0.0000000 1.696367 0.0000000 0.9187315 7.414784 0.03265000 0.000000 0.088125 0.088125 0.09872796 0.03795423 TRUE TRUE
MSTRG.9814.6 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding   20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 7.2284033 5.3001512 8.211980 0.5199665 0.8394895 0.630733 0.36578333 0.297225 0.423850 0.126625 0.57463903 0.03795423 TRUE TRUE
MSTRG.9814.7 ENSG00000033800 No_inf pgKDN_inf PIAS1 protein_coding   20.01893 18.31579 19.34703 2.338726 0.7849662 0.07898249 1.4161786 0.8111405 1.806309 0.3300726 0.6631732 1.145309 0.07311667 0.047400 0.096650 0.049250 0.83649832 0.03795423 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000033800 E001 0.1271363 0.0122822504 5.654027e-01   15 68054309 68054314 6 + 0.000 0.093 10.593
ENSG00000033800 E002 0.1271363 0.0122822504 5.654027e-01   15 68054315 68054317 3 + 0.000 0.093 12.569
ENSG00000033800 E003 0.1271363 0.0122822504 5.654027e-01   15 68054318 68054321 4 + 0.000 0.093 12.569
ENSG00000033800 E004 3.0252370 0.0095067224 5.735473e-02 2.394435e-01 15 68054322 68054350 29 + 0.720 0.465 -1.151
ENSG00000033800 E005 0.3712740 0.0167761559 6.149611e-01   15 68054576 68055231 656 + 0.097 0.170 0.936
ENSG00000033800 E006 0.2438580 0.0160694886 9.695935e-01   15 68055799 68055913 115 + 0.097 0.093 -0.064
ENSG00000033800 E007 0.0000000       15 68057480 68057580 101 +      
ENSG00000033800 E008 0.1265070 0.0122620044 5.652413e-01   15 68061398 68061449 52 + 0.000 0.093 12.569
ENSG00000033800 E009 35.4701393 0.0005732132 2.467351e-01 5.373257e-01 15 68086306 68086750 445 + 1.589 1.535 -0.183
ENSG00000033800 E010 0.1265070 0.0122620044 5.652413e-01   15 68087842 68087890 49 + 0.000 0.093 12.569
ENSG00000033800 E011 10.4027224 0.0013772830 7.362720e-01 8.953403e-01 15 68141946 68142030 85 + 1.070 1.044 -0.098
ENSG00000033800 E012 6.9540241 0.0023550947 3.990263e-01 6.827972e-01 15 68142290 68142337 48 + 0.942 0.859 -0.317
ENSG00000033800 E013 0.1186381 0.0117439263 5.120448e-01   15 68142338 68142339 2 + 0.097 0.000 -13.106
ENSG00000033800 E014 10.5020481 0.0013437389 3.805844e-01 6.670661e-01 15 68145816 68145906 91 + 1.097 1.024 -0.265
ENSG00000033800 E015 10.6020545 0.0060170332 1.178267e-01 3.625675e-01 15 68146566 68146661 96 + 1.131 0.994 -0.498
ENSG00000033800 E016 6.5642456 0.0070082419 7.777431e-02 2.853718e-01 15 68146662 68146700 39 + 0.967 0.780 -0.716
ENSG00000033800 E017 10.3536007 0.0014703879 1.015724e-01 3.328193e-01 15 68153590 68153695 106 + 1.123 0.983 -0.508
ENSG00000033800 E018 0.4899121 0.0161271342 9.604336e-01   15 68153696 68153961 266 + 0.176 0.170 -0.064
ENSG00000033800 E019 10.9725314 0.0029346945 1.397782e-01 3.976541e-01 15 68164731 68164804 74 + 1.139 1.014 -0.451
ENSG00000033800 E020 19.3508391 0.0006808144 1.291957e-02 9.492633e-02 15 68173732 68173892 161 + 1.385 1.225 -0.558
ENSG00000033800 E021 19.7208135 0.0007232177 8.107762e-01 9.303519e-01 15 68175637 68175767 131 + 1.323 1.309 -0.046
ENSG00000033800 E022 15.9020673 0.0008496440 5.233725e-01 7.766767e-01 15 68176474 68176537 64 + 1.250 1.206 -0.152
ENSG00000033800 E023 22.9232168 0.0006086655 4.821505e-02 2.161442e-01 15 68176538 68176654 117 + 1.436 1.320 -0.403
ENSG00000033800 E024 0.0000000       15 68181211 68181211 1 +      
ENSG00000033800 E025 31.1447681 0.0042396858 2.187260e-01 5.054020e-01 15 68181212 68181354 143 + 1.541 1.473 -0.234
ENSG00000033800 E026 0.6347396 0.0151203772 2.345522e-02 1.399683e-01 15 68181426 68181873 448 + 0.000 0.342 14.785
ENSG00000033800 E027 11.5680600 0.0213344082 2.059419e-01 4.894364e-01 15 68183630 68183667 38 + 1.162 1.034 -0.461
ENSG00000033800 E028 59.7176335 0.0073918093 8.288524e-01 9.381300e-01 15 68187542 68188231 690 + 1.777 1.788 0.037
ENSG00000033800 E029 36.2424045 0.0007993035 2.946753e-01 5.879575e-01 15 68188232 68189202 971 + 1.541 1.594 0.181
ENSG00000033800 E030 5.0612556 0.0030981394 2.144712e-01 4.998613e-01 15 68189203 68189270 68 + 0.699 0.844 0.580
ENSG00000033800 E031 45.6238754 0.0003326758 5.195503e-02 2.263099e-01 15 68189271 68190492 1222 + 1.621 1.706 0.288
ENSG00000033800 E032 9.2170321 0.0113731814 5.961194e-01 8.224892e-01 15 68190493 68190607 115 + 0.978 1.034 0.207
ENSG00000033800 E033 4.5501896 0.0423127550 5.826105e-01 8.140436e-01 15 68190608 68191681 1074 + 0.699 0.780 0.329
ENSG00000033800 E034 0.0000000       15 68191682 68191694 13 +      
ENSG00000033800 E035 0.0000000       15 68191695 68191806 112 +      
ENSG00000033800 E036 0.0000000       15 68191807 68192153 347 +      
ENSG00000033800 E037 0.0000000       15 68192154 68192302 149 +      
ENSG00000033800 E038 0.0000000       15 68192303 68193515 1213 +      
ENSG00000033800 E039 0.0000000       15 68193516 68193645 130 +      
ENSG00000033800 E040 0.0000000       15 68193646 68193852 207 +      
ENSG00000033800 E041 0.2441403 0.0161611247 9.693255e-01   15 68195798 68195826 29 + 0.097 0.093 -0.064
ENSG00000033800 E042 35.7341734 0.0008230779 3.257709e-14 5.152530e-12 15 68197633 68199487 1855 + 1.312 1.708 1.358

Help

Please Click HERE to learn more details about the results from DEXseq.